66 research outputs found
Comparative results of endoscopic and open methods of vein harvesting for coronary artery bypass grafting: a prospective randomized parallel-group trial
Understanding Gesture Expressivity through Muscle Sensing
Expressivity is a visceral capacity of the human body. To understand what makes a gesture expressive, we need to consider not only its spatial placement and orientation, but also its dynamics and the mechanisms enacting them. We start by defining gesture and gesture expressivity, and then present fundamental aspects of muscle activity and ways to capture information through electromyography (EMG) and mechanomyography (MMG). We present pilot studies that inspect the ability of users to control spatial and temporal variations of 2D shapes and that use muscle sensing to assess expressive information in gesture execution beyond space and time. This leads us to the design of a study that explores the notion of gesture power in terms of control and sensing. Results give insights to interaction designers to go beyond simplistic gestural interaction, towards the design of interactions that draw upon nuances of expressive gesture
A comprehensive review on learning curve associated problems in endoscopic vein harvesting and the requirement for a standardised training programme
Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth
Resident macrophages densely populate the normal arterial wall, yet their origins and the mechanisms that sustain them are poorly understood. Here we use gene-expression profiling to show that arterial macrophages constitute a distinct population among macrophages. Using multiple fate-mapping approaches, we show that arterial macrophages arise embryonically from CX3CR1+ precursors and postnatally from bone marrowâderived monocytes that colonize the tissue immediately after birth. In adulthood, proliferation (rather than monocyte recruitment) sustains arterial macrophages in the steady state and after severe depletion following sepsis. After infection, arterial macrophages return rapidly to functional homeostasis. Finally, survival of resident arterial macrophages depends on a CX3CR1-CX3CL1 axis within the vascular niche
Short-term outcomes of modified Y-graft technique in acute type a aortic dissection using the femoral artery bypass and one minute systemic circulatory arrest technique
Variations in Coronary Revascularization Practices and Their Effect on LongâTerm Outcomes
Background The degree of hospitalâlevel variation in the ratio of percutaneous coronary interventions to coronary artery bypass grafting procedures (PCI:CABG) and the association of the PCI:CABG ratio with clinical outcome are unknown. Methods and Results In a multicenter populationâbased study conducted in Ontario, Canada, we identified 44Â 288 patients from 19 institutions who had nonemergent diagnostic angiograms indicating severe multivessel coronary artery disease (2013â2017) and underwent a coronary revascularization procedure within 90Â days. Hospitals were divided into tertiles according to their adjusted PCI:CABG ratio into low (0.70â0.85, n=17Â 487), medium (1.01â1.17, n=15Â 275), and high (1.18â1.29, n=11Â 526) ratio institutions. Compared with low PCI:CABG ratio hospitals, hazard ratios (HRs) for major adverse cardiac and cerebrovascular events were higher at medium (HR, 1.19; 95% CI, 1.14â1.25) and high ratio (HR, 1.21; 95% CI, 1.15â1.27) hospitals during a median 3.3 (interquartile range 2.1â4.6) years followâup. When interventional cardiologists performed the diagnostic angiogram, the odds of the patient receiving PCI was higher (odds ratio, 1.37; 95% CI, 1.23â1.52) than when it was performed by noninterventional cardiologists, after accounting for patient characteristics. Having the diagnostic angiogram at an institution without cardiac surgical capabilities was independently associated with a higher risk of major adverse cardiac and cerebrovascular events (HR, 1.07; 95% CI, 1.02â1.11), death (HR, 1.09; 95% CI, 1.02â1.18), and myocardial infarction (HR, 1.10; 95% CI, 1.03â1.17). Conclusions Patients undergoing diagnostic angiography in hospitals with higher PCI:CABG ratio had higher rates of adverse outcomes, including major adverse cardiac and cerebrovascular events, myocardial infarction, and repeat revascularization. Presence of onâsite cardiac surgery was associated with better survival and lower major adverse cardiac and cerebrovascular events
Characterization of Type B Acute Aortic Dissection Patients With Presenting Spinal Cord Ischemia
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