Miniaturization of ultra low profile inverted L antenna on rectangular conductor

The ultra low profile inverted L antenna, whose horizontal element is bent as a meander line shape, is proposed and numerically analyzed for the reception antenna for the keyless entry system of automobiles at 315 MHz band. In the case of the conducting plane of 70 mm by 350 mm and the antenna height of 31.7 mm, the directivity of 2.48 dBi is obtained. In the numerical analysis, the electromagnetic simulator WIPL-D based on the Method of Moment is used.2011 IEEE International Symposium on Antennas and Propagation and USNC/URSI National Radio Science Meeting, APSURSI 2011; Spokane, WA; 3 July 2011 through 8 July 201

Multidrug Sensitive Yeast Strains, Useful Tools for Chemical Genetics

The budding yeast Saccharomyces cerevisiae is a useful eukaryote model organism for application to chemical biology studies, for example, drug screening, drug evaluation, and target identification. To use yeast for chemical biology research, however, it has been necessary to construct yeast strains suitable for various compounds because of their high drug resistance. Hence, the deletion of all multidrug resistance genes except for those that are important for viability and for genetic experiments/manipulation could increase the drug sensitivity without influencing the transformation, mating, or sporulation efficiency. There are two major factors conferring multidrug resistance in S. cerevisiae: one is the drug efflux system and the other is the permeability barrier. We therefore constructed a strain which shows high sensitivity to multiple drugs by disrupting the drug efflux system using ATP-binding cassette transporters and suppressing the membrane barrier system by introducing an ERG6-inducible system. In this review, we discuss the construction of our multidrug-sensitive yeast strains and their application in chemical biology

Characteristics of Clinical and Imaging Findings of Epidermoid Cysts under the Skin of the Mental Region

Epidermoid cyst often arises in the fl oor of oral cavity; however, it is relatively rare to arise subcutaneously in the mental region. We reported characteristics of clinical and imaging fi ndings of epidermoid cysts under the skin of the mental region. The patient was a 53-year-old male. He complained of a subcutaneous mass without pain in the left mental region. A palpable soft and movable thumb-sized mass without pain was observed at the fi rst examination. Ultrasound examination revealed a well-demarcated mass with heterogenous hyper-echoic internal echo and posterior echo enhancement. On power Doppler sonography, a small amount of blood supply was found around the periphery of the mass. Plain CT scan revealeda globular soft-tissue mass with peripheral high and central low CT values area. The mass was removed under local anesthesia using intraoral approach. A histopathologic diagnosis was epidermoid cyst. Recurrence is not observed 2 years after surgery. There were only 3 reports of epidermoid cysts in the mental region, including our case in Japan, clinically characteristics of age ranging 20 to 66 years of age and the mean age of 46 years, with 2 males and 1 female. The size wasfrom 20 mm to 12 mm in diameter and from the tip of a thumb up to the tip of a small fi nger. Ultrasound images of the inside of epidermoid cysts that we experienced this time showed enhancement of relatively uniform hyperechoic image and posterior echo, which was characteristically slightly diff erent from fi ndings of epidermoid cysts generally reported

Neutral atom emission coming from the direction of the high-latitude magnetopause under northward IMF

The Low Energy Neutral Atom (LENA) imager on the Imager for Magnetopause-to-Aurora Global Exploration (IMAGE) spacecraft in the magnetosphere can detect neutral particles coming from the direction of the magnetopause. During a period of dynamic pressure of ～6 nPa and IMF B_Z of ～15nT on March 27, 2001, significant neutral atom emissions occurred in the direction of the very high-latitude magnetopause. Simultaneous observations from IMAGE/LENA and SuperDARN radar show that the LENA emission appears concurrently with the enhancement of the sunward flow of the reverse convection in the ionosphere. In a recent paper (S. Taguchi et al., Geophys. Res. Lett., 33, L03101, doi: 10.1029/2005GL025020, 2006) this type of emission has been interpreted as being produced by the fast ion flow caused by cusp reconnection through charge exchange with the Earth\u27s hydrogen exosphere. In other words, remote sensing using LENA imager can be applied in order to determine the stability of the reconnection site. From results of analyses of LENA emission data we show that the reconnection "spot" mapped on a sphere having a radius of 8 R_E shifts tailward by approximately 1 R_E over 10min while fluctuating

Simultaneous observations of the cusp with IMAGE Low Energy Neutral Atom Imager and SuperDARN radar

The Low Energy Neutral Atom (LENA) imager on the IMAGE spacecraft observed significant emission in the high-latitude magnetosheath direction during an extreme solar wind condition on April 11, 2001. The emission was modulated in such a manner that the sources shifted equatorward in the high-latitude sheath while sometimes undergoing brief poleward returns. This modulation and the IMF BZ tend to have correlative variations. During this interval of interest, SuperDARN was receiving strong backscattered signals from large potions of the dayside ionosphere. This observation indicates that the equatorward motion of the cusp latitude consists of rapid and slow phases. This kind of equatorward shift appears to correlate with the motion of the emission observed by LENA in the direction of the high-latitude sheath, which gives evidence for a means for monitoring the high-altitude cusp using IMAGE/LENA. It thus appears that the two remote sensing observations, i.e., IMAGE/LENA and SuperDARN radar would provide promising opportunities to understand the detailed dynamics of the polar cusp extending from the low-altitudes to the high-altitudes

Five amino acid residues in cysteine-rich domain of human T1R3 were involved in the response for sweet-tasting protein, thaumatin.

Thaumatin, a sweet-tasting plant protein, elicits a sweet taste sensation at 50 nM in humans but not rodents. Although it was shown that the cysteine-rich domain (CRD) of human T1R3 (hT1R3) is important for the response to thaumatin, the amino acid residues within CRD critical for response are still unknown. A comparison of the amino acid sequence (69 amino acid residues) of CRD between hT1R3 and mouse T1R3 (mT1R3) revealed sixteen amino acids that differ. In the present study, we converted each of these sixteen amino acids in hT1R3 to their mouse counterpart and examined the response to thaumatin and sucralose using a cell-based assay. No significant decrease in the response to sucralose was seen among any of the sixteen mutants. However, five mutants (Q504K, A537T, R556P, S559P, and R560K) exhibited a significantly diminished response to thaumatin. The five critical residues involved in the response to thaumatin were dispersed in the CRD of hT1R3 and widely distributed when compared to brazzein. The unique intense sweet-taste of thaumatin might be attributed to the different receptor activation mechanism compared to the small molecule sweetener sucralose