Changing the color of tooth enamel in the process of orthodontic treatment

Teeth discoloration is a rare orthodontic complication during orthodontic treatment. We present 6-year clinical observation conducted from January 2010 till December 2016. The eighteen orthodontic patients with teeth discoloration took part in this observation. Four patients were excluded from the observation as their teeth discoloration were under orthodontic treatment. During clinical observation period, discovered discoloration was evaluated as «improved» in 4 out of 14 teeth (28.5 %), as «maintained» in 10 teeth (71.4 %). Electroodontodiagnosis conducted during the initial detection period of discoloration showed 14.3 % positivity, which improved to 21.4 % at the final follow-up. The radiological pictures of the teeth showed no abnormalities. Thus, we can assume that teeth with one wide long root canal are more prone to damage to the pulp blood supply. Discoloration is also more frequent in the maxillary teeth, possibly due to the overjet relationship, which may increase susceptibility to trauma in the maxillary teeth. We should keep dynamical observation in the orthodontic practice as teeth color could reverse to the initial without additional interference. 1f discoloration does not improve even after sufficient observation, it is necessary to start orthodontic treatment (endodontic, prosthetic) or bleaching. A patient should be informed that discoloration does not always indicate devitalization or pulp necrosis. Instead of "devitalization" or "pulp necrosis" we recommend to use the term "discoloration"

Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality

Aim: to establish a link between the level of folic acid, vitamin D and iodine consumption, and infant and perinatal mortality, morbidity of childhood tuberculosis in the Irkutsk region. Consumption of folate in the form of a single-agent preparation increased 3 times in 5 years. Consumption of folic acid in women at the stage of preconception and pregnancy affected the reduction of perinatal (R = -0.9; p = 0.016) and infant (R = -0.89; p = 0.04) mortality, including neonatal (R = -0.89; p = 0.039). Preventive supplementation of vitamin D of people in the region over the past 5years has increased by 70 %, and infant mortality fell by 35.5 %. Infant (R = -0.94; p = 0.01) and especially post-neonatal (R = -0.97; p = 0.004) mortality are controllable and depend on the prevention of hypovitaminosis D. The understanding of the role of vitamin D in triggering the synthesis of the antimicrobial peptide cathelicidin opens prospects for using it as a medicine for prevention and treatment of childhood tuberculosis. The incidence of pediatric tuberculosis in the region during this period decreased by 46 % (R = -0.95; p = 0.01). Correction of iodine deficiency in pregnant women and children caused the reduction of perinatal (R = -0.99; p = 0.07), early neonatal (R = -0.99; p = 0.05), neonatal (R = -0.98; p = 0.06) and post-neonatal (R = -0.99; p = 0.002) infant mortality

HYGIENIC VALUE OF VITAMIN D DEFICIENCY IN IRKUTSK REGION AND WAYS OF ITS PREVENTION

The status of vitamin D in the population of Irkutsk region has been determined by the contents of 25(OH)D3 in blood serum of268 people of different age. The highest rates were found in children - 37,78 ± 1,74 ng/ml. In men the level of activity of 25(OH)D3 was equal to 24,64 ± 2,33 ng/ml, in women up to 70years - 21,22 ± 0,85, older than 70 years -15,13 ± 2,24 ng/ml. The lowest rates are found in children with celiac disease -13,43 ± 2,14. More than 60 % of the population suffer from vitamin D deficiency. Yet wide-scale preventive measures are not possible due to limited range offortified food in the trade network

Appropriate prevention of vitamin D deficiency in the population of the Irkutsk region

Purpose of the study. To determine the influence of climatic and geographical factors of the Irkutsk region on the risk of hypovitaminosis D in children and adults. Patients and methods. The contents of 25(OH)D-3 in the blood of children and adults (3261 samples) were evaluated. The materials were obtained in the Diagnostic Center of the region and the InVitro laboratory. Results of monitoring of ultraviolet radiation and precipitation in the Irkutsk region for 2014-2015 were analyzed according to ground and satellite measurements. Results. The Irkutsk region is in the zone of ultraviolet insufficiency during the period from September-October to March-May. The status of the metabolite of vitamin D - 25(oH)D3 in the population of the region is low, especially in adolescents and people older than 70 years. 68 % of children have vitamin D deficiency. Activity of 25(oH)D3 depends on meteorological factors, especially the level of precipitation and the intake of vitamin D. For each geographical area of the region, time intervals were calculated for the formation of vitamin D in the skin under the influence of ultraviolet radiation and time intervals for the intake of vitamin D preparations. The exposure time in the sun was calculated for the formation of vitamin D for individuals with different skin phototypes, depending on the degree of its openness