Profile, predispositions and preferences of the UNIGS e-students

W początkowej fazie swojego rozwoju edukacja w zakresie GIS sprowadzała się głównie do wykształcenia specjalistów dysponujących wiedza techniczna. Obecnie, masowe wkroczenie GIS w sferę usług wymaga również znajomości zagadnień biznesu. W pracy podjęto próbę odpowiedzi na pytania o to, czy oferta kształcenia w zakresie GIS nadąża za głównym trendem rozwoju technologii oraz jak z tej oferty korzystają studenci. Dokonano analizy profilu, predyspozycji i preferencji studentów Studiów Podyplomowych Systemy Informacji Geograficznej UNIGIS, prowadzonych na Uniwersytecie Jagiellońskim, w kontekście możliwości, jakie te studia oferują. Badania oparto na informacjach zgromadzonych w czasie rekrutacji oraz na wynikach ankiet przeprowadzonych wśród studentów. Studia UNIGIS kształtują umiejętności dostrzegania możliwości zastosowania GIS i kierowania zespołem ludzi posiadających wiedze techniczna w tym zakresie. Studenci UNIGIS nabywają również umiejętności nauki, pracy i współpracy online oraz radzenia sobie z dużą ilością informacji. Dodatkowo za sprawa przynależności do globalnej społeczności w ramach sieci UNIGIS International Association mają możliwość nawiązywania kontaktów profesjonalnych w Polsce i zagranicą. Niemniej jednak, wyniki przeprowadzonej analizy dowodzą, że mimo obecności nowych tendencji rozwoju technologii GIS w ofercie studiów UNIGIS, nie znajdują sie one jeszcze w centrum zainteresowania osób podejmujących te studia.In its preliminary development phase, GIS education has focused mainly on delivering specialists furnished with technical knowledge. Currently, widespread presence of GIS in the field of www services requires them to be familiar with the business-related issues. This study attempts to give the answer to some questions. Does the GIS educational offer keep pace with the main technology development trend and how do students make use of this offer? The analysis of the profile, predispositions and preferences of the students attending the Postgraduate Studies in Geographic Information Systems UNIGIS at the Jagiellonian University was carried out in comparison with the study prospects. The research was based on the information retrieved during the enrolment and on the results of survey given out to students. In its preliminary development phase, GIS education has focused mainly on delivering specialists furnished with technical knowledge. Currently, widespread presence of GIS in the field of www services requires them to be familiar with the business-related issues. This study attempts to give the answer to some questions. Does the GIS educational offer keep pace with the main technology development trend and how do students make use of this offer? The analysis of the profile, predispositions and preferences of the students attending the Postgraduate Studies in Geographic Information Systems UNIGIS at the Jagiellonian University was carried out in comparison with the study prospects. The research was based on the information retrieved during the enrolment and on the results of survey given out to students

Rapeseed biofuel. Preparation of raw material for biodiesel production in agricultural household conditions. Pilot methanolysis processes

Scharakteryzowano olej rzepakowy jako surowiec do produkcji biodiesla i opisano etapy procesu transestryfikacji. Oceniono metody wydobywania oleju rzepakowego poprzez tłoczenie w warunkach gospodarstwa rolnego i scharakteryzowano oleje pod względem przydatności do reakcji metanolizy (zawartość fosforu, LK, LOO, skład kwasów tłuszczowych). Przeprowadzono wstępne laboratoryjne reakcje transestryfikacji i na ich podstawie wytypowano parametry reakcji w skali ćwierćtechnicznej. Stopień konwersji oleju do estrów metylowych kwasów tłuszczowych (EMKT) oznaczano poprzez pomiar współczynnika załamania światła.Rapeseed oil has been characterized as a raw material in biodiesel production and stages of this process have been described. An evaluation of methods of extracting oil from rapeseed has been performed. The oil has been evaluated on its usefulness for methanolysis process (phosphorus content, fatty acid composition, acid and peroxide values). Preliminary transesterification reactions have been conducted on a laboratory scale and, based on the obtained results, parameters for household scale process have been chosen. The stage of oil-into-FAME conversion has been determined through refractive index measurement

Electronic Cigarettes and Head and Neck Cancer Risk-Current State of Art

Simple Summary The risk of developing cancer is always higher for tobacco smokers than for non-smokers. Electronic cigarettes (e-cigarettes) have become increasingly popular in the last decade and are considered less harmful than traditional tobacco products, due to the lower content of toxic and carcinogenic compounds. However, this is still a controversial issue. This paper contains a review of previous reports on the composition of e-cigarettes and their impact on the pathogenesis and risk of head and neck cancer (HNC). The authors reviewed articles on both toxic and carcinogenic compounds contained in e-cigarettes and their molecular and health effects on the upper respiratory tract in comparison to traditional tobacco cigarettes. In conclusion, the studies discussed in the review strongly suggest that more long-term studies are needed to better address the safety of e-cigarettes. E-cigarettes have become increasingly popular in the last decade and are considered less harmful than traditional tobacco products due to the lower content of toxic and carcinogenic compounds. However, this is still a controversial issue. This paper contains a review of previous reports on the composition of e-cigarettes and their impact on the pathogenesis and risk of head and neck cancer (HNC). The objective of the review was to compare the molecular and health effects of e-cigarette use in relation to the effects of traditional cigarette smoking in the upper respiratory tract, and to assess the safety and effect of e-cigarettes on HNC risk. A review for English language articles published until 31 August 2020 was made, using a PubMed (including MEDLINE), CINAHL Plus, Embase, Cochrane Library and Web of Science data. The authors reviewed articles on both toxic and carcinogenic compounds contained in e-cigarettes and their molecular and health effects on the upper respiratory tract in comparison to tobacco cigarettes. The risk of developing head and neck squamous cell carcinoma (HNSCC) remains lower in users of e-cigarettes compared with tobacco smokers. However, more long-term studies are needed to better address the safety of e-cigarettes.Peer reviewe

Electronic Cigarettes and Head and Neck Cancer Risk—Current State of Art

E-cigarettes have become increasingly popular in the last decade and are considered less harmful than traditional tobacco products due to the lower content of toxic and carcinogenic compounds. However, this is still a controversial issue. This paper contains a review of previous reports on the composition of e-cigarettes and their impact on the pathogenesis and risk of head and neck cancer (HNC). The objective of the review was to compare the molecular and health effects of e-cigarette use in relation to the effects of traditional cigarette smoking in the upper respiratory tract, and to assess the safety and effect of e-cigarettes on HNC risk. A review for English language articles published until 31 August 2020 was made, using a PubMed (including MEDLINE), CINAHL Plus, Embase, Cochrane Library and Web of Science data. The authors reviewed articles on both toxic and carcinogenic compounds contained in e-cigarettes and their molecular and health effects on the upper respiratory tract in comparison to tobacco cigarettes. The risk of developing head and neck squamous cell carcinoma (HNSCC) remains lower in users of e-cigarettes compared with tobacco smokers. However, more long-term studies are needed to better address the safety of e-cigarettes

Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 Å Crystal Structure of the N‑Terminal Domain of RSK2 with Bound Inhibitor

The p90 ribosomal S6 family of kinases (RSK) are potential drug targets, due to their involvement in cancer and other pathologies. There are currently only two known selective inhibitors of RSK, but the basis for selectivity is not known. One of these inhibitors is a naturally occurring kaempferol-α-l-diacetylrhamnoside, SL0101. Here, we report the crystal structure of the complex of the N-terminal kinase domain of the RSK2 isoform with SL0101 at 1.5 Å resolution. The refined atomic model reveals unprecedented structural reorganization of the protein moiety, as compared to the nucleotide-bound form. The entire N-lobe, the hinge region, and the αD-helix undergo dramatic conformational changes resulting in a rearrangement of the nucleotide binding site with concomitant formation of a highly hydrophobic pocket spatially suited to accommodate SL0101. These unexpected results will be invaluable in further optimization of the SL0101 scaffold as a promising lead for a novel class of kinase inhibitors

Biotechnological aspects of cold-active enzymes

Cold-adapted enzymes produced by organisms inhabiting permanently low temperature environments are typically characterized by a high activity at low to moderate temperatures and a poor thermal stability. Such characteristics make these enzymes highly attractive for various applications where they can enable more efficient, cost-effective, and environmentally friendlier processes than higher temperature-adapted enzymes. In this chapter, the biotechnological aspects of coldadapted enzymes and their application in industry are reviewed and discussed with a focus on cleaning/detergents, food and beverages, molecular biology, biomedicine, pharmaceuticals, cosmetics, textiles, biofuels, and materials applications.s T.C. is supported by the Fundac¸~ao para a Cieˆncia e a Tecnologia (FCT), the European Social Fund, the Programa Operacional Potencial Humano and the Investigador FCT Programme (IF/01635/2014). M.B. acknowledges the FCT for grant PD/BD/113810/2015 within the Doctoral Program in Applied and Environmental Microbiology. This work was funded by the European Regional Development Fund (ERDF) through project EcoAgriFood (NORTE-01-0145- FEDER-000009) via the North Portugal Regional Operational Programme (NORTE 2020) under the PORTUGAL 2020 Partnership Agreement. The FCT is thanked for their funding through EngXyl (EXPL/BBB-BIO/1772/2013-FCOMP-01-0124-FEDER-041595) and the strategic program UID/BIA/04050/2013 (POCI-01-0145-FEDER-007569). All the technical staff at the CBMA are thanked for their skillful technical assistance.info:eu-repo/semantics/publishedVersio