50 research outputs found
Characterization of brush borders purified in iso-osmotic medium and microvillar membranes subfractionated from mouse small intestine
Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation
Background: Determinants of the clinical presentation of the leishmaniases are poorly understood but Leishmania species and strain differences are important. To examine the relationship between clinical presentation, species and isoenzyme polymorphisms, 56 Leishmania isolates from distinct presentations of American tegumentary leishmaniasis (ATL) from Ecuador were analyzed.
Methods: Isolates were characterized by multilocus enzyme electrophoresis for polymorphisms of 11 isoenzymes. Patients were infected in four different ecologic regions: highland and lowland jungle of the Pacific coast, Amazonian lowlands and Andean highlands.
Results: Six Leishmania species constituting 21 zymodemes were identified: L. (Viannia) panamensis (21 isolates,
7 zymodemes), L. (V.) guyanensis (7 isolates, 4 zymodemes), L. (V.) braziliensis (5 isolates, 3 zymodemes), L.
(Leishmania) mexicana (11 isolates, 4 zymodemes), L. (L.) amazonensis (10 isolates, 2 zymodemes) and L. (L.) major
(2 isolates, 1 zymodeme). L. panamensis was the species most frequently identified in the Pacific region and was
associated with several clinical variants of cutaneous disease (CL); eight cases of leishmaniasis recidiva cutis (LRC) found in the Pacific highlands were associated with 3 zymodemes of this species. Mucocutaneous leishmaniasis
found only in the Amazonian focus was associated with 3 zymodemes of L. braziliensis. The papular variant of CL,
Uta, found in the Andean highlands was related predominantly with a single zymodeme of L. mexicana.
Conclusion: Our data show a high degree of phenotypic variation within species, and some evidence for associations between specific variants of ATL (i.e. Uta and LRC) and specific Leishmania zymodemes. This study
further defines the geographic distribution of Leishmania species and clinical variants of ATL in Ecuador
Effects of Chronic Stress on Prefrontal Cortex Transcriptome in Mice Displaying Different Genetic Backgrounds
Stability analysis and suppression control of rotor oscillation for stepping motors by Lyapunov's direct method
Position control of ultrasonic motors using dead-zone compensation with fuzzy neural network
PESC Record - IEEE Annual Power Electronics Specialists Conference41871-1876PRIC
Investigation of influences of various losses on electromagnetic torque for surface-mounted permanent magnet synchronous motors
Speed Sensorless Control of Ultrasonic Motors Using Neural Network
10.1109/IECON.2003.1280003IECON Proceedings (Industrial Electronics Conference)1335-340IEPR