North-South Distribution of Solar Flares during Cycle 23

In this paper, we investigate the spatial distribution of solar flares in the northern and southern hemisphere of the Sun that occurred during the period 1996 to 2003. This period of investigation includes the ascending phase, the maximum and part of descending phase of solar cycle 23. It is revealed that the flare activity during this cycle is low compared to previous solar cycle, indicating the violation of Gnevyshev-Ohl rule. The distribution of flares with respect to heliographic latitudes shows a significant asymmetry between northern and southern hemisphere which is maximum during the minimum phase of the solar cycle. The present study indicates that the activity dominates the northern hemisphere in general during the rising phase of the cycle (1997-2000). The dominance of northern hemisphere is shifted towards the southern hemisphere after the solar maximum in 2000 and remained there in the successive years. Although the annual variations in the asymmetry time series during cycle 23 are quite different from cycle 22, they are comparable to cycle 21.Comment: 6 pages, 2 figures, 1 table; Accepted for the publication in the proceedings of international solar workshop held at ARIES, Nainital, India on "Transient Phenomena on the Sun and Interplanetary Medium" in a special issue of "Journal of Astrophysics and Astronomy (JAA)

DEVELOPMENT OF A FAST MICRON-RESOLUTION BEAM POSITION MONITOR SIGNAL PROCESSOR FOR LINEAR COLLIDER BEAMBASED FEEDBACK SYSTEMS

We present the design of a prototype fast beam position monitor (BPM) signal processor for use in inter-bunch beam-based feedbacks for linear colliders and electron linacs. We describe the FONT4 intra-train beam-based digital position feedback system prototype deployed at the Accelerator test facility (ATF) extraction line at KEK, Japan. The system incorporates a fast analogue beam position monitor front-end signal processor, a digital feedback board, and a fast kicker-driver amplifier. The total feedback system latency is less than 150ns, of which less than 10ns is used for the BPM processor. We report preliminary results of beam tests using electron bunches separated by c. 150ns. Position resolution of order 1 micron was obtained

BEAM TEST RESULTS WITH THE FONT4 ILC PROTOTYPE INTRA-TRAIN BEAM FEEDBACK SYSTEM

We present the design and beam test results of a prototype beam-based digital feedback system for the Interaction Point of the International Linear Collider. A custom analogue front-end processor, FPGA-based digital signal processing board, and kicker drive amplifier have been designed, built, and tested on the extraction line of the KEK Accelerator Test Facility (ATF). The system was measured to have a latency of approximately 140 ns

Latest Beam Test Results of the FONT4 ILC Intra-train Feedback System Prototype

We present the design and preliminary results of a prototype beam-based digital feedback system for the Interaction Point of the International Linear Collider. A custom analogue front-end processor, FPGA-based digital signal processing board, and kicker drive amplifier have been designed, built, and tested on the extraction line of the KEK Accelerator Test Facility (ATF). The system was measured to have a latency of approximately 140 ns.Comment: 4 pages, 6 figures, Proceedings of LCWS/ILC0

How Do Young Adults Prefer to Access Mental Health Information?

KT strategies for sharing mental health information need to include both active and passive options for young adults. This includes the use of both old and new media tools.York’s Knowledge Mobilization Unit provides services and funding for faculty, graduate students, and community organizations seeking to maximize the impact of academic research and expertise on public policy, social programming, and professional practice. It is supported by SSHRC and CIHR grants, and by the Office of the Vice-President Research & Innovation. [email protected] www.researchimpact.c

Pressure reversal study through tensile tests

This paper is a summary of the results from a study of the variables related to pressure reversal and was sponsored by the US Department of Transportation, Office of Pipeline Safety. The circumferential pipe stress, which is the most significant variable in pressure reversal, was examined by using tensile specimens and then relating the results to pressurized pipe. A model is proposed that gives some insight into how pressure reversal can be minimized when a section of pipe is being hydrotested. Twenty tensile specimens from X-42 electric resistance welded (ERW) pipe and twenty specimens from X-52 ERW pipe were tested. Each specimen had a machined flaw. The flaw regions were monitored using strain gages and photoelasticity. These tensile tests represent the first phase of a research effort to examine and understand the variables related to pressure reversal. The second phase of this effort will be with pipe specimens and presently is in progress

Evolution of central pattern generators for the control of a five-link bipedal walking mechanism

Central pattern generators (CPGs), with a basis is neurophysiological studies, are a type of neural network for the generation of rhythmic motion. While CPGs are being increasingly used in robot control, most applications are hand-tuned for a specific task and it is acknowledged in the field that generic methods and design principles for creating individual networks for a given task are lacking. This study presents an approach where the connectivity and oscillatory parameters of a CPG network are determined by an evolutionary algorithm with fitness evaluations in a realistic simulation with accurate physics. We apply this technique to a five-link planar walking mechanism to demonstrate its feasibility and performance. In addition, to see whether results from simulation can be acceptably transferred to real robot hardware, the best evolved CPG network is also tested on a real mechanism. Our results also confirm that the biologically inspired CPG model is well suited for legged locomotion, since a diverse manifestation of networks have been observed to succeed in fitness simulations during evolution.Comment: 11 pages, 9 figures; substantial revision of content, organization, and quantitative result

Frailty and treatment outcome in advanced gastro-oesophageal cancer: An exploratory analysis of the GO2 trial

Introduction Research into the optimal management of frail patients with cancer is limited and treatment decision-making in this cohort can be difficult. A number of measures have been developed to assess frailty, but few studies explore the correlation between frailty measures and cancer treatment outcomes. Methods This retrospective cohort study is an exploratory analysis of the GO2 randomised controlled trial. GO2 recruited both older and frail younger patients commencing first-line palliative chemotherapy for advanced gastro-oesophageal (aGO) cancer. This analysis aims to explore the correlation between baseline frailty and treatment outcome. Baseline frailty measures were derived from clinical data and included ECOG Performance Status (PS), the GO2 Frailty Score (GO2FS), Geriatric-8 (G8), Cancer and Aging Research Group (CARG) toxicity score and a ‘modified’ Rockwood Clinical Frailty Scale (mCFS). Novel patient-centred composite measure Overall Treatment Utility (OTU) was the primary endpoint. Ordinal logistic regression was undertaken to give odds ratios for poor vs good/intermediate OTU. Secondary endpoints were progression-free and overall survival. Models were adjusted for age, sex, histology, metastases, Trastuzumab and renal/hepatic function. Results In GO2, 514 patients were randomised between three chemotherapy dose-levels; all of these patients were assessed for OTU and are included in this analysis. Worse GO2FS, mCFS and G8 scores all had a statistically significant association with poor (vs good/intermediate) OTU, progression and death, which persisted after adjustment. Adjusted odds ratios for poor OTU amongst those with the worst GO2FS and mCFS and best G8 scores were as follows: 1.85 (95% confidence interval [CI] 1.20–2.88) for GO2FS ≥3 (‘severely frail’), 1.72 (1.19–2.50) for mCFS 5+ (‘frail’) and 0.57 (0.32–1.00) for G8 > 14 (‘normal’). Worse ECOG PS and CARG scores did not have a statistically significant association with poor OTU/progression/death. Conclusion In this study, frailty identified via GO2FS, mCFS and G8 conveyed a statistically significant increased risk of worse treatment outcome in older and frail younger patients with aGO cancer. Frailty assessment provides information over and above PS and should be integrated alongside routine assessments in research and clinical practice. In the absence of prospective data, frailty measures can be derived retrospectively to build the evidence base around optimal care of frailer patients