Esthesioneuroblastoma: clinical course, long-term results of treatment

This rare tumor from a group of neuroendocrine neoplasms was studied. The material for the study was the data of 78 patients with esthesioneuroblastoma who had been treated and followed up at the N.N. Blokhin Russian Cancer Research Center in the period 1965 to 2014. Information on hospital statistics, clinical features, methods, and treatment results were presented. The possibilities of using the TNM classification for the nasal cavity, ethmoidal sinuses, and nasopharynx were assessed to determine the anatomic extent of primary tumor. The findings contribute to the solution of problems in the diagnosis and treatment of esthesioneuroblastoma at the present stage

USE OF PREDICTORS TO CHOOSE TREATMENT POLICY FOR THYROID CANCER

The paper analyzes the results of treatment in patients with papillary thyroid cancer, by applying a great deal of clinical material. Different prognostic factors have been studied for their influence on the survival of the patients after surgical treatment. The most optimal treatment policy is proposed to be defined for patients with this form of cancer on the basis of the association between the above factors

LONG-TERM RESULTS OF NASOPHARYNGEAL CARCINOMA TREATMENT (BASED ON THE ANALYSIS OF CASES FROM CANCER REGISTRY OF N.N. BLOKHIN RUSSIAN CANCER RESEARCH CENTER DURING 1980–2010)

Data on 573 patients with nasopharyngeal carcinoma registered for treatment in N.N.  Blokhin Russian Cancer Research Center in 1980–2010 was used for the analysis. The study revealed high rate of late-stage diagnosis of nasopharyngeal carcinoma (82.9 %), low cancer suspicion, poor diagnostics in general practice (73.2 %). Active screening for nasopharyngeal carcinoma is virtually absent in Russia. According to the study results, combined radiotherapy is an optimal method for nasopharyngeal cancer treatment; chemoradiotherapy with platinum drugs, doxorubicin, bleomycin combined with hyperfractionated radiotherapy is preferable for treatment of locally advanced and reginal tumors

A RARE CASE OF THYROID CANCER METASTASIS TO PARAPHARYNGEAL LYMPH NODES

The paper presents the specific features of the diagnosis and treatment of thyroid cancer metastases to parapharyngeal lymph nodes

SURGICAL TREATMENT FOR GENERALIZED SKIN CANCER OF THE FOREHEAD (2 CLINICAL CASES)

The paper outlines the possibilities of surgical treatment in patients with generalized skin cancer of the head and neck. The use of different types of free revascularized flaps can yield acceptable functional and cosmetic results

Osteosarcoma of the larynx: rare clinical case

We present a clinical case of osteosarcoma of the larynx. It is a rare and aggressive tumor characterized by frequent local recurrence and the appearance of distant metastases. This is the only one case of osteosarcoma of the larynx in N.N. Blokhin National Medical Research Center of Oncology for the period from 1988 to 2017