Lung surfactant in subacute pulmonary disease

Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung or in the acutely inflamed mature lung are well described. However, in a variety of subacute diseases of the mature lung, abnormalities of lung surfactant may also be of importance. These diseases include chronic obstructive pulmonary disease, asthma, cystic fibrosis, interstitial lung disease, pneumonia, and alveolar proteinosis. Understanding of the mechanisms that disturb the lung surfactant system may lead to novel rational therapies for these diseases

DESIGN OF THE FLAT-TOP ACCELERATION SYSTEM FOR THE JAERI AVF CYCLOTRON

Abstract A flat-top acceleration system for the JAERI AVF cyclotron has been designed. The fifth harmonic of the fundamental frequency is used to obtain uniform energy gain. To determine optimum parameters of the flat-top system, a cold model test was carried out and flat-top waveforms of the voltages were observed successfully in the whole range of the fundamental frequency. An rf power required for generating a flat-top dee voltage of 30 kV was estimated to be about 1 kW. The design of the flat-top cavity is being modified using the MAFIA code

Piezo1-pannexin-1-P2X3 axis in odontoblasts and neurons mediates sensory transduction in dentinal sensitivity

©2022 Ohyama, Ouchi, Kimura, Kurashima, Yasumatsu, Nishida, Hitomi, Ubaidus, Kuroda, Ito, Takano, Ono, Mizoguchi, Katakura and Shibukawa. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms