The influence of nanoparticles on biological objects

The modem opportunities o f medical care are basing on usage of new methods of diagnostic and treatment, including nanotechnologies and nanoobjects in clinical medicine and pharmacology. The experiment was carried out on 58 rats. The nanoparticles of iron oxide were used intranasally and by application on skin in kind of suspension. The methods were used: light, transmission, electron, probe and scanning microscopy with microelement analysi

Issues in the study of utero-placental blood flow in severe gestosis

The complications of pregnancy, gestosis particularly, are still important aspects on the modern stage of development of obstetrics, as it influences on development of maternal and perinatal morbidity and mortality. One hundred and twenty-five patients with severe gestosis were studied. The conditions of myometrium, endometrium, placenta, umbilical chord as well as erythrocytes of maternal blood were explored with help of atomic power microscopy, light microscopy as well as electron microscop

Morphofunctional features of erythrocytes in oncourological patients

The malignant tumors are one of the most important problems of urology. The blood sampling was conducted before treatment for research of erythrocytes in patients with cancer of kidney (25 patients), bladder, prostate (25) and in healthy patients (10). The samples of tissue of damaged organs were taken during surgery. The samples were studied with help of raster and scanning electron microscopy with elemental analysis, atomic power microscopy and confocal microscop

Innovative methods of atomic force microscopy in oncology diagnostics

The purpose of this work is to study the morphological forms of erythrocytes, and also pathomorphological changes in prostate gland and kidneys with the use of atomic force microscopy (AFM) during oncological processes. Results: The decrease of discocytes was observed, and the number of transitional, pre-hemolytic and degenerative forms of erythrocytes increased. During the study of the external level of erythrocytes using AFM, it was established that the depth of the discocyte cavity counted by the study of a cell profile changed significantl

Pathomorphological indicators of endothelial - erythrocytic dysfunction in type I diabetes: from the period of reproduction to the elderly and senile age

The study proved that changes in carbohydrate metabolism in diabetes mellitus significantly affect the properties of the endothelial-erythrocytic system, and they can be diagnosed using various modern microscopy methods at an early stag

New phenomena in the clinical and morphological aspects of osteoporosis

The aim of this study is to compare the biochemical indexes of phosphorus-calcium (Ca) metabolism in patients with metabolic syndrome of 1–5 stages, associated with osteoporosis with morphological picture of bone tissue. Results: The results of the study of biochemical indexes of phosphorus-calcium (Ca) metabolism in patients with metabolic syndrome associated with osteoporosis were presented in the articl

Morphofunctional aspects of bone tissue at osteoporosis

At exploration of morphofunctional features of bone tissue at osteoporosis it was founded that the decreasing of total area of solid substance in bone tissue took place. In cancellous substance bone plates became perforated and thin, collapsed, forming large cavities. Trabecular lattice system became thin and partially interrupted. Trabeculae became thin, distance between them increased. Key words: osteoporosis, bone tissue, bone fracture, old ag

New aspects in the study of clinical and morphological new aspects in the study of blood in type II diabetes mellitus

The aim of the research was to study red blood cells in type II diabetes mellitus, both an independently occurring disease, and in combination with hypertension, using innovative research methods (atomic force and scanning electron microscopy with elemental analysis

New pathomorphological approaches to study of appendicitis in children

The modern setting of indications to surgical treatment of appendicitis is still complex problem in spite of reached success and wide usage of modern diagnostic methods. The researches of erythrocytes of venous blood of children with superficial (catarrhal) (10) and phlegmonic(destructive) (35) appendicitis were performed. The cells were explored with help of atomic power microscopy. The removed appendixes were explored with help of light microscopy, scanning probe microscopy as well as atomic power microscop

Pathomorphological aspects of thermal trauma

The majority of people face with unfavorable influence of thermal factors of environment. The thermal trauma can be a cause of injury and death of subjects. One hundred twenty rats were subjected to influence of temperature 28, 38, 48°С in duration of 5 min in thermal camera. Brain, liver, kidneys, heart, skeletal muscles were studied with help o f light, raster and scanning electron microscopy with elemental analysis. The overheating at 38°С leaded to formation of quick adaptation to heat, directed to preservation of transport and protidosynthetic functions, as well as to development of disadaptative processe