Snake antivenom for snake venom induced consumption coagulopathy

Background Snake venom induced consumption coagulopathy is a major systemic effect of envenoming. Observational studies suggest that antivenom improves outcomes for venom induced consumption coagulopathy in some snakebites and not others. However, the effectiveness of snake antivenom in all cases of venom induced consumption coagulopathy is controversial. Objectives To assess the effect of snake antivenom as a treatment for venom induced consumption coagulopathy in people with snake bite. Search methods The search was done on 30 January 2015. We searched the Cochrane Injuries Group's Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library), Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid OLDMEDLINE(R), Embase Classic+Embase (OvidSP), three other sources, clinical trials registers, and we also screened reference lists. Selection criteria All completed, published or unpublished, randomised, controlled trials with a placebo or no treatment arm, where snake antivenom was administered for venom induced consumption coagulopathy in humans with snake bites. Data collection and analysis Two authors reviewed the identified trials and independently applied the selection criteria. Main results No studies met the inclusion criteria for this review

Observational Evidence of Wave Ducting and Evanescence in the Mesosphere

A collaborative radar and imaging study of gravity waves over the Hawaiian Islands was performed during October 1993 as part of the Airborne Lidar and Observations of Hawaiian Airglow 1993/Coupling and Dynamics of Regions Equatorial (ALOHA-93/CADRE) campaign to investigate the propagation characteristics of short-period (\u3c1 hour) waves at nightglow altitudes. The horizontal wavelengths and apparent phase speeds of quasi-monochromatic wave events were measured in four separate nightglow emissions using data obtained by a high-resolution CCD imager. This information was correlated with simultaneous MF radar wind measurements over the same height interval (∼80–100 km) to infer intrinsic wave parameters in each case. Correlating the two data sets allowed the determination of the local vertical wavenumber for each event, in particular whether it be real (indicative of freely propagating waves) or imaginary (indicative of ducted or evanescent waves). The results of this study indicate a preponderance of ducted or evanescent waves at 80–100 km during the time of the observations, with up to ∼75% of the events recorded exhibiting ducted or evanescent behavior. Also noted was a tendency for ducted behavior to be more prevalent among waves with shorter horizontal wavelengths, in agreement with Doppler ducting theory. These results suggest that ducted waves are relatively common in the upper mesosphere and lower thermosphere region, at least over the mid-Pacific Ocean. As small-scale waves which are ducted have the potential to travel much longer horizontal distances than freely propagating waves, the frequency of their occurrence should be taken into account in efforts to quantify gravity wave effects at these altitudes

AircraftVerse: A Large-Scale Multimodal Dataset of Aerial Vehicle Designs

We present AircraftVerse, a publicly available aerial vehicle design dataset. Aircraft design encompasses different physics domains and, hence, multiple modalities of representation. The evaluation of these cyber-physical system (CPS) designs requires the use of scientific analytical and simulation models ranging from computer-aided design tools for structural and manufacturing analysis, computational fluid dynamics tools for drag and lift computation, battery models for energy estimation, and simulation models for flight control and dynamics. AircraftVerse contains 27,714 diverse air vehicle designs - the largest corpus of engineering designs with this level of complexity. Each design comprises the following artifacts: a symbolic design tree describing topology, propulsion subsystem, battery subsystem, and other design details; a STandard for the Exchange of Product (STEP) model data; a 3D CAD design using a stereolithography (STL) file format; a 3D point cloud for the shape of the design; and evaluation results from high fidelity state-of-the-art physics models that characterize performance metrics such as maximum flight distance and hover-time. We also present baseline surrogate models that use different modalities of design representation to predict design performance metrics, which we provide as part of our dataset release. Finally, we discuss the potential impact of this dataset on the use of learning in aircraft design and, more generally, in CPS. AircraftVerse is accompanied by a data card, and it is released under Creative Commons Attribution-ShareAlike (CC BY-SA) license. The dataset is hosted at https://zenodo.org/record/6525446, baseline models and code at https://github.com/SRI-CSL/AircraftVerse, and the dataset description at https://aircraftverse.onrender.com/.Comment: The dataset is hosted at https://zenodo.org/record/6525446, baseline models and code at https://github.com/SRI-CSL/AircraftVerse, and the dataset description at https://aircraftverse.onrender.com

Pest control for holly

Published April 1972. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalo

Lessons Learned During Testing Through Commissioning of the Joint Brazil-US SPORT Mission

SPORT is an international partnership mission between Brazil and the United States to study ionospheric space weather processes that occur at low latitudes. Operating a CubeSat on orbit is certainly one of the most exciting milestones of a CubeSat project, but it is only a part of the mission. To be able to achieve this milestone the efforts of the engineering team were focused late in the project on the integration, testing, and delivery followed by the on-orbit commissioning of the observatory. This paper details the major events and lessons learned by the SPORT team during these phases of the project. SPORT experienced a failure of the battery subsystem during environmental testing followed by physical damage during shipping from Brazil to the United States for Launch. However, more than pointing out these problems, solutions, and lessons learned, this paper explains how the international team worked to overcome the issues and finalize the observatory for delivery and launch. After release from the ISS the SPORT team looked forward to the on-orbit observatory operations, first contacts, and the commissioning phase of the observatory, that is also described on this paper

Chemoreceptor responsiveness at sea level does not predict the pulmonary pressure response to high altitude

The hypoxic ventilatory response (HVR) at sea level (SL) is moderately predictive of the change in pulmonary artery systolic pressure (PASP) to acute normobaric hypoxia. However, because of progressive changes in the chemoreflex control of breathing and acid-base balance at high altitude (HA), HVR at SL may not predict PASP at HA. We hypothesized that resting peripheral oxyhemoglobin saturation (SpO2) at HA would correlate better than HVR at SL to PASP at HA. In 20 participants at SL, we measured normobaric, isocapnic HVR (L/min·-%SpO2 -1) and resting PASP using echocardiography. Both resting SpO2 and PASP measures were repeated on day 2 (n=10), days 4-8 (n=12), and 2-3 weeks (n=8) after arrival at 5050m. These data were also collected at 5050m on life-long HA residents (Sherpa; n=21). Compared to SL, SpO2 decreased from 98.6 to 80.5% (P<0.001), while PASP increased from 21.7 to 34.0mmHg (P<0.001) after 2-3 weeks at 5050m. Isocapnic HVR at SL was not related to SpO2 or PASP at any time point at 5050m (all P>0.05). Sherpa had lower PASP (P<0.01) than lowlanders on days 4-8 despite similar SpO2. Upon correction for hematocrit, Sherpa PASP was not different from lowlanders at SL, but lower than lowlanders at all HA time points. At 5050m, whilst SpO2 was not related to PASP in lowlanders at any point (all R2=0.50), there was a weak relationship in the Sherpa (R2=0.16; P=0.07). We conclude that neither HVR at SL nor resting SpO2 at HA correlates with elevations in PASP at HA