3 research outputs found
Water Soluble Cyclophosphamide Adducts of Rhodium(II) Keto-Gluconate and Glucuronate. Synthesis, Characterization and In Vitro Cytostatic Assays
The synthesis, characterization and biological assays of two new rhodium carboxylate sugar derivatives and
respective cyclosphosphamide adducts are described. The compounds, characterized by 13C
and 1H NMR,
infrared and UV-visible spectra, presented high water solubility and hydration grades were confirmed given the
concordance between thermal and CHN analyses. The adducts were active in vitro against K-562 cells