32,352 research outputs found
Coherent states for compact Lie groups and their large-N limits
The first two parts of this article surveys results related to the
heat-kernel coherent states for a compact Lie group K. I begin by reviewing the
definition of the coherent states, their resolution of the identity, and the
associated Segal-Bargmann transform. I then describe related results including
connections to geometric quantization and (1+1)-dimensional Yang--Mills theory,
the associated coherent states on spheres, and applications to quantum gravity.
The third part of this article summarizes recent work of mine with Driver and
Kemp on the large-N limit of the Segal--Bargmann transform for the unitary
group U(N). A key result is the identification of the leading-order large-N
behavior of the Laplacian on "trace polynomials."Comment: Submitted to the proceeding of the CIRM conference, "Coherent states
and their applications: A contemporary panorama.
Incorporating remote visits into an outpatient clinic
Copyright @ 2009 Operational Research Society Ltd. This is a post-peer-review, pre-copyedit version of an article published in Journal of Simulation. The definitive publisher-authenticated version Eatock and Eldabi (2009), "Incorporating remote visits into an outpatient clinic", Journal of Simulation, 3, 179–188 is available online at the link below.Most telemedicine studies are concerned with either the technological or diagnostic comparisons, rather than assessing the impact on clinic management. This has attributed to the retrospective nature of the studies, with lack of data being the main cause for not using simulation for prospective analysis. This article demonstrates the use of simulation to assess the impact of prospective systems by utilising data generated from clinical trials. The example used here is the introduction of remote consultations into an outpatient's clinic. The article addresses the issues of using secondary data, in terms of the differences between the trial, the model and future reality. The result of running the simulation model show that exchanging the mode of service delivery does not improve patient wait times as expected, and that a protocol change in association with the introduction of remote visits is necessary to provide a substantial reduction in patient wait times
The Turkey Ig-like receptor family: identification, expression and function.
The chicken leukocyte receptor complex located on microchromosome 31 encodes the chicken Ig-like receptors (CHIR), a vastly expanded gene family which can be further divided into three subgroups: activating CHIR-A, bifunctional CHIR-AB and inhibitory CHIR-B. Here, we investigated the presence of CHIR homologues in other bird species. The available genome databases of turkey, duck and zebra finch were screened with different strategies including BLAST searches employing various CHIR sequences, and keyword searches. We could not identify CHIR homologues in the distantly related zebra finch and duck, however, several partial and complete sequences of CHIR homologues were identified on chromosome 3 of the turkey genome. They were designated as turkey Ig-like receptors (TILR). Using cDNA derived from turkey blood and spleen RNA, six full length TILR could be amplified and further divided according to the typical sequence features into one activating TILR-A, one inhibitory TILR-B and four bifunctional TILR-AB. Since the TILR-AB sequences all displayed the critical residues shown to be involved in binding to IgY, we next confirmed the IgY binding using a soluble TILR-AB1-huIg fusion protein. This fusion protein reacted with IgY derived from various gallinaceous birds, but not with IgY from other bird species. Finally, we tested various mab directed against CHIR for their crossreactivity with either turkey or duck leukocytes. Whereas no staining was detectable with duck cells, the CHIR-AB1 specific mab 8D12 and the CHIR-A2 specific mab 13E2 both reacted with a leukocyte subpopulation that was further identified as thrombocytes by double immunofluorescence employing B-cell, T-cell and thrombocyte specific reagents. In summary, although the turkey harbors similar LRC genes as the chicken, their distribution seems to be distinct with predominance on thrombocytes rather than lymphocytes
Recommended from our members
Monoaromatic compounds in ambient air of various cities: A focus on correlations between the xylenes and ethylbenzene
Speciation of o-xylene, m-xylene, p-xylene and ethylbenzene was performed by gas chromatography from ambient air and liquid fuel samples collected at various locations in 19 cities in Europe, Asia and South America. The xylene's mixing ratios were compared to each other from the various locations, which included urban air, traffic air and liquid fuel. For all samples, the xylenes exhibited robust correlations, and the slopes remained constant. The m-xylene/p-xylene ratio was found to be 2.33±0.30, and the m-xylene/o-xylene ratio was found to be 1.84±0.25. These ratios remain persistent even in biomass combustion experiments (in South America and South Africa). Comparing the xylenes to toluene and benzene indicate that combustion, but not fuel evaporation, is the major common source of the xylenes in areas dominated by automotive emissions. Although a wide range of combustion types and combustion efficiencies were encountered throughout all the locations investigated, xylenes and ethylbenzene ratios remained persistent. We discuss the implications of the constancies in the xylenes and ethylbenzene ratios on atmospheric chemistry
The calculation of sparticle and Higgs decays in the minimal and next-to-minimal supersymmetric standard models: SOFTSUSY4.0
We describe a major extension of the SOFTSUSY spectrum calculator to include
the calculation of the decays, branching ratios and lifetimes of sparticles
into lighter sparticles, covering the next-to-minimal supersymmetric standard
model (NMSSM) as well as the minimal supersymmetric standard model (MSSM). This
document acts as a manual for the new version of SOFTSUSY, which includes the
calculation of sparticle decays. We present a comprehensive collection of
explicit expressions used by the program for the various partial widths of the
different decay modes in the appendix
The impact of the ATLAS zero-lepton, jets and missing momentum search on a CMSSM fit
Recent ATLAS data significantly extend the exclusion limits for
supersymmetric particles. We examine the impact of such data on global fits of
the constrained minimal supersymmetric standard model (CMSSM) to indirect and
cosmological data. We calculate the likelihood map of the ATLAS search, taking
into account systematic errors on the signal and on the background. We validate
our calculation against the ATLAS determinaton of 95% confidence level
exclusion contours. A previous CMSSM global fit is then re-weighted by the
likelihood map, which takes a bite at the high probability density region of
the global fit, pushing scalar and gaugino masses up.Comment: 16 pages, 7 figures. v2 has bigger figures and fixed typos. v3 has
clarified explanation of our handling of signal systematic
The impact of a diagnostic decision support system on the consultation: perceptions of GPs and patients
Background Clinical decision support systems (DSS) aimed at supporting diagnosis are not widely used. This is mainly due to usability issues and lack of integration into clinical work and the electronic health record (EHR). In this study we examined the usability and acceptability of a diagnostic DSS prototype integrated with the EHR and in comparison with the EHR alone. Methods Thirty-four General Practitioners (GPs) consulted with 6 standardised patients (SPs) using only their EHR system (baseline session); on another day, they consulted with 6 different but matched for difficulty SPs, using the EHR with the integrated DSS prototype (DSS session). GPs were interviewed twice (at the end of each session), and completed the Post-Study System Usability Questionnaire at the end of the DSS session. The SPs completed the Consultation Satisfaction Questionnaire after each consultation. Results The majority of GPs (74%) found the DSS useful: it helped them consider more diagnoses and ask more targeted questions. They considered three user interface features to be the most useful: (1) integration with the EHR; (2) suggested diagnoses to consider at the start of the consultation and; (3) the checklist of symptoms and signs in relation to each suggested diagnosis. There were also criticisms: half of the GPs felt that the DSS changed their consultation style, by requiring them to code symptoms and signs while interacting with the patient. SPs sometimes commented that GPs were looking at their computer more than at them; this comment was made more often in the DSS session (15%) than in the baseline session (3%). Nevertheless, SP ratings on the satisfaction questionnaire did not differ between the two sessions. Conclusions To use the DSS effectively, GPs would need to adapt their consultation style, so that they code more information during rather than at the end of the consultation. This presents a potential barrier to adoption. Training GPs to use the system in a patient-centred way, as well as improvement of the DSS interface itself, could facilitate coding. To enhance patient acceptability, patients should be informed about the potential of the DSS to improve diagnostic accuracy
R-parity violating resonant stop production at the Large Hadron Collider
We have investigated the resonant production of a stop at the Large Hadron
Collider, driven by baryon number violating interactions in supersymmetry. We
work in the framework of minimal supergravity models with the lightest
neutralino being the lightest supersymmetric particle which decays within the
detector. We look at various dilepton and trilepton final states, with or
without b-tags. A detailed background simulation is performed, and all possible
decay modes of the lighter stop are taken into account. We find that higher
stop masses are sometimes easier to probe, through the decay of the stop into
the third or fourth neutralino and their subsequent cascades. We also comment
on the detectability of such signals during the 7 TeV run, where, as expected,
only relatively light stops can be probed. Our conclusion is that the resonant
process may be probed, at both 10 and 14 TeV, with the R-parity violating
coupling {\lambda}"_{312} as low as 0.05, for a stop mass of about 1 TeV. The
possibility of distinguishing between resonant stop production and
pair-production is also discussed.Comment: 20 pages, 4 figures, 6 tables; Version accepted by JHE
Large hadron collider constraints on some simple Z models for b → sμ+μ− anomalies
We examine current Large Hadron Collider constraints on some simple Z models that significantly improve
on Standard Model fits to b → sμ+μ− transition data. The
models that we consider are the ‘third family baryon number minus second family lepton number’ (B3 − L2) model
and the ‘third family hypercharge’ model and variants. The
constraints are applied on parameter regions of each model
that fit the b → sμ+μ− transition data and come from highmass Drell–Yan di-muons and measurements of Standard
Model processes. This latter set of observables place particularly strong bounds upon the parameter space of the B3 − L2
model when the mass of the Z boson is less than 300 GeV
Nonlocal Charges for Bonus Yangian Symmetries of Super-Yang-Mills
The existence of a "bonus" U(1) level-one Yangian symmetry of N=4
super-Yang-Mills has recently been proposed. We provide evidence for this
proposal by constructing the BRST-invariant nonlocal charge in the pure spinor
sigma model corresponding to this bonus level-one symmetry. We also construct
analogous charges for bonus U(1) symmetries at all odd levels of the Yangian.Comment: LaTeX 16p
- …