Ethnic and religious aspects of gender behavior and reproductive directions of young adult females living in Transbaikal region: a 10-year trend

The design of the research: two cross-sectional cohort studies with 10-year interval. The study included young adult females, 18-25 years of age: 209 women from Buryat population (in 2005 - 100, in 2015 - 109 persons) and 207 women from Russian population (in 2005 - 100, in 2015 -107 females). We found some positive trends in reproductive paradigm and gender behavior: relatively stable age of sexual debut, increasing role of health workers in young people reproductive education, a change of orientation in reproductive paradigm towards the model of multiple children family. The number of Orthodox believers significantly increased in Russian subpopulation

Obstetric and perinatal outcomes of monochorionic pregnancy

The objective. We aimed to study obstetric and perinatal outcomes in multiple pregnancies, depending on the type of choriality. Materials and methods. We used a retrospective analysis of the birth histories. 174 women with spontaneously occurring multiple pregnancies were involved in the study. There were 50 women with monochorionic placentation and 120 women with a dichorionic type of placentation. We analyzed the course of pregnancy, parturition and perinatal outcomes in these patients. The data were processed using parametric and nonparametric statistics. Results. Mean age of women was comparable and amounted to 28.5 ± 5.4 in women with monochorionic pregnancy and 29.4 ± 5.1 with dichorionic pregnancy. Both groups were comparable in social status, place of residence and parity. The risk of placental disorders (OR 2.9; 95% CI 1.4-5.7), fetal growth retardation (OR 2.4; 95% CI 1.1-5.4), gestational diabetes (Or 4,24; 95% CI 1.5-11.7), premature birth (OR 2.3; 95% CI 1.3-3.9), premature delivery at 34-36 weeks (OR 2.7; 95% CI 1.4-5.3), operative parturitions (OR 3.54; 95% CI 1.4-8.4), discordance of fetuses (OR 3.2; 95% CI 1.5-7.1) were higher in monochorionic multiple pregnancy. Prematurity (ОR 4.6; 95% CI 2.8-7.4) and low weight by gestational age (ОR 2.0; 95% CI 1,1-3.5) were the leading diagnosis in newborns who were born from monochorionic pregnancy. Conclusions. It is necessary to continue researches on this problem and develop guidelines for the management of women with monochorionic and dichorionic forms of placentation

Catamnesis of children from mothers who had A(H1N1)pdm09 influenza during pregnancy

The aim of this study was to assess 5-years catamnesis of children from mothers who had A(H1N1)pdm09 influenza during pregnancy. The design of the research: cohort cross-sectional retrospective "case - control" study. The study group included 227 children of mothers who had A(H1N1)pdm09 influenza during pregnancy, and the control group was consisted of 227 children whose mothers didn't have A(H1N1)pdm09 influenza in epidemic period during pregnancy. It was shown that 11,9 % of children born to mothers with influenza infection during pregnancy vs 1,8 % of children of the control group to 5-year age formed a cohort of patients with recurrent respiratory tract infections (p < 0,001). Acute respiratory infections were complicated by pneumonia in 15,4 % of study group children vs 8,8 % of children in the comparison group (p = 0,044). We founded a significant association between maternity A(H1N1)pdm09 influenza during 1st and 2nd trimesters of gestation and increased frequency of asthma in their children

PREVALENCE AND CHARACTERISTICS OF INFERTILITY IN YOUNG WOMEN OF REPRODUCTIVE AGE LIVING IN ZABAYKALSKY DISTRICT

We conducted epidemiological research of WHO record for the estimation of prevalence and characteristics of infertility in young women living in Zabaykalsky District. The research included 2932 women of 18-35 years, 731 of them had infertility. Frequency of infertility exceeds 15% critical level, determined by WHO, and reaches 24,9 % (22,3 % - in town, 25,8 % - in countryside). Secondary infertility appears more often that primary one (54,2 % vs 45,8 %). 44,0 % of young infertile women don't plan pregnancy

Associative connection of infectious and inflammatory diseases in pregnancy and severe preeclampsia

Materials and methods. This retrospective case-control study enrolled 50 women with severe preeclampsia and 50 control women with spontaneous singleton pregnancy. Median age of women ranged from 20 to 35 years. All women did not have a history of hypertension, autoimmune, metabolic, renal, or cardiac diseases, and preeclampsia before this pregnancy. We have analyzed χ2, odds ratio (OR) and its 95% confidence intervals (95% Cl). Results. We found significant association between maternal systemic infectious and severe preeclampsia (OR = 49.6; 95% Cl 13.05-188.64). The risk of severe preeclampsia were significantly lower in patients with local infections of the lower genital tract (OR = 4.5; 95% Cl 1.49-6.71). Asymptomatic bacteriuria is associated with the highest risk of severe preeclampsia (OR = 17.0; 95% Cl 4.66-61.81). Acute gravidarum pyelonephritis showed lower association with severe preeclampsia (OR = 5.4; 95% Cl 1.69-10.54). We did not observe increased risk of severe preeclampsia with acute respiratory infections (OR = 2.0; 95% Cl 0.71-4.69). Acute non-specific bacterial vaginitis and acute candidiasis vulvovaginitis were found to be risk factors of severe preeclampsia (OR = 6.7; 95% Cl 1.90-11.02 and OR = 4.3; 95% Cl 1.45-9.99 respectively). Cytomegalovirus infection (2 %), toxoplasmosis (2 %), Chlamydia trachomatis cervicitis (4 %), acute Trichomonas colpitis (2 %) and bacterial vaginosis (4 %) were found only in patients with severe preeclampsia. Conclusion. Our data support that acute maternal infection is associated with an increased risk of severe preeclampsia in healthy women with singleton pregnancy. Systemic inflammatory response might be the main potential mechanisms related to infections and enhanced development of severe preeclampsia. Further research is required to elucidate the underlying mechanism of this association