6 research outputs found

    BazHum : baza zawartości czasopism humanistycznych. Dokonania i perspektywy

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    The goal of the project Bazhum is to create a database of contents of Polish humanities journals. We plan to upload the list of contents from a wide spectrum of journals. We are currently researching the titles. In the field of our interest are all journals since the mid-19th century, they are being worked on from the first issue. It is already possible to do a basic search of the database by the names of authors and titles of articles. We are currently developing the search options to make it possible to do an advanced search by keywords, fragments of abstracts, Bolean operators etc. The project team has a modular structure: service, librarians and cataloguers. For many months we have been working with external institutions, like the libraries of Polish Academy of Science (PAN) and others. We receive a lot of positive feedback from the world of academia, regarding the usefulness of the database Bazhum. It starts even to be used by libraries in creating bibliographies of individual authors and in creating the indexes of contents for journals over a span of many years. We have developed a group of tools for editing and data collection. We have adopted the standards of bibliographic description in modern bibliographic databases. A collection of approx. 50.000 simplifed bibliographic records is accessible on the YADDA platform

    BazHum : baza zawartości czasopism humanistycznych. Dokonania i perspektywy

    Get PDF
    The goal of the project Bazhum is to create a database of contents of Polish humanities journals. We plan to upload the list of contents from a wide spectrum of journals. We are currently researching the titles. In the field of our interest are all journals since the mid-19th century, they are being worked on from the first issue. It is already possible to do a basic search of the database by the names of authors and titles of articles. We are currently developing the search options to make it possible to do an advanced search by keywords, fragments of abstracts, Bolean operators etc. The project team has a modular structure: service, librarians and cataloguers. For many months we have been working with external institutions, like the libraries of Polish Academy of Science (PAN) and others. We receive a lot of positive feedback from the world of academia, regarding the usefulness of the database Bazhum. It starts even to be used by libraries in creating bibliographies of individual authors and in creating the indexes of contents for journals over a span of many years. We have developed a group of tools for editing and data collection. We have adopted the standards of bibliographic description in modern bibliographic databases. A collection of approx. 50.000 simplifed bibliographic records is accessible on the YADDA platform

    Relationship Between Anti-DFS70 Autoantibodies and Oxidative Stress

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    Background: The anti-DFS70 autoantibodies are one of the most commonly and widely described agent of unknown clinical significance, frequently detected in healthy individuals. It is not known whether the DFS70 autoantibodies are protective or pathogenic. One of the factors suspected of inducing the formation of anti-DFS70 antibodies is increased oxidative stress. We evaluated the coexistence of anti-DFS70 antibodies with selected markers of oxidative stress and investigated whether these antibodies could be considered as indirect markers of oxidative stress. Methods: The intensity of oxidative stress was measured in all samples via indices of free-radical damage to lipids and proteins such as total oxidant status (TOS), concentrations of lipid hydroperoxides (LPH), lipofuscin (LPS), and malondialdehyde (MDA). The parameters of the non-enzymatic antioxidant system, such as total antioxidant status (TAS) and uric acid concentration (UA), were also measured, as well as the activity of superoxide dismutase (SOD). Based on TOS and TAS values, the oxidative stress index (OSI) was calculated. All samples were also tested with indirect immunofluorescence assay (IFA) and 357 samples were selected for direct monospecific anti DFS70 enzyme-linked immunosorbent assay (ELISA) testing. Results:: The anti-DFS70 antibodies were confirmed by ELISA test in 21.29% of samples. Compared with anti-DFS70 negative samples we observed 23% lower concentration of LPH (P = .038) and 11% lower concentration of UA (P = .005). TOS was 20% lower (P = .014). The activity of SOD was up to 5% higher (P = .037). The Pearson correlation showed weak negative correlation for LPH, UA, and TOS and a weak positive correlation for SOD activity. Conclusion: In samples positive for the anti-DFS70 antibody a decreased level of oxidative stress was observed, especially in the case of samples with a high antibody titer. Anti-DFS70 antibodies can be considered as an indirect marker of reduced oxidative stress or a marker indicating the recent intensification of antioxidant processes
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