4,393 research outputs found

    {DeepBlueR}: {L}arge-scale Epigenomic Analysis in {R}

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    Solid state television camera system Patent

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    Solid state television camera system consisting of monolithic semiconductor mosaic sensor and molecular digital readout system

    A cross-linguistic database of phonetic transcription systems

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    Contrary to what non-practitioners might expect, the systems of phonetic notation used by linguists are highly idiosyncratic. Not only do various linguistic subfields disagree on the specific symbols they use to denote the speech sounds of languages, but also in large databases of sound inventories considerable variation can be found. Inspired by recent efforts to link cross-linguistic data with help of reference catalogues (Glottolog, Concepticon) across different resources, we present initial efforts to link different phonetic notation systems to a catalogue of speech sounds. This is achieved with the help of a database accompanied by a software framework that uses a limited but easily extendable set of non-binary feature values to allow for quick and convenient registration of different transcription systems, while at the same time linking to additional datasets with restricted inventories. Linking different transcription systems enables us to conveniently translate between different phonetic transcription systems, while linking sounds to databases allows users quick access to various kinds of metadata, including feature values, statistics on phoneme inventories, and information on prosody and sound classes. In order to prove the feasibility of this enterprise, we supplement an initial version of our cross-linguistic database of phonetic transcription systems (CLTS), which currently registers five transcription systems and links to fifteen datasets, as well as a web application, which permits users to conveniently test the power of the automatic translation across transcription systems

    ILC Operating Scenarios

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    The ILC Technical Design Report documents the design for the construction of a linear collider which can be operated at energies up to 500 GeV. This report summarizes the outcome of a study of possible running scenarios, including a realistic estimate of the real time accumulation of integrated luminosity based on ramp-up and upgrade processes. The evolution of the physics outcomes is emphasized, including running initially at 500 GeV, then at 350 GeV and 250 GeV. The running scenarios have been chosen to optimize the Higgs precision measurements and top physics while searching for evidence for signals beyond the standard model, including dark matter. In addition to the certain precision physics on the Higgs and top that is the main focus of this study, there are scientific motivations that indicate the possibility for discoveries of new particles in the upcoming operations of the LHC or the early operation of the ILC. Follow-up studies of such discoveries could alter the plan for the centre-of-mass collision energy of the ILC and expand the scientific impact of the ILC physics program. It is envisioned that a decision on a possible energy upgrade would be taken near the end of the twenty year period considered in this report

    Influence of culture on pain comorbidity in women with and without temporomandibular disorder-pain

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    Evidence on cultural differences in prevalence and impact of common chronic pain conditions, comparing individuals with temporomandibular disorders (TMD) versus individuals without TMD, is limited. The aim was to assess cross-cultural comorbid pain conditions in women with chronic TMD pain. Consecutive women patients (n = 122) with the index condition of chronic TMD pain diagnosed per the research diagnostic criteria for TMD and TMD-free controls (n = 121) matched for age were recruited in Saudi Arabia, Italy and Sweden. Self-report questionnaires assessed back, chest, stomach and head pain for prevalence, pain intensity and interference with daily activities. Logistic regression was used for binary variables, and ancova was used for parametric data analysis, adjusting for age and education. Back pain was the only comorbid condition with a different prevalence across cultures; Swedes reported a lower prevalence compared to Saudis (P 50% due to back pain compared to Italians or Swedes (P < 0·01). Headache was the most common comorbid condition in all three cultures. The total number of comorbid conditions did not differ cross-culturally but were reported more by TMD-pain cases than TMD-free controls (P < 0·01). For both back and head pain, higher average pain intensities (P < 0·01) and interference with daily activities (P < 0·01) were reported by TMD-pain cases, compared to TMD-free controls. Among TMD-pain cases, Italians reported the highest pain-related disability (P < 0·01). Culture influences the associated comorbidity of common pain conditions. The cultural influence on pain expression is reflected in different patterns of physical representation

    NLO-QCD corrections to e+ e- --> hadrons in models of TeV-scale gravity

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    We present results on NLO-QCD corrections to the process e+ e- --> hadrons via photon-, Z- and graviton-exchange in the context of TeV-scale gravity models. The quantitative impact of these QCD corrections for searches of extra dimensions at a Linear Collider is briefly discussed.Comment: 10 pages, LaTeX, using axodraw.st

    The effect of culture on pain sensitivity

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    Cross-cultural differences in pain sensitivity have been identified in pain-free subjects as well as in chronic pain patients. The aim was to assess the impact of culture on psychophysical measures using mechanical and electrical stimuli in patients with temporomandibular disorder (TMD) pain and pain-free matched controls in three cultures. This case-control study compared 122 female cases of chronic TMD pain (39 Saudis, 41 Swedes and 42 Italians) with equal numbers of age- and gender-matched TMD-free controls. Pressure pain threshold (PPT) and tolerance (PPTo) were measured over one hand and two masticatory muscles. Electrical perception threshold and electrical pain threshold (EPT) and tolerance (EPTo) were recorded between the thumb and index fingers. Italian females reported significantly lower PPT in the masseter muscle than other cultures (P < 0.001) and in the temporalis muscle than Saudis (P = 0.003). Swedes reported significantly higher PPT in the thenar muscle than other cultures (P = 0.017). Italians reported significantly lower PPTo in all muscles than Swedes (P ≤ 0.006) and in the masseter muscle than Saudis (P < 0.001). Italians reported significantly lower EPTo than other cultures (P = 0.01). Temporomandibular disorder cases, compared to TMD-free controls, reported lower PPT and PPTo in all the three muscles (P < 0.001). This study found cultural differences between groups in the PPT, PPTo and EPTo. Overall, Italian females reported the highest sensitivity to both mechanical and electrical stimulation, while Swedes reported the lowest sensitivity. Mechanical pain thresholds differed more across cultures than did electrical pain thresholds. Cultural factors may influence response to type of pain test

    Ricci Solitons and Einstein-Scalar Field Theory

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    B List has recently studied a geometric flow whose fixed points correspond to static Ricci flat spacetimes. It is now known that this flow is in fact Ricci flow modulo pullback by a certain diffeomorphism. We use this observation to associate to each static Ricci flat spacetime a local Ricci soliton in one higher dimension. As well, solutions of Euclidean-signature Einstein gravity coupled to a free massless scalar field with nonzero cosmological constant are associated to shrinking or expanding Ricci solitons. We exhibit examples, including an explicit family of complete expanding solitons which can be thought of as a Ricci flow for a complete Lorentzian metric. The possible generalization to Ricci-flat stationary metrics leads us to consider an alternative to Ricci flow.Comment: 17 pages, 1 figure; Revised version (organizational changes, other minor revisions and corrections, citations corrected and added), to appear in CQ

    Large and Almost Maximal Neutrino Mixing within the Type II See-Saw Mechanism

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    Within the type II see-saw mechanism the light neutrino mass matrix is given by a sum of a direct (or triplet) mass term and the conventional (type I) see-saw term. Both versions of the see-saw mechanism explain naturally small neutrino masses, but the type II scenario offers interesting additional possibilities to explain large or almost maximal or vanishing mixings which are discussed in this paper. We first introduce ``type II enhancement'' of neutrino mixing, where moderate cancellations between the two terms can lead to large neutrino mixing even if all individual mass matrices and terms generate small mixing. However, nearly maximal or vanishing mixings are not naturally explained in this way, unless there is a certain initial structure (symmetry) which enforces certain elements of the matrices to be identical or related in a special way. We therefore assume that the leading structure of the neutrino mass matrix is the triplet term and corresponds to zero U_{e3} and maximal theta_{23}. Small but necessary corrections are generated by the conventional see-saw term. Then we assume that one of the two terms corresponds to an extreme mixing scenario, such as bimaximal or tri-bimaximal mixing. Deviations from this scheme are introduced by the second term. One can mimic Quark-Lepton Complementarity in this way. Finally, we note that the neutrino mass matrix for tri-bimaximal mixing can be -- depending on the mass hierarchy -- written as a sum of two terms with simple structure. Their origin could be the two terms of type II see-saw.Comment: 25 pages. Comments and references added, to appear in JHE
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