1,083 research outputs found

    Super-Virasoro Anomaly, Super-Weyl Anomaly and the Super-Liouville Action for 2D Supergravity

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    The relation between super-Virasoro anomaly and super-Weyl anomaly in N=1N=1 NSR superstring coupled with 2D supergravity is investigated from canonical theoretical view point. The WZW action canceling the super-Virasoro anomaly is explicitly constructed. It is super-Weyl invariant but nonlocal functional of 2D supergravity. The nonlocality can be remedied by the super-Liouvlle action, which in turn recovers the super-Weyl anomaly. The final gravitational effective action turns out to be local but noncovariant super-Liouville action, describing the dynamical behavior of the super-Liouville fields. The BRST invariance of this approach is examined in the superconformal gauge and in the light-cone gauge.Comment: 45 page

    Axial Anomaly in Lattice Abelian Gauge Theory in Arbitrary Dimensions

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    Axial anomaly of lattice abelian gauge theory in hyper-cubic regular lattice in arbitrary even dimensions is investigated by applying the method of exterior differential calculus. The topological invariance, gauge invariance and locality of the axial anomaly determine the explicit form of the topological part. The anomaly is obtained up to a multiplicative constant for finite lattice spacing and can be interpreted as the Chern character of the abelian lattice gauge theory.Comment: LaTeX, 10 page

    Precocious activation of APC/C-Cdh1 at pre-anaphase causes genome instability

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    Faithful chromosome segregation and thereby accurate gene transmission are crucial for all organisms. Until proper attachment of the mitotic spindle to the kinetochore is established, the ubiquitin ligase (E3) Cdc20-activated APC/C (anaphase promoting complex/cyclosome) is repressed by the spindle assembly checkpoint (SAC) and sister chromatin cohesion is protected. Mutants defective in SAC fail to arrest at metaphase even in the presence of damaged microtubules. Interestingly, a similar phenomenon occurs in yeast cells defective in Bub2, a negative factor of the mitotic exit network (MEN), which is required for telophase onset, although its precise molecular mechanism is unknown. Here, we show that chromosome missegregation occurs frequently in bub2∆ cells in the presence of damaged microtubules. The loss of Bub2 caused precocious activation of APC/C-Cdh1/Hct1 at pre-anaphase, leading to securin degradation and then separase-mediated cohesin cleavage. Overexpression of CDH1 and CDC14, encoding Cdc14 phosphatase, at pre-anaphase similarly caused chromosome missegregation. Thus, sequential activation of APC/C-Cdc20 and then APC/C-Cdh1 is critical for precise chromosome segregation and precocious activation of APC/C-Cdh1 at pre-anaphase causes genomic instability. Since degradation of human securin is also mediated by APC/C-Cdc20 and APC/C-Cdh1, this study predicts that precocious activation APC/C-Cdh1 in human cells similarly causes genomic instability, and thereby cell death or tumorigenesis

    Revisit of magnetic orders in 1/1 approximant crystals of Tsai-type quasicrystal from theoretical points of view

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    The various magnetic orders observed in approximant crystals of Tsai-type quasicrystal are important for deepening our understanding of mysterious magnetism in quasicrystals. Using an icosahedral cluster model with inter-cluster interactions, we give an intuitive explanation of the mechanism of magnetic orders previously reported by classical Monte-Carlo simulations for an approximant-crystal model describing a Gd-based Tsai-type 1/1 approximant crystal.Comment: 2 pages, 2 figure
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