Identification and safety effects of road user related measures. Deliverable 4.2 of the H2020 project SafetyCube

Safety CaUsation, Benefits and Efficiency (SafetyCube) is a European Commission supported Horizon 2020 project with the objective of developing an innovative road safety Decision Support System (DSS). The DSS will enable policy-makers and stakeholders to select and implement the most appropriate strategies, measures, and cost-effective approaches to reduce casualties of all road user types and all severities. This document is the second deliverable (4.2) of work package 4, which is dedicated to identifying and assessing road safety measures related to road users in terms of their effectiveness. The focus of deliverable 4.2 is on the identification and assessment of countermeasures and describes the corresponding operational procedure and outcomes. Measures which intend to increase road safety of all kind of road user groups have been considered [...continues]

Identification of safety effects of infrastructure related measures, Deliverable 5.2 of the H2020 project SafetyCube

Identification of safety effects of infrastructure related measures, Deliverable 5.2 of the H2020 project SafetyCub

Inventory of assessed infrastructure risk factors and measures, Deliverable 5.4 of the H2020 project SafetyCube

Inventory of assessed infrastructure risk factors and measures, Deliverable 5.4 of the H2020 project SafetyCub

Cattle Feeding and Resting Patterns in a Foothills Riparian Zone

Cattle impact on riparian areas is dependent upon both their behavior and utilization of streamside vegetation. Development of grazing strategies for riparian environments would be enhanced by an understanding of cattle behavior in riparian and adjacent uplands. Results of a 2-year behavior study indicate that a seasonal trend in cattle use of riparian and upland areas exists. Unless low precipitation limited upland forage quality/production, cattle spent a significant (P0.50) in the amount of time spent resting in either zone. Significant differences (P<0.05) occurred only when adverse weather conditions caused cattle to seek shelter in the riparian zone. Because cattle spend a disproportionate amount of their feeding time in the riparian zone during late summer and early fall, impacts could be limited by basing stocking rates for this period only on forage available in the riparian zone.This material was digitized as part of a cooperative project between the Society for Range Management and the University of Arizona Libraries.The Journal of Range Management archives are made available by the Society for Range Management and the University of Arizona Libraries. Contact [email protected] for further information.Migrated from OJS platform August 202

Distribution and amount of cathepsin B in gentamicin-induced acute kidney injury in rats

The aim of our study was to investigate how the distribution and amount of cathepsin B change during acute kidney injury. The research was done on a rat model of acute kidney injury that was induced by nephrotoxic antibiotic gentamicin. Gentamicin was injected at a dose of 40 mg/kg body weight (the first treated group) and 80 mg/kg body weight (the second treated group) for 14 days. Control groups received injections of physiological saline only. One day after the last injection, animals were euthanized, dissected and kidney samples were taken and fixed in 10% buffered formalin. Tissue sections were stained with haematoxylin and eosin, periodic Acid Schiff (PAS) and Oil-red-O. Immunohistochemistry was used for the demonstration of cathepsin B. Vacuolar degeneration of the proximal convoluted tubules was the most prominent pathologic lesion found in the first treated group, while necrosis prevailed in the second treated group in the same localisation. In both treated groups significantly weaker immunohistochemical reaction for cathepsin B was noticed in the proximal convoluted tubules in comparison to the control groups (P 0.05), as well. However, more numerous cathepsin B-positive large granules appeared in the proximal straight tubules of the second treated group then in the second control group (P < 0.05). We can conclude that the amount of cathepsin B in the affected proximal convoluted tubules significantly decreases along the increased severity of the histopathological lesions of the proximal convoluted tubuls, the amount of enzyme in the well preserved proximal straight tubules increases and more cathepsin B-positive large granules appear in the cytoplasm

T-3 and T-4 profile after TRH stimulation in growing Lipizzaner foals

Seven growing foals of Lipizzaner breed participated in a 12 months nutritional trial. The diets of the group of foals and mares consisted of normal local Karst hay plus grain superconcentrate mixture. During the first year of life, every three months TRH stimulation test (0.4 mg iv per animal) was performed. The effect of TRH on Lipizzaner foals thyroid function was determined by assesment of plasma thyroxin (T-4) and 3,5,3-triiodothyronine (T-3) before and after TIW administration. TRH was administered iv to 7 Lipizzaner foals at dose 0,4 mg/bwt. Plasma T-3 and T-4 concentration were determined before and 1, 3.5 and 4 hours after TRH administration. Plasma baseline values of T-3 and T-4 in foals at the age of 40 to 111 days were significantly different (p<0.001) from baseline values obtained in foals aged 136 to 207, 220 to 291 and foals aged from 319 to 390 days respectively. Plasma T-3 concentration increased from a basal concentration (0.41-1.55 nmol/L) to peak value (1.16-3.12 nmol/L) during four TRH stimulation tests. The highest T-3 response was observed in the youngest foals at the age of 40 to 111 days. Plasma T-4 concentration increased significantly after TRH stimulation 3.5 hours at the age of 40 to 111 days. Plasma T-4 peak concentration differed significantly (p<0,05) between foals aged 40 to 111 days and those aged 319 to 390 days. The highest T-4 response was also detected in the youngest foals at the age of 40 to 111 days. Results indicate the influence of age on T-3 and T-4 basal and response values in Lipizzaner foals