185 research outputs found
Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study
Differences in bioactivity between human insulin and insulin analogues approved for therapeutic use- compilation of reports from the past 20 years
In order to provide comprehensive information on the differences in bioactivity between human insulin and insulin analogues, published in vitro comparisons of human insulin and the rapid acting analogues insulin lispro (Humalog®), insulin aspart ( NovoRapid®), insulin glulisine (Apidra®), and the slow acting analogues insulin glargine (Lantus®), and insulin detemir (Levemir®) were gathered from the past 20 years (except for receptor binding studies). A total of 50 reports were retrieved, with great heterogeneity among study methodology. However, various differences in bioactivity compared to human insulin were obvious (e.g. differences in effects on metabolism, mitogenesis, apoptosis, intracellular signalling, thrombocyte function, protein degradation). Whether or not these differences have clinical bearings (and among which patient populations) remains to be determined
Effect of Ankaferd Blood Stopper on air leakage in the lung and prevention of bleeding: an experimental study
Identification of altered protein abundances in cholesteatoma matrix via mass spectrometry-based proteomic analysis
Inflammatory response and pneumocyte apoptosis during lung ischemia–reperfusion injury in an experimental pulmonary thromboembolism model
Beneficial effects of inhaled NO on apoptotic pneumocytes in pulmonary thromboembolism model
Entwicklung von Bildverabeitungsmethoden zur quantitativen Analyse des Gelenkknorpels in der Magnetresonanztomographie.
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