425 research outputs found

    Integrative frontiers in environmental policy theory and research

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    Environmental policy research continues to advance toward a more Kuhnian “normal” science where theory and empirical tools are brought to bear on real-world policy systems to better understand social processes and determine the context in which policies work best. Traditional environmental policy tools now involve more flexible market-based instruments, voluntary agreements, and information provision tools like ecolabels and sustainability indicators. Policy process theories continue to be refined through hypothesis testing and are evolving into more integrative and multidisciplinary frameworks. Interdisciplinary methods are also being employed to better measure and analyze environmental outcomes, which has always been a major challenge in environmental policy research. These research tools are being explored in emerging policy approaches like collaborative partnerships and with novel environmental issues like climate change adaptation, pharmaceuticals and personal care products, and nanotechnology

    How limiting factors drive agricultural adaptation to climate change.

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    Consensus is growing that agriculture is vulnerable to climate change and adaptation responses are necessary to minimize impacts. Nonetheless, the diversity of potential impacts, agro-ecological contexts and regional capacity for change make understanding adaptation behaviors challenging and ensure that climate change adaptation will not be the same across all contexts. Considering this heterogeneity, this paper aims to develop a theoretical approach to connect agro-ecosystem diversity with farmer decision-making in the context of agricultural adaptation to climate change. We combine the ecological principle of Liebig’s Law of the Minimum with the Psychological Distance Theory to suggest how adaptation behaviors vary across regional contexts. We argue with our limiting factors hypothesis that limiting factors within a farm system (water or temperature impacts) influence the adoption of adaptation practices differently across regions and farm systems. Limiting factors varied across farm systems and regions, based on historical climate changes, agro-ecological contexts, infrastructure and adaptation capacity. Using farmer survey data from New Zealand we show that limiting factors mediate the effect of past climate experiences on the adoption of adaptation strategies differently in two regions with water acting as a limiting factor in Hawke’s Bay and water and temperature as a limiting factor in Marlborough. This suggests that farmers perceive and respond to climate change in part due to their personal experiences with climate change and the limiting factors within their system. Such results are relevant for the development of regional adaptation strategies, effective policies and targeted climate change communication

    Extension 3.0: Managing Agricultural Knowledge Systems in the Network Age

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    This paper develops the idea of “Extension 3.0” as an approach to agricultural extension that capitalizes on the network structure of local agricultural knowledge systems. Over the last century, agricultural knowledge systems have evolved into networks of widely distributed actors with a diversity of specializations and expertise. Agricultural extension programs need to manage these networks in ways that maximize the synergy between experiential, technical, and social learning. Using empirical research from California farmers, we highlight the structure of these networks within and across contexts, and the importance of boundary-spanning relationships. We provide some initial recommendations about actions needed to realize the goal of Extension 3.0, which is to deliver relevant agricultural knowledge to the right people, at the right time and plac

    Perceptions and responses to climate policy risks among California farmers

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    This paper considers how farmers perceive and respond to climate change policy risks, and suggests that understanding these risk responses is as important as understanding responses to biophysical climate change impacts. Based on a survey of 162 farmers in California, we test three hypotheses regarding climate policy risk: (1) that perceived climate change risks will have a direct impact on farmer\u27s responses to climate policy risks, (2) that previous climate change experiences will influence farmer\u27s climate change perceptions and climate policy risk responses, and (3) that past experiences with environmental policies will more strongly affect a farmer\u27s climate change beliefs, risks, and climate policy risk responses. Using a structural equation model we find support for all three hypotheses and furthermore show that farmers’ negative past policy experiences do not make them less likely to respond to climate policy risks through participation in a government incentive program. We discuss how future research and climate policies can be structured to garner greater agricultural participation. This work highlights that understanding climate policy risk responses and other social, economic and policy perspectives is a vital component of understanding climate change beliefs, risks and behaviors and should be more thoroughly considered in future work

    How context can impact clinical trials : a multi-country qualitative case study comparison of diagnostic biomarker test interventions

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    Background Context matters for the successful implementation of medical interventions, but its role remains surprisingly understudied. Against the backdrop of antimicrobial resistance, a global health priority, we investigated the introduction of a rapid diagnostic biomarker test (C-reactive protein, or CRP) to guide antibiotic prescriptions in outpatient settings and asked, “Which factors account for cross-country variations in the effectiveness of CRP biomarker test interventions?” Methods We conducted a cross-case comparison of CRP point-of-care test trials across Yangon (Myanmar), Chiang Rai (Thailand), and Hanoi (Vietnam). Cross-sectional qualitative data were originally collected as part of each clinical trial to broaden their evidence base and help explain their respective results. We synthesised these data and developed a large qualitative data set comprising 130 interview and focus group participants (healthcare workers and patients) and nearly one million words worth of transcripts and interview notes. Inductive thematic analysis was used to identify contextual factors and compare them across the three case studies. As clinical trial outcomes, we considered patients’ and healthcare workers’ adherence to the biomarker test results, and patient exclusion to gauge the potential “impact” of CRP point-of-care testing on the population level. Results We identified three principal domains of contextual influences on intervention effectiveness. First, perceived risks from infectious diseases influenced the adherence of the clinical users (nurses, doctors). Second, the health system context related to all three intervention outcomes (via the health policy and antibiotic policy environment, and via health system structures and the ensuing utilisation patterns). Third, the demand-side context influenced the patient adherence to CRP point-of-care tests and exclusion from the intervention through variations in local healthcare-seeking behaviours, popular conceptions of illness and medicine, and the resulting utilisation of the health system. Conclusions Our study underscored the importance of contextual variation for the interpretation of clinical trial findings. Further research should investigate the range and magnitude of contextual effects on trial outcomes through meta-analyses of large sets of clinical trials. For this to be possible, clinical trials should collect qualitative and quantitative contextual information for instance on their disease, health system, and demand-side environment. Trial registration: ClinicalTrials.gov Identifiers NCT02758821 and NCT01918579

    Threshold Laws for the Break-up of Atomic Particles into Several Charged Fragments

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    The processes with three or more charged particles in the final state exhibit particular threshold behavior, as inferred by the famous Wannier law for (2e + ion) system. We formulate a general solution which determines the threshold behavior of the cross section for multiple fragmentation. Applications to several systems of particular importance with three, four and five leptons (electrons and positrons) in the field of charged core; and two pairs of identical particles with opposite charges are presented. New threshold exponents for these systems are predicted, while some previously suggested threshold laws are revised.Comment: 40 pages, Revtex, scheduled for the July issue of Phys.Rev.A (1998

    Point-of-care C-reactive protein testing to reduce inappropriate use of antibiotics for non-severe acute respiratory infections in Vietnamese primary health care: a randomised controlled trial

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    Background Inappropriate antibiotic use for acute respiratory tract infections is common in primary health care, but distinguishing serious from self-limiting infections is diffi cult, particularly in low-resource settings. We assessed whether C-reactive protein point-of-care testing can safely reduce antibiotic use in patients with non-severe acute respiratory tract infections in Vietnam. Method We did a multicentre open-label randomised controlled trial in ten primary health-care centres in northern Vietnam. Patients aged 1–65 years with at least one focal and one systemic symptom of acute respiratory tract infection were assigned 1:1 to receive either C-reactive protein point-of-care testing or routine care, following which antibiotic prescribing decisions were made. Patients with severe acute respiratory tract infection were excluded. Enrolled patients were reassessed on day 3, 4, or 5, and on day 14 a structured telephone interview was done blind to the intervention. Randomised assignments were concealed from prescribers and patients but not masked as the test result was used to assist treatment decisions. The primary outcome was antibiotic use within 14 days of follow-up. All analyses were prespecifi ed in the protocol and the statistical analysis plan. All analyses were done on the intention-totreat population and the analysis of the primary endpoint was repeated in the per-protocol population. This trial is registered under number NCT01918579. Findings Between March 17, 2014, and July 3, 2015, 2037 patients (1028 children and 1009 adults) were enrolled and randomised. One adult patient withdrew immediately after randomisation. 1017 patients were assigned to receive C-reactive protein point-of-care testing, and 1019 patients were assigned to receive routine care. 115 patients in the C-reactive protein point-of-care group and 72 patients in the routine care group were excluded in the intention-to-treat analysis due to missing primary endpoint. The number of patients who used antibiotics within 14 days was 581 (64%) of 902 patients in the C-reactive protein group versus 738 (78%) of 947 patients in the control group (odds ratio [OR] 0·49, 95% CI 0·40–0·61; p<0·0001). Highly signifi cant diff erences were seen in both children and adults, with substantial heterogeneity of the intervention eff ect across the 10 sites (I²=84%, 95% CI 66–96). 140 patients in the C-reactive protein group and 137 patients in the routine care group missed the urine test on day 3, 4, or 5. Antibiotic activity in urine on day 3, 4, or 5 was found in 267 (30%) of 877 patients in the C-reactive protein group versus 314 (36%) of 882 patients in the routine treatment group (OR 0·78, 95% CI 0·63–0·95; p=0·015). Time to resolution of symptoms was similar in both groups. Adverse events were rare, with no deaths and a total of 14 hospital admissions (six in the C-reactive protein group and eight in the control group). Interpretation C-reactive protein point-of-care testing reduced antibiotic use for non-severe acute respiratory tract infection without compromising patients’ recovery in primary health care in Vietnam. Health-care providers might have become familiar with the clinical picture of low C-reactive protein, leading to reduction in antibiotic prescribing in both groups, but this would have led to a reduction in observed eff ect, rather than overestimation. Qualitative analysis is needed to address diff erences in context in order to implement this strategy to improve rational antibiotic use for patients with acute respiratory infection in low-income and middle-income countries
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