Immuno oriented therapy for mandible fractures in patients at high risk of developing inflammatory complications

Comparative clinical and immunological analysis of treatment of 49 patients with fractures of the mandible, receiving traditional therapy and treatment with use of immumomodulator leukinferon is carried out in this work. The results of the study demonstrate, that use of immunocorrection with leukinferon gives high immunological effect in comparison with traditional patients treatment. Positive dynamics of immunological parameters changes at patients is closely correlates with current of a clinical state in posttraumatic period. Use of leukinferon in complex therapy at patients with fracture of the mandible with high risk of inflammatory complications development allows to improve a condition of patients in shorter period and to warn inflammatory complications development

MODERN TECHNIQUES FOR FACE AND NECK PHLEGMONS TREATMENT

Aim. In the course of this study we carried out the analysis of clinical course features and assessment of microbiological structure of the wound surface in patients with face and neck phlegmons. The etiologic cause of the disease may be hemolytic streptococcus, different types of staphylococcus, mixed flora and anaerobic bacteria.Materials and methods. All patients required urgent surgical intervention: wide opening, drainage of cellular spaces with the subsequent irrigation with antiseptic solutions with the application of a combination of wound coverings "Aquacel Ag + Hydrofiber dressing", "Aquacel Ag Foam Hydrofiber dressing" and "Granuflex" (ConvaTec, the USA) with proper antibacterial therapy.Results. Comparison of clinical observations (favorable course of inflammatory process) and obtained microbiological assessment (quicker decrease of microbial content in the wound) confirms validity, high efficiency of wound covering application and clear advantage in comparison with traditional gauze bandages.Conclusion. The analysis of the causes of phlegmon on the face and neck over the past 5 years has shown a significant increase in the number of patients with traumatic, tonsilogenous and odontogenic phlegmons of the face and neck. The modern high-efficient method of local treatment with the use of wound coverings combinations makes it possible to suppress the purulent-inflammatory process at the early stage, to put the secondary stitches and shorten the period of treatment of patients

CLINICAL AND IMMUNOLOGICAL LEUKINFERON EVALUATION IN COMPLEX TREATMENT OF PATIENTS WITH MAXILLOFACIAL PHLEGMONS

In the present study we investigated the clinical and immunological evaluation of inclusion into medical complex in phlegmon of the maxillofacial region leukinferon immunomodulatory drug. The study included 100 patients with phlegmon of the maxillofacial region, randomized into 2 groups: I group consisted of 50 people who received conventional treatment; II group consisted of 50 people, in a comprehensive treatment that was included leukinferon. The data on the marked immunomodulatory effect on neutrophil granulocytes leukinferon system, as well as cell-mediated immunity. These effects provide a rapid withdrawal of patients from the state of secondary immune deficiency. Clinically, patients of group II marked a more effective relief of endogenous intoxication, shortening wound cleansing, shortening imposition of secondary sutures and overall duration of treatment in the hospital compared with patients in group I