6,519 research outputs found

    Inclusive and semi-inclusive pion production in pp collisions at 102 and 400 GeV/c

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    We present a comparative study of inclusive and semi-inclusive pion production in pp collisions at 102 and 400 GeV/c. In particular, we examine the correlation between transverse and longitudinal momentum variables and the energy dependence of invariant cross sections.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/21788/1/0000183.pd

    Antiproton proton annihilations at 1.6-2.2 GeV/c into final states with a K1o meson

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    Antiproton proton annihilations into final states containing at least one K1o meson have been studied in a 150 000 picture bubble chamber experiment. The experiment covered six incident antiproton momenta in the range 1.6-2.2 GeV/c. Cross sections at each incident momentum are determined for the more abundantly produced final states, and momentum averaged cross sections are determined for some rarer final states, including . Copious resonance production, including double resonance production, is observed, and percentage contributions of different resonance channels are evaluated. Cross sections and resonance fractions are compared with results of other experiments at antiproton momenta in the range 0.7-3.7 GeV/c.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/34085/1/0000364.pd

    The A(Kstop−,π±Σ∓)A′A(K^-_{stop},\pi^\pm\Sigma^\mp)A' reaction on p-shell nuclei

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    This letter is concerned with the study of the Kstop−A→π±Σ∓A′K^-_{stop}A\rightarrow \pi^\pm\Sigma^\mp A' reaction in p-shell nuclei, i.e., 6,7Li^{6,7}Li, 9Be^9Be, 13C^{13}C and 16O^{16}O. The π±Σ∓/Kstop−\pi^\pm\Sigma^\mp / K^-_{stop} emission rates are reported as a function of AA. These rates are discussed in comparison with previous findings. The ratio π−Σ+/π+Σ−\pi^-\Sigma^+/\pi^+\Sigma^- in p-shell nuclei is found to depart largely from that on hydrogen, which provides support for large in-medium effects possibly generated by the sub-threshold Λ(1405)\Lambda(1405). The continuum momentum spectra of prompt pions and free sigmas are also discussed as well as the π±Σ∓\pi^\pm\Sigma^\mp missing mass behavior and the link with the reaction mechanism. The apparatus used for the investigation is the FINUDA spectrometer operating at the DAΦ\PhiNE ϕ\phi-factory (LNF-INFN, Italy).Comment: 14 pages, 5 figures, accepted for publication in Phys. Lett.

    Branching ratio change in K- absorption at rest and the nature of the Lambda(1405)

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    We investigate in-medium corrections to the branching ratio in K- absorption at rest and their effect on the (positively and negatively) charged pion spectrum. The in-medium corrections are due to Pauli blocking, which arises if the Lambda(1405) is assumed to be a Kˉ\bar{K}-nucleon bound state and leads to a density and momentum dependent mass shift of the Lambda(1405). Requiring that the optical potential as well as the branching ratio are derived from the same elementary T-matrix, we find that the in-medium corrected, density dependent T-matrix gives a better description of the K- absorption reaction than the free, density-independent one. This result suggests that the dominant component of the Lambda(1405) wave function is the KˉN\bar{K}N bound state.Comment: 8 Pages, Revtex with epsf, and embedded 8 ps figure

    Total Synthesis and Evaluation of c26-Hydroxyepothilone D Derivatives for Photoaffinity Labeling of β-Tubulin

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    Three photaffinity labeled derivatives of epothilone D were prepared by total synthesis, using efficient novel asymmetric synthesis methods for the preparation of two important synthetic building blocks. The key step for the asymmetric synthesis of (S,E)-3-(tert-butyldimethylsilyloxy)-4-methyl-5-(2-methylthiazol-4-yl)pent-4-enal involved a ketone reduction with (R)-Me-CBS-oxazaborolidine. For the synthesis of (5S)-5,7-di-[(tert-butyldimethylsilyl)oxy]-4,4-dimethylheptan-3-one an asymmetric Noyori reduction of a β-ketoester was employed. The C26 hydroxyepothilone D derivative was constructed following a well-established total synthesis strategy and the photoaffinity labels were attached to the C26 hydroxyl group. The photoaffinity analogues were tested in a tubulin assembly assay and for cytotoxicity against MCF-7 and HCT-116 cancer cell lines. The 3- and 4-azidobenzoic acid analogues were found to be as active as epothilone B in a tubulin assembly assay, but demonstrated significantly reduced cellular cytotoxicity compared to epothilone B. The benzophenone analogue was inactive in both assays. Docking and scoring studies were conducted that suggested that the azide analogues can bind to the epothilone binding site, but that the benzophenone analogue undergoes a sterically driven ligand rearrangement that interrupts all hydrogen bonding and therefore protein binding. Photoaffinity labeling studies with the 3-azidobenzoic acid derivative did not identify any covalently labeled peptide fragments, suggesting that the phenylazido side chain was predominantly solvent-exposed in the bound conformation

    Production properties of low-mass systems in pp collisions at 102 GeV/c

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    We examine in detail the properties of low-mass systems produced in the inclusive reaction p + p --> p + anything at 102 GeV/c. We find that the internal characteristics of these low-mass nucleon-multipion systems (the "anything"), at fixed values of mass (M), are similar to those found for produced hadrons in high-energy collisions at fixed incident hadron energies . The resemblance between the properties of the M2 system and the characteristics of [pi]p collisions at s = M2 is particularly striking.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22250/1/0000686.pd

    Laboratory angular distributions for the production of charged secondaries in inelastic proton-proton collisions at 102 GeV/c

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    Lab angular distributions for the production of charged secondary particles in inelastic proton-proton collisions are presented. Data are separately displayed for protons and for positive and negative mesons (pions and kaons combined).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22255/1/0000691.pd
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