Global population growth, technology, and Malthusian constraints: A quantitative growth theoretic perspective

We structurally estimate a two-sector Schumpeterian growth model with endogenous population and finite land reserves to study the long run evolution of global population, technological progress and the demand for food. The estimated model closely replicates trajectories for world population, GDP, sectoral productivity growth and crop land area from 1960 to 2010. Projections from 2010 onwards show a slowdown of technological progress, and because it is a key determinant of fertility costs, significant population growth. By 2100 global population reaches 12 billion and agricultural production doubles, but the land constraint does not bind because of capital investment and technological progress.Funding from the MAVA foundation is gratefully acknowledged

A search for 183-GHz emission from water in late-type stars

A search was made for 183 GHz line emission from water vapor in the direction of twelve Mira and two semiregular variables. Upper limits to the emission are in the range of 2000 to 5000 Jy. It is estimated that thermal emission from the inner regions of late type stellar envelopes will be on the order of ten Jy. Maser emission, according to one model, would be an order of magnitude stronger. From the limited set sampled, the possibility of very strong maser emission at 183 GHz cannot yet be ruled out

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection.

To restrict infection by Legionella pneumophila, mouse macrophages require Naip5, a member of the nucleotide-binding oligomerization domain leucine-rich repeat family of pattern recognition receptors, which detect cytoplasmic microbial products. We report that mouse macrophages restricted L. pneumophila replication and initiated a proinflammatory program of cell death when flagellin contaminated their cytosol. Nuclear condensation, membrane permeability, and interleukin-1beta secretion were triggered by type IV secretion-competent bacteria that encode flagellin. The macrophage response to L. pneumophila was independent of Toll-like receptor signaling but correlated with Naip5 function and required caspase 1 activity. The L. pneumophila type IV secretion system provided only pore-forming activity because listeriolysin O of Listeria monocytogenes could substitute for its contribution. Flagellin monomers appeared to trigger the macrophage response from perforated phagosomes: once heated to disassemble filaments, flagellin triggered cell death but native flagellar preparations did not. Flagellin made L. pneumophila vulnerable to innate immune mechanisms because Naip5+ macrophages restricted the growth of virulent microbes, but flagellin mutants replicated freely. Likewise, after intratracheal inoculation of Naip5+ mice, the yield of L. pneumophila in the lungs declined, whereas the burden of flagellin mutants increased. Accordingly, macrophages respond to cytosolic flagellin by a mechanism that requires Naip5 and caspase 1 to restrict bacterial replication and release proinflammatory cytokines that control L. pneumophila infection

Ractopamine HCl improved cardiac hypertrophy but not poor growth, metabolic inefficiency, or greater white blood cells associated with heat stress in concentrate-fed lambs

Heat stress decreases livestock performance and well-being (Hahn, 1999; Nienaber and Hahn, 2007), causes metabolic dysfunction that decreases growth efficiency (O’Brien et al., 2010), and alters cardiovascular function (Crandall et al., 2008). Each year, heat stress costs the livestock industry up to $2.5 billion (St-Pierre et al., 2003). Ractopamine HCl acts as a nutrient repartitioning agent (Beermann, 2002); classified as a β adrenergic agonist (βAA), it shares pharmacological properties with adrenaline (Beermann, 2002). βAA increase muscle mass and decreases fat deposition through unknown mechanisms (Beermann, 2002). In feedlot cattle, they increase growth efficiency and improve carcass yield and merit (Scramlin et al., 2010; Buntyn et al., 2017), which increases profit and allows more meat to be produced from fewer animals. However, because βAA act via a stress system, it is unclear how the products affect animals under stress conditions. β1AA and β2AA can also cause tachycardia, heart palpitations, and arrhythmias (Sears, 2002). We hypothesize that β1AA combined with heat stress may overstimulate the adrenergic system, resulting is metabolic dysfunction and decreased performance. Sheep are a common model for cattle, and thus, the objective of this study was to determine the impact of ractopamine HCl on health and cardiovascular parameters, growth, and metabolic efficiency in feeder lambs

Tests of the Gravitational Inverse-Square Law below the Dark-Energy Length Scale

We conducted three torsion-balance experiments to test the gravitational inverse-square law at separations between 9.53 mm and 55 micrometers, probing distances less than the dark-energy length scale $\lambda_{\rm d}=\sqrt[4]{\hbar c/\rho_{\rm d}}\approx 85 \mu$m. We find with 95% confidence that the inverse-square law holds ($|\alpha| \leq 1$) down to a length scale $\lambda = 56 \mu$m and that an extra dimension must have a size $R \leq 44 \mu$m.Comment: 4 pages, 6 figure

183 GHz water line variation: An energetic outburst in orion KL

Observations of the 3(13)-2(20) transition of water vapor in the direction of Ori MC1 in 1980 February show a 50% flux increase and an apparent additional red shift of approximately 2 km/s relative to the line observed in 1977 December. From a detailed examination of the amplitude and frequency calibration, it appears unlikely that the effect is due to systematic error. The increase is attributed to the appearance of a new component at a velocity of 12 km/s with respect to the local standard of rest. The new component also has broad wings. Increased emission from a region in the high-velocity core of Ori MC1 can be due either to additional far-IR radiation to pump the 1983 GHz transition or to a change in the physical conditions in the gas. Statistical equilibrium calculations using the large-velocity-gradient formalism were carried out to develop a model for the emission. The calculations support a model in which the gas in the region of enhanced emission is hotter than the dust. The temporal coincidence between the 183 GHZ increase and the 22 GH1 water maser outburst suggests a common, impulsive cause, which has heated the gas in a part of the HV source, enhancing the emission in both transitions

Body composition estimated by bioelectrical impedance analyses is diminished by prenatal stress in neonatal lambs and by heat stress in feedlot wethers

Body composition correlates to carcass value in livestock, which makes the ability to accurately estimate body composition in the live animal beneficial (Berg and Marchello, 1994). Bioelectrical impedance analysis (BIA) is a clinical tool used to assess body composition in humans (Lukaski et al., 1985), but its use in livestock has been minimal. Lean and fat content contribute to profitability for livestock producers, and poor body composition can be caused by stress that occurs either during in utero development (De Blasio et al., 2007) or during postnatal growth (Boyd et al., 2015). Maternal hyperthermia-induced placental insufficiency (Brown et al., 2015) and sustained maternal inflammation (Cadaret et al., 2018) are two established causes of intrauterine growth restriction (IUGR). IUGR-born animals are characterized by asymmetrical growth restriction that alters lifelong body composition due to impaired muscle growth capacity (Yates et al., 2018). In addition, acute heat stress during periods of peak postnatal growth can alter body composition in livestock (Boyd et al., 2015). We postulate that BIA can detect these changes in the live animal. Thus, the objective of this study was to determine whether BIA measurements can predict changes to body composition in live neonatal lambs exposed to intrauterine stress and in heat-stressed feedlot lambs

Possible Molecular States of Ds∗Dˉs∗D^{*}_s\bar{D}^{*}_s System and Y(4140)

The interpretation of Y(4140) as a $D^{*}_s\bar{D}^{*}_s$ molecule is studied dynamically in the one boson exchange approach, where $\sigma$, $\eta$ and $\phi$ exchange are included. Ten allowed $D^{*}_s\bar{D}^{*}_s$ states with low spin parity are considered, we find that the $J^{PC}=0^{++}$, $1^{+-}$, $0^{-+}$, $2^{++}$ and $1^{--}$ $D^{*}_s\bar{D}^{*}_s$ configurations are most tightly bound. We suggest the most favorable quantum numbers are $J^{PC}=0^{++}$ for Y(4140) as a $D^{*}_s\bar{D}^{*}_s$ molecule, however, $J^{PC}=0^{-+}$ and $2^{++}$ can not be excluded. We propose to search for the $1^{+-}$ and $1^{--}$ partners in the $J/\psi\eta$ and $J/\psi\eta'$ final states, which is an important test of the molecular hypothesis of Y(4140) and the reasonability of our model. The $0^{++}$ $B^{*}_s\bar{B}^{*}_s$ molecule is deeply bound, experimental search in the $\Upsilon(1S)\phi$ channel at Tevatron and LHC is suggested.Comment: 13 pages,2 figure

Water quality in the central Nebraska basins, Nebraska, 1992-95

This report is intended to summarize major findings that emerged between 1992 and 1995 from the water-quality assessment of the Central Nebraska Basins Study Unit and to relate these findings to water-quality issues of regional and national concern. The information is primarily intended for those who are involved in waterresource management. Indeed, this report addresses many of the concerns raised by regulators, water-utility managers, industry representatives, and other scientists, engineers, public officials, and members of stakeholder groups who provided advice and input to the USGS during this NAWQA Study-Unit investigation. Yet, the information contained here may also interest those who simply wish to know more about the quality of water in the rivers and aquifers in the area where they live. Land use in central Nebraska appears to affect water quality significantly; streams in rangelands generally had fewer occurrences and smaller concentrations of pesticides than did streams in croplands where corn and soybeans were planted extensively. Subbasins with greater proportions of rangeland, such as the Dismal River, had negligible herbicide concentrations. The largest pesticide concentrations were in storm runoff following pesticide applications. Because some pesticide concentrations may exceed the U.S. Environmental Protection Agency’s (USEPA) drinking-water Maximum Contaminant Levels (MCLs) in storm runoff, the timing and intensity of rainfall has implications for drinking-water supplies. Pesticides in streams from storm runoff may enter alluvial aquifers as a consequence of ground-water withdrawals. Sites with degraded water chemistry commonly had degraded physical habitats as well. Streamflow regulation of the Platte River has affected water quality through habitat alterations that are deleterious to native species. The combination of degraded physical and chemical environments commonly resulted in structurally simple fish communities. CONTENTS National Water-Quality Assessment Program .. 1 Summary of major issues and findings... 2 Environmental setting and hydrologic conditions.... 4 Major issues and findings ... 6 Nitrate content in water is related to agricultural land management 6 Agricultural activities potentially affect the management of public water supplies . 8 Water quality in the Platte River alluvial aquifer may be affected by surface-water quality in areas of ground-water withdrawals .. 10 Aquatic environments potentially are altered by human activities... 12 Aquatic and migratory species are affected directly by changes in the physical characteristics of the Platte River .. 14 Water-quality conditions in anational context ... 16 Study design and data collection .. 20 Summary of compound detections and concentrations ... 22 References . 28 Glossary 3

Rubidium atomic funnel

A low-velocity beam of rubidium atoms is produced from a two-dimensional magneto-optic trap or atomic funnel. Atoms from a thermal beam are slowed by chirped laser cooling and then loaded into the funnel. The cold atoms are ejected by moving molasses formed with frequency-shifted laser beams. The resultant atomic beam has a controllable velocity in the range of 3 to 10 m/s, a temperature of 500 μK, and a flux of 1010 atoms/s