419 research outputs found
Rapid Aeroelastic Analysis of Blade Flutter in Turbomachines
The LINFLUX-AE computer code predicts flutter and forced responses of blades and vanes in turbomachines under subsonic, transonic, and supersonic flow conditions. The code solves the Euler equations of unsteady flow in a blade passage under the assumption that the blades vibrate harmonically at small amplitudes. The steady-state nonlinear Euler equations are solved by a separate program, then equations for unsteady flow components are obtained through linearization around the steady-state solution. A structural-dynamics analysis (see figure) is performed to determine the frequencies and mode shapes of blade vibrations, a preprocessor interpolates mode shapes from the structural-dynamics mesh onto the LINFLUX computational-fluid-dynamics mesh, and an interface code is used to convert the steady-state flow solution to a form required by LINFLUX. Then LINFLUX solves the linearized equations in the frequency domain to calculate the unsteady aerodynamic pressure distribution for a given vibration mode, frequency, and interblade phase angle. A post-processor uses the unsteady pressures to calculate generalized aerodynamic forces, response amplitudes, and eigenvalues (which determine the flutter frequency and damping). In comparison with the TURBO-AE aeroelastic-analysis code, which solves the equations in the time domain, LINFLUX-AE is 6 to 7 times faster
Unsteady transonic cascade fow with in-passage shock wave
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76409/1/AIAA-25179-720.pd
Predictive ability of an early diagnostic guess in patients presenting with chest pain; a longitudinal descriptive study
The intuitive early diagnostic guess could play an important role in reaching a final diagnosis. However, no study to date has attempted to quantify the importance of general practitioners' (GPs) ability to correctly appraise the origin of chest pain within the first minutes of an encounter.
The validation study was nested in a multicentre cohort study with a one year follow-up and included 626 successive patients who presented with chest pain and were attended by 58 GPs in Western Switzerland. The early diagnostic guess was assessed prior to a patient's history being taken by a GP and was then compared to a diagnosis of chest pain observed over the next year.
Using summary measures clustered at the GP's level, the early diagnostic guess was confirmed by further investigation in 51.0% (CI 95%; 49.4% to 52.5%) of patients presenting with chest pain. The early diagnostic guess was more accurate in patients with a life threatening illness (65.4%; CI 95% 64.5% to 66.3%) and in patients who did not feel anxious (62.9%; CI 95% 62.5% to 63.3%). The predictive abilities of an early diagnostic guess were consistent among GPs.
The GPs early diagnostic guess was correct in one out of two patients presenting with chest pain. The probability of a correct guess was higher in patients with a life-threatening illness and in patients not feeling anxious about their pain
A shallow earthquake swarm close to hydrocarbon activities: discriminating between natural and induced causes for the 2018–19 Surrey, UK earthquake sequence
Earthquakes induced by subsurface industrial activities are a globally emotive issue, with a growing catalogue of induced earthquake sequences. However, attempts at discriminating between natural and induced causes, particularly for anomalously shallow seismicity, can be challenging. An earthquake swarm during 2018–19 in south-east England with a maximum magnitude of ML 3.2 received great public and media attention because of its proximity to operating oilfields. It is therefore vital and timely to provide a detailed characterisation of the earthquake sequence at present, and to decide based on current evidence, whether the earthquakes were likely natural or induced. We detected 168 low-magnitude earthquakes and computed detailed source parameters of these events. Most earthquakes occurred at a shallow depth of 2.3 km, >1 km deeper than the geological formations targeted by the oilfields, and laterally >3 km away from the drill-sites. We combine the east-west trending cluster of the seismicity with 2-D seismic reflection profiles to find the causative fault system for the earthquakes. A b-value close to unity and strike-slip faulting mechanisms are consistent with tectonic reactivation along a pre-existing fault. Overall, we find no indicators in the earthquake parameters that would strongly suggest an induced source. Nor do we find any clear trends between seismicity and drilling activities based on operational logs provided by the operators. Injected volumes are near-zero and monthly production amounts are many orders of magnitude smaller than other reported cases of extraction-induced seismicity. On balance, and based on the available evidence, we find it currently unlikely that nearby industrial activities induced the seismic swarm. Most likely, the Surrey earthquakes offer a uniquely detailed insight into shallow seismicity within sedimentary basins. Nevertheless, self-reporting of injection and production times and volumes by operators, and the lack of easily- and publicly-available oilfield operational data continues to be a point of concern for local residents
Different atmospheric moisture divergence responses to extreme and moderate El Niños
On seasonal and inter-annual time scales, vertically integrated moisture divergence provides a useful measure of the tropical atmospheric hydrological cycle. It reflects the combined dynamical and thermodynamical effects, and is not subject to the limitations that afflict observations of evaporation minus precipitation. An empirical orthogonal function (EOF) analysis of the tropical Pacific moisture divergence fields calculated from the ERA-Interim reanalysis reveals the dominant effects of the El Niño-Southern Oscillation (ENSO) on inter-annual time scales. Two EOFs are necessary to capture the ENSO signature, and regression relationships between their Principal Components and indices of equatorial Pacific sea surface temperature (SST) demonstrate that the transition from strong La Niña through to extreme El Niño events is not a linear one. The largest deviation from linearity is for the strongest El Niños, and we interpret that this arises at least partly because the EOF analysis cannot easily separate different patterns of responses that are not orthogonal to each other. To overcome the orthogonality constraints, a self-organizing map (SOM) analysis of the same moisture divergence fields was performed. The SOM analysis captures the range of responses to ENSO, including the distinction between the moderate and strong El Niños identified by the EOF analysis. The work demonstrates the potential for the application of SOM to large scale climatic analysis, by virtue of its easier interpretation, relaxation of orthogonality constraints and its versatility for serving as an alternative classification method. Both the EOF and SOM analyses suggest a classification of “moderate” and “extreme” El Niños by their differences in the magnitudes of the hydrological cycle responses, spatial patterns and evolutionary paths. Classification from the moisture divergence point of view shows consistency with results based on other physical variables such as SST
Trends in monitoring of Australia’s threatened birds (1990–2020): Much improved but still inadequate
Monitoring is vital to conservation, enabling conservation scientists to detect population declines, identify threats and measure the effectiveness of interventions. However, not all threatened taxa are monitored, monitoring quality is variable, and the various components of monitoring are likely to differ in their rates of improvement over time. We assessed the presence of monitoring and monitoring quality, using a range of metrics, for all Australia’s threatened bird taxa from 1990 to 2020 (four assessments spanning 30 years). We used our assessments to understand decadal trends in the number of taxa monitored; monitoring quality; and the groups that conduct monitoring. The monitoring of Australia’s threatened birds has increased substantially since 1990, from 19% of taxa to 75% in 2020. Monitoring quality has also improved, with 24.1% of taxa assessed overall as ‘Good’ or ‘Very Good’ in 2020 (up from 4.8% in 1990). However, by 2020, most monitoring programmes still scored poorly for Data availability/reporting, Management linkage, Demographic data and Training/succession planning. In 2020, private individuals and governments accounted for 59% of monitoring contributions, with the greatest number of taxa monitored by private individuals (79 of 166 taxa assessed). Despite improvements in monitoring since 1990, only a minority of taxa had high-quality monitoring in the most recent assessment period. Monitoring is a powerful tool in conservation, justifying investment in improving how it is conducted. We draw on our results and examples of high-quality monitoring programmes to develop a set of priority actions to improve monitoring of Australia’s threatened birds
Sex/gender bias in the management of chest pain in ambulatory care.
Cardiovascular diseases (CVD) are the main cause of death worldwide and despite a higher prevalence in men, mortality from CVD is higher among women. Few studies have assessed sex differences in chest pain management in ambulatory care. The objective of this post hoc analysis of data from a prospective cohort study was to assess sex differences in the management of chest pain in ambulatory care.
We used data from the Thoracic Pain in Community cohort study that was realized in 58 primary care practices and one university ambulatory clinic in Switzerland.
In total, 672 consecutive patients aged over 16 years attending a primary care practice or ambulatory care clinic with a complaint of chest pain were included between February and June 2001. Their mean age was 55.2 years and 52.5% were women.
The main outcome was the proportion of patients referred to a cardiologist at 12 months follow-up. A panel of primary care physicians assessed the final diagnosis retained for chest pain at 12 months.
The prevalence of chest pain of cardiovascular origin (n = 108, 16.1%) was similar for men and women (17.5% vs 14.8%, respectively, p = 0.4). Men with chest pain were 2.5 times more likely to be referred to a cardiologist than women (16.6% vs 7.4%, odds ratio: 2.49, 95% confidence interval: 1.52-4.09). After adjustment for the patients' age and cardiovascular disease risk factors, the estimates did not significantly change (odds ratio: 2.30, 95% confidence interval: 1.30-3.78).
Although the same proportion of women and men present with a chest pain of cardiovascular origin in ambulatory care, there is a strong sex bias in their management. These data suggest that effort must be made to assure equity between men and women in medical care
The prognosis of allocentric and egocentric neglect : evidence from clinical scans
We contrasted the neuroanatomical substrates of sub-acute and chronic visuospatial deficits associated with different aspects of unilateral neglect using computed tomography scans acquired as part of routine clinical diagnosis. Voxel-wise statistical analyses were conducted on a group of 160 stroke patients scanned at a sub-acute stage. Lesion-deficit relationships were assessed across the whole brain, separately for grey and white matter. We assessed lesions that were associated with behavioural performance (i) at a sub-acute stage (within 3 months of the stroke) and (ii) at a chronic stage (after 9 months post stroke). Allocentric and egocentric neglect symptoms at the sub-acute stage were associated with lesions to dissociated regions within the frontal lobe, amongst other regions. However the frontal lesions were not associated with neglect at the chronic stage. On the other hand, lesions in the angular gyrus were associated with persistent allocentric neglect. In contrast, lesions within the superior temporal gyrus extending into the supramarginal gyrus, as well as lesions within the basal ganglia and insula, were associated with persistent egocentric neglect. Damage within the temporo-parietal junction was associated with both types of neglect at the sub-acute stage and 9 months later. Furthermore, white matter disconnections resulting from damage along the superior longitudinal fasciculus were associated with both types of neglect and critically related to both sub-acute and chronic deficits. Finally, there was a significant difference in the lesion volume between patients who recovered from neglect and patients with chronic deficits. The findings presented provide evidence that (i) the lesion location and lesion size can be used to successfully predict the outcome of neglect based on clinical CT scans, (ii) lesion location alone can serve as a critical predictor for persistent neglect symptoms, (iii) wide spread lesions are associated with neglect symptoms at the sub-acute stage but only some of these are critical for predicting whether neglect will become a chronic disorder and (iv) the severity of behavioural symptoms can be a useful predictor of recovery in the absence of neuroimaging findings on clinical scans. We discuss the implications for understanding the symptoms of the neglect syndrome, the recovery of function and the use of clinical scans to predict outcome
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