784 research outputs found

    Attitudes of Deaf and Hearing Adults in Israel Toward Deaf People’s Career Suitability

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    This study investigated the expressed attitudes of deaf adults as well as hearing parents and teachers of deaf children in Israel toward career choices for deaf and hearing people by asking the participants to rate the suitability of 14 professions for deaf and hearing people. The results, in general, were consistent with those of other studies in the United States, England, Italy, South Africa and India with hearing teachers and parents of deaf children, which indicated that the hearing status of imagined advisees selectively influenced attitudes toward the suitability of certain professions. Deaf adults in Israel gave significantly lower ratings for deaf advisees on 10 out of 14 professions and did not find any of the professions to be more suitable for a deaf advisee when compared to a hearing advisee. These results are in contrast to those found by Parasnis, Samar and Mandke (1996) with deaf adults in India. Implications of these findings are discussed

    Neutron-proton analyzing power at 12 MeV and inconsistencies in parametrizations of nucleon-nucleon data

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    We present the most accurate and complete data set for the analyzing power Ay(theta) in neutron-proton scattering. The experimental data were corrected for the effects of multiple scattering, both in the center detector and in the neutron detectors. The final data at En = 12.0 MeV deviate considerably from the predictions of nucleon-nucleon phase-shift analyses and potential models. The impact of the new data on the value of the charged pion-nucleon coupling constant is discussed in a model study.Comment: Six pages, four figures, one table, to be published in Physics Letters

    The presence of γ′ chain impairs fibrin polymerization

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    A fraction of fibrinogen molecules contain an alternatively spliced variant chain called γ’. Plasma levels of this variant have been associated with both myocardial infarction and venous thrombosis. Because clot structure has been associated with cardiovascular risk, we examined the effect of γ’ chain on clot structure

    Outdoor, Indoor, and Personal Exposure to VOCs in Children

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    We measured volatile organic compound (VOC) exposures in multiple locations for a diverse population of children who attended two inner-city schools in Minneapolis, Minnesota. Fifteen common VOCs were measured at four locations: outdoors (O), indoors at school (S), indoors at home (H), and in personal samples (P). Concentrations of most VOCs followed the general pattern O ≈ S < P ≤ H across the measured microenvironments. The S and O environments had the smallest and H the largest influence on personal exposure to most compounds. A time-weighted model of P exposure using all measured microenvironments and time–activity data provided little additional explanatory power beyond that provided by using the H measurement alone. Although H and P concentrations of most VOCs measured in this study were similar to or lower than levels measured in recent personal monitoring studies of adults and children in the United States, p-dichlorobenzene was the notable exception to this pattern, with upper-bound exposures more than 100 times greater than those found in other studies of children. Median and upper-bound H and P exposures were well above health benchmarks for several compounds, so outdoor measurements likely underestimate long-term health risks from children’s exposure to these compounds

    Intracellular origin and ultrastructure of platelet-derived microparticles

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    © 2017 International Society on Thrombosis and Haemostasis Essentials Platelet microparticles play a major role in pathologies, including hemostasis and thrombosis. Platelet microparticles have been analyzed and classified based on their ultrastructure. The structure and intracellular origin of microparticles depend on the cell-activating stimulus. Thrombin-treated platelets fall apart and form microparticles that contain cellular organelles. Summary: Background Platelet-derived microparticles comprise the major population of circulating blood microparticles that play an important role in hemostasis and thrombosis. Despite numerous studies on the (patho)physiological roles of platelet-derived microparticles, mechanisms of their formation and structural details remain largely unknown. Objectives Here we studied the formation, ultrastructure and composition of platelet-derived microparticles from isolated human platelets, either quiescent or stimulated with one of the following activators: arachidonic acid, ADP, collagen, thrombin or calcium ionophore A23187. Methods Using flow cytometry, transmission and scanning electron microscopy, we analyzed the intracellular origin, structural diversity and size distributions of the subcellular particles released from platelets. Results The structure, dimensions and intracellular origin of microparticles depend on the cell-activating stimulus. The main structural groups include a vesicle surrounded by one thin membrane or multivesicular structures. Thrombin, unlike other stimuli, induced formation of microparticles not only from the platelet plasma membrane and cytoplasm but also from intracellular structures. A fraction of these vesicular particles having an intracellular origin contained organelles, such as mitochondria, glycogen granules and vacuoles. The size of platelet-derived microparticles depended on the nature of the cell-activating stimulus. Conclusion The results obtained provide a structural basis for the qualitative differences of various platelet activators, for specific physiological and pathological effects of microparticles, and for development of advanced assays

    An updated analysis of NN elastic scattering data to 1.6 GeV

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    An energy-dependent and set of single-energy partial-wave analyses of NNNN elastic scattering data have been completed. The fit to 1.6~GeV has been supplemented with a low-energy analysis to 400 MeV. Using the low-energy fit, we study the sensitivity of our analysis to the choice of πNN\pi NN coupling constant. We also comment on the possibility of fitting npnp data alone. These results are compared with those found in the recent Nijmegen analyses. (Figures may be obtained from the authors upon request.)Comment: 17 pages of text, VPI-CAPS-7/
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