Optimization of air curtain performance by particle image velocimetry measurements and computational fluid dynamics simulations:turbulence model validation

Air curtains can be applied to aerodynamically separate two environments. Air curtains are plane impinging jets at high-Reynolds numbers, preventing the transfer of heat and mass from one environment to another. The performance of an air curtain is called the separation efficiency, which depends on a wide range of jet and environmental parameters, such as jet velocity and turbulence intensity, jet thickness, air temperature differences and pressure differences over the air curtain. This study presents the first results of ongoing research on the optimization of air curtain performance. The first results consist of reduced-scale experiments in a water channel using Particle Image Velocimetry (PIV), and of steady Reynolds-averaged Navier-Stokes Computational Fluid Dynamics (CFD) simulations. The PIV measurements are used to validate the CFD model. Comparison of the experimental results with the results obtained with steady RANS CFD simulations in combination with three different turbulence models showed a fairly accurate agreement

Gambling taxation in today’s Russia : principles, practices and actual figures

The article is devoted to today's situation and prospects for the development of gambling taxation in the country. The gambling industry is continually developed. Currently, this type of entrepreneurial activities can be found almost throughout the Russian Federation. But the problem of gambling industry is associated, to a large extent, with the fact that it is rather difficult to control the income and expense of bookmakers, owners of casinos and slot machines. Insufficient transparency of gambling industry leads to new restrictions or prohibitions by the state, instead of implementing an effective taxation system. As the objects for the study, the authors selected the main elements of the tax on gambling. In this article the dynamics of the number of taxpayers, subjects of taxation and amount of budget income by taxing the gambling industry over time is analysed. As a result of the study the problems of gambling taxation are defined and their possible solutions are proposed.peer-reviewe

DEVELOPMENT OF ALGORITHM FOR CREATING ATOM-ATOMIC MAPPING USING "NAIVE" BAYES MACHINE LEARNING METHOD

52-5

СТАТЬЯ ОТОЗВАНА: Инновационные технологии для решения экологических проблем в мировом сообществе

Retracted articlePurpose: the purpose of the article is the disclosure of environmental problems and prospects commercialization of intellectual property within development of innovative information technologies in the conditions of integration of economies into the world economy, identification of opportunities of forming, organization, financing, management, ownership, commercialization and protection of innovative technologies and intellectual property. Relevance of the chosen subject is caused by the current state of ecology and problems of commercialization of intellectual property in development of innovative information technologies within the conditions of integration of economies into the world economy. The existing changes of the current legislation and tendencies of development of the industry of innovative information technologies in field of ecology in the Russian Federation require cardinal review because of its low competitiveness. Ensuring sustainable development of the country directly depends on implementation of innovative information technologies, not only within the sphere of ecology, but also in all industries of the national economy of Russia. Especially important direction of development of innovations is the field of information technologies with its further implementation in innovative productions and provision of services with a focus on protection of ecology and healthcare. Methods: the methodology of the solution of objectives is based on usage of a method of dialectic research, methods of the economic analysis, forecasting, the situational and systemic analysis, expert evaluations and the analysis of empirical data. Results: in the process of researching the direction of solving environmental problems, the author studied foreign and Russian programs based on innovative technologies in this field and identified current proposals regarding the practical implementation of partnerships in the form of Public Private Partnerships PPPs. Conclusions and Relevance: the practical importance of the work consists in identification of intellectual property in the area of development of innovative technologies, forecasting of their economic activity, the choice of optimal models of financing for ensuring sustainable development of the country and competitiveness of the Russian innovative technologies on the world market. Статья отозванаЦель: Целью статьи является раскрытие экологических проблем и перспектив коммерциализация интеллектуальной собственности в развитии инновационных информационных технологий в условиях интеграции экономик в мировое хозяйство, выявление возможностей формирования, организации, финансирования, управления, владения, коммерциализации и защиты инновационных технологий и интеллектуальной собственности. Актуальность выбранной темы обусловлена современным состоянием экологии и проблемами коммерциализация интеллектуальной собственности в развитии инновационных информационных технологий в условиях интеграции экономик в мировое хозяйство. Существующие изменения действующего законодательства и тенденции развития отрасли инновационных информационных технологий в части экологии в Российской Федерации требуют кардинального пересмотра из-за низкой конкурентоспособности его. Обеспечение устойчивого развития страны напрямую зависит от внедрения инновационных информационных технологий не только в сферу экологии, но и во все отрасли народного хозяйства России. Особенно важным направлением развития инноваций является отрасль информационных технологий с дальнейшим внедрением их в инновационные производства и оказание услуг в рамках защиты экологии и здравоохранения. Методология проведения работы: Методология решения поставленных задач основывается на использовании метода диалектического исследования, методов экономического анализа, прогнозирования, ситуационного и системного анализа, экспертных оценок и анализа эмпирических данных. Результаты работы: В процессе исследования показаны направления решения экологических проблем, изучены зарубежные и российские программы в данной сфере, базирующиеся на инновационных технологиях, и выявлены актуальные предложения, касающиеся практической реализации партнерства в форме ГЧП. Выводы: Практическая значимость работы заключается в выявлении интеллектуальной собственности в части развития инновационных технологий, прогнозировании их хозяйственной деятельности, выбора оптимальных моделей финансирования для обеспечения устойчивого развития страны и конкурентоспособности на мировом рынке российских инновационных технологий.

CGR-DB. INTERACTIVE REACTION DATABASE AND CGR-BASED SEARCH ENGINE.

6

Evidence for a Role for Interleukin-17, Th17 Cells and Iron Homeostasis in Protective Immunity against Tuberculosis in Cynomolgus Macaques.

Tuberculosis (TB) remains a major global public health problem. The only vaccine, BCG, gives variable protection, especially in adults, so several new vaccines are in clinical trials. There are no correlates of protective immunity to TB; therefore vaccines progress through lengthy and expensive pre-clinical assessments and human trials. Correlates of protection could act as early end-points during clinical trials, accelerating vaccine development and reducing costs. A genome-wide microarray was utilised to identify potential correlates of protection and biomarkers of disease induced post-BCG vaccination and post-Mycobacterium tuberculosis challenge in PPD-stimulated peripheral blood mononuclear cells from cynomolgus macaques where the outcome of infection was known. Gene expression post BCG-vaccination and post challenge was compared with gene expression when the animals were naïve. Differentially expressed genes were identified using a moderated T test with Benjamini Hochberg multiple testing correction. After BCG vaccination and six weeks post-M. tuberculosis challenge, up-regulation of genes related to a Th1 and Th17 response was observed in disease controllers. At post-mortem, RT-PCR revealed an up-regulation of iron regulatory genes in animals that developed TB and down-regulation of these genes in disease controllers, indicating the ability to successfully withhold iron may be important in the control of TB disease. The induction of a balanced Th1 and Th17 response, together with expression of effector cytokines, such as IFNG, IL2, IL17, IL21 and IL22, could be used as correlates of a protective host response

DEVELOPMENT OF ALGORITHM FOR CREATING ATOM-ATOMIC MAPPING USING "NAIVE" BAYES MACHINE LEARNING METHOD

52-5

Prevalence of Ureaplasma spp. and Mycoplasma hominis in healthy women and patients with flora alterations

The objective was to estimate the prevalence of Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum in healthy women and patients with altered vaginal microflora. Vaginal samples from 2594 unselected female patients were divided into normal, bacterial vaginosis (BV), and aerobic vaginitis (AV) groups and tested for U. parvum, U. urealyticum and M. hominis. Normal flora was detected in 1773 patients (68.4%), BV in 754 patients (29.1%), and AV in 67 patients (2.6%). In the control group, 771 (43.5%) patients were U. parvum positive, 104 (5.9%) were U. urealyticum positive, and 158 (8.9%) were M. hominis positive. In the BV group, those bacteria were detected in 452 (59.9%), 102 (13.5%), and 202 (26.8%) patients, respectively (P < 0.001); in the AV group, those were detected in 16 (23.9%), 3 (4.5%), and 4 (6.0%) patients, respectively (P < 0.001; 0.63 and 0.40, respectively). This study demonstrated that mycoplasmas may be a marker or a symbiont of the BV flora but not AV flora. © 201

Optimization of air-curtain sealing efficiency with respect to heat transfer in naturally ventilated buildings

This study presents results of coupled 3D steady Reynolds-averaged Navier-Stokes (RANS) Computational Fluid Dynamics (CFD) simulations of an isolated naturally-ventilated building with the application of an air curtain to prevent heat transfer across a doorway. The considered parameters include air curtain velocity, width and angle, indoor and outdoor tempera-tures, and wind flow. The results showed that higher temperatures inside the studied building were provided for: (1) higher jet velocities Vac for a jet angle a = 15deg, when jet width wjet is constant; (2) larger jet width wjet, when jet angle a and jet momentum Mac' are constant; (3) jet angle a = 0deg, when jet velocity Vac and jet width wjet are constant. The results also showed that for an air curtain with a = 0deg the air jet slightly bended to the outside that is possibly caused by stagnation-zone flow in front of the building

Optimization of air curtain performance by particle image velocimetry measurements and computational fluid dynamics simulations: turbulence model validation

Air curtains can be applied to aerodynamically separate two environments. Air curtains are plane impinging jets at high-Reynolds numbers, preventing the transfer of heat and mass from one environment to another. The performance of an air curtain is called the separation efficiency, which depends on a wide range of jet and environmental parameters, such as jet velocity and turbulence intensity, jet thickness, air temperature differences and pressure differences over the air curtain. This study presents the first results of ongoing research on the optimization of air curtain performance. The first results consist of reduced-scale experiments in a water channel using Particle Image Velocimetry (PIV), and of steady Reynolds-averaged Navier-Stokes Computational Fluid Dynamics (CFD) simulations. The PIV measurements are used to validate the CFD model. Comparison of the experimental results with the results obtained with steady RANS CFD simulations in combination with three different turbulence models showed a fairly accurate agreement