126 research outputs found
Estudo da influência do torque de inserção na resistência ao arrancamento dos parafusos pediculares
Successful outcome of six-level cervicothoracic corpectomy and circumferential reconstruction: case report and review of literature on multilevel cervicothoracic corpectomy
The authors report the successful outcome of a six-level corpectomy across the cervico-thoracic spine with circumferential reconstruction in a patient with extensive osteomyelitis of the cervical and upper thoracic spine. To the authors’ knowledge, this is the first report of a corpectomy extending across six levels of the cervico-thoracic spine. Clinical relevance: the authors recommend anterior cage and plate-assisted reconstruction and additional posterior instrumentation using modern spinal surgical techniques and implants
Surgical outcomes after instrumented lumbar surgery in patients of eighty years of age and older
Histomorphometric analysis of bone tissue repair in rabbits after insertion of titanium screws under different torque
The effects of anterior vacuum disc on surgical outcomes of degenerative versus spondylolytic spondylolisthesis: at a minimum two-year follow-up
Modeling functional cell types in spike train data.
A major goal of computational neuroscience is to build accurate models of the activity of neurons that can be used to interpret their function in circuits. Here, we explore using functional cell types to refine single-cell models by grouping them into functionally relevant classes. Formally, we define a hierarchical generative model for cell types, single-cell parameters, and neural responses, and then derive an expectation-maximization algorithm with variational inference that maximizes the likelihood of the neural recordings. We apply this "simultaneous" method to estimate cell types and fit single-cell models from simulated data, and find that it accurately recovers the ground truth parameters. We then apply our approach to in vitro neural recordings from neurons in mouse primary visual cortex, and find that it yields improved prediction of single-cell activity. We demonstrate that the discovered cell-type clusters are well separated and generalizable, and thus amenable to interpretation. We then compare discovered cluster memberships with locational, morphological, and transcriptomic data. Our findings reveal the potential to improve models of neural responses by explicitly allowing for shared functional properties across neurons
Refinement of interbody implant testing in goats: a surgical and morphometric rationale for selection of a cervical level
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