СЛУЧАЙ ТЯЖЕЛОГО ОСЛОЖНЕННОГО ТЕЧЕНИЯ ТЕНИАРИНХОЗА С АТИПИЧНОЙ ЛОКАЛИЗАЦИЕЙ ГЕЛЬМИНТА

Documented case of the clinical observations of the complicatedcourse of beef tapeworm infection (Taenia saginata) have a child 17  years of age. Three years ago, the patient first noticed the active  isolation of the cuttings from the anus. Other clinical symptoms were absent and the disease was latent. At the end of may 2017,  symptoms of an acute abdomen developed and an appendectomy  was performed on 03.06.2017. Diagnosis after surgery: acute  gangrenous perforative appendicitis, periappendicular abscess,  diffuse purulent peritonitis. 07.06.2017 was a single vomiting. In the vomit seen the segments of the flat worm. 09.06.2017,  segments of worms found in the feces. They were identified as  arthropods of Taenia saginata. From 14.06.2017 the patient’s  condition worsened, the temperature increased, there were pains in  the left half of the chest. In the following days the condition remained grave. According to CT (from 19.06.2017) helminth was determined in the  lumen of the left lower salt bronchus. Bronchoscopy was performed  (21.06.2017), which reduced the presence of signs of inflammation  of the left lower salt bronchus. Worms are not detected. Sputum  sowing was performed, but sputum microscopy was not carried out.  Ultrasound (23.06.2017) showed the presence of fluid in the left  pleural cavity. Puncture was performed and 70 ml of serous fluid was obtained. In the future, double-prosodical puncture which was obtained 600 and 500 ml of a yellow viscous exudate. On  29.06.2017, teniid eggs were found in sputum. Praziquantelum is  prescribed 25 mg / kg once. On 04.07.2017, the fourth puncture of  the pleural cavity was performed, 200 ml of light yellow effusion was obtained. In the days following the symptoms of pleurisy had disappeared and 10.07.2018, came recovery. Lung damage, which  developed as a result of aspiration of the arthroplasty Taenia  saginata was accompanied by a  rare dry cough and moderate  severe intoxication syndrome. The severity of the patient’s condition  was determined by severe respiratory failure and pain. Auscultation  of the wheezing was not. Over the lesion was sharply pronounced  weakened breathing. In the peripheral blood was determined by high ESR, moderate leukocytosis and no eosinophilia.Подробно описан клинический случай осложненного течения тениаринхоза (Taenia saginata)  у ребенка 17 лет. Три года назад пациент впервые заметил активное выделение члеников  из анального отверстия. Другие клинические симптомы отсутствовали, и заболевание  протекало латентно. В конце мая 2017 г. развились симптомы острого живота, 03.06.2017 г.  выполнена аппендектомия. Диагноз после операции: острый гангренозный перфоративный  аппендицит, периаппендикулярный абсцесс, диффузный гнойный перитонит. 07.06.2017 г.  была однократная рвота. В рвотных массах замечены членики плоского червя. 09.06.2017 г. членики гельминта обнаружены в фекалиях. Они были идентифицированы как членики  Taenia saginata. С 14.06.2017 г. состояние больного ухудшилось, повысилась температура,  появились боли в левой половине грудной клетки. В последующие дни состояние оставалось тяжелым. По данным КТ (от 19.06.2017 г.) гельминт определялся в просвете левого  нижнедолевого бронха. Выполнена бронхоскопия (21.06.2017 г.), которая установила наличие признаков воспаления левого нижнедолевого бронха. Гельминт не обнаружен. Выполнен посев мокроты, но микроскопия мокроты не проводилась. УЗИ (23.06.2017 г.)  показало наличие жидкости в левой плевральной полости. Проведена пункция, получено 70 мл серозной жидкости. В дальнейшем дважды проводилась пункция, в результате чего было получено 600 и 500 мл желтого вязкого экссудата. 29.06.2017 г. в мокроте были  обнаружены яйца тениид. Назначен Praziquantelum 25 мг/кг однократно. 04.07.2017 г. проведена четвертая пункция плевральной полости, получено 200 мл светло-желтого  выпота. В последующие дни симптомы плеврита исчезли, 10.07.2017 г. наступило выздоровление.  Поражение легких, которое развилось в результате аспирации  членика Taenia saginata, сопровождалось редким сухим кашлем и умерено выраженным  синдромом интоксикации. При этом тяжесть состояния пациента определялась выраженной  дыхательной недостаточностью и болевым синдром. При аускультации хрипов не было. Над  очагом поражения было резко выраженное ослабленное дыхание. В периферической крови  определялась высокая СОЭ при умеренном лейкоцитозе и отсутствии эозинофилии

The territory of advancing socio-economic development as a factor of development of the territory and attractions for the resident

The article provides analysis of the terminology of areas of advancing socio-economic development, legal support of creation and functioning of areas of advancing socio-economic development. The dynamics of the practical implementation of areas of advancing socio-economic development in the regions of Russia. The analysis highlighted the benefits of creating such zones for the activities of residents and for development of territories as a whole

CORRECTION OF THROMBOCYTOPOIESIS IN RATS WITH WALKER-256 CARCINOMA USING AN ANTIOXIDANT SUPPLEMENT IN THE SETTING OF CYTOSTATICS

In this study, we've evaluated the myelotoxic effect of treating Walker-256 carcinoma with cytostatics, followed by correction of thrombocytopenia with liposomal and liposome-free mexidol. The study included 60 rats, which, depending on the type of treatment, were divided into 5 groups. We recorded the greatest increase in the number of platelets on the background of liposomal mexidol both on the 3rd and 7th day after the start of chemotherapy. At the end of the monitoring, the myeloprotective effect was 30% higher in the liposomal mexidol compared to its non-liposomal form. CONCLUSION: Activation of thrombocytopoiesis on the background of cytostatic therapy helps to reduce the complications related to the use of chemotherapy

A case of severe complicated course of Taenia saginata with atypical localization of the helminth

Documented case of the clinical observations of the complicatedcourse of beef tapeworm infection (Taenia saginata) have a child 17  years of age. Three years ago, the patient first noticed the active  isolation of the cuttings from the anus. Other clinical symptoms were absent and the disease was latent. At the end of may 2017,  symptoms of an acute abdomen developed and an appendectomy  was performed on 03.06.2017. Diagnosis after surgery: acute  gangrenous perforative appendicitis, periappendicular abscess,  diffuse purulent peritonitis. 07.06.2017 was a single vomiting. In the vomit seen the segments of the flat worm. 09.06.2017,  segments of worms found in the feces. They were identified as  arthropods of Taenia saginata. From 14.06.2017 the patient’s  condition worsened, the temperature increased, there were pains in  the left half of the chest. In the following days the condition remained grave. According to CT (from 19.06.2017) helminth was determined in the  lumen of the left lower salt bronchus. Bronchoscopy was performed  (21.06.2017), which reduced the presence of signs of inflammation  of the left lower salt bronchus. Worms are not detected. Sputum  sowing was performed, but sputum microscopy was not carried out.  Ultrasound (23.06.2017) showed the presence of fluid in the left  pleural cavity. Puncture was performed and 70 ml of serous fluid was obtained. In the future, double-prosodical puncture which was obtained 600 and 500 ml of a yellow viscous exudate. On  29.06.2017, teniid eggs were found in sputum. Praziquantelum is  prescribed 25 mg / kg once. On 04.07.2017, the fourth puncture of  the pleural cavity was performed, 200 ml of light yellow effusion was obtained. In the days following the symptoms of pleurisy had disappeared and 10.07.2018, came recovery. Lung damage, which  developed as a result of aspiration of the arthroplasty Taenia  saginata was accompanied by a  rare dry cough and moderate  severe intoxication syndrome. The severity of the patient’s condition  was determined by severe respiratory failure and pain. Auscultation  of the wheezing was not. Over the lesion was sharply pronounced  weakened breathing. In the peripheral blood was determined by high ESR, moderate leukocytosis and no eosinophilia