17 research outputs found
Polymorphism: an evaluation of the potential risk to the quality of drug products from the FarmĂĄcia Popular Rede PrĂłpria
Tax revenue as an automatic fiscal stabiliser - a South African perspective
The many practical economic and political difficulties encountered in
discretionary fiscal stabilisation policy highlight the potential benefits of
allowing automatic fiscal stabilisers to operate over the cycle. This article
investigates the relevance of tax revenue as an automatic fiscal stabiliser in the
South African economy by an empirical analysis of its role and impact since the
1970s. The study finds that cyclical changes in tax revenue are relatively small
and provide no significant evidence of automatic stabilisation; however, the
potential of this tool as an effective automatic fiscal stabiliser in South Africa
cannot be overlooked as results show a high correlation between the output gap
and automatic stabiliser estimates. Automatic fiscal stabilisers were employed
symmetrically over the cycle and results showed that automatic fiscal stabilisers
became increasingly important towards the end of the sample period
New possibilities to improve air quality in low income housing and reduce greenhouse gasses
Helically coiled solar cavity receiver for micro-scale direct steam generation
Concentrated solar systems have a large potential for power generation and water pumping in rural off-grid settlements with a high solar irradiance resource. With the use of a solar dish concentrator, superheated steam can be directly generated in a solar cavity receiver. Volumetric expanders show promise for micro-scale power production (below 1 kW). However, naturalistic experimental investigations of micro-scale direct steam generation using a solar dish is limited. In this work, a low-cost helically coiled cavity receiver and a novel solar concentrator manufactured from off-the-shelf components are experimentally investigated for steam generation at water pressures of above 3 bar. Working fluid temperatures were measured throughout the coil length and pressures were measured at the inlet and outlet of the receiver coil. Using a concentrator with a total incident area of 2.70 m2 and a water flow rate of 0.294 g/s, the working fluid captured 861 W of heat with an outlet temperature of 343 °C at an average solar irradiance of 757 W/m2. The average thermal efficiencies of the collector and receiver were determined to be 42% and 50%, respectively, for the testing period. Furthermore, the average second-law efficiency was 12%. Flow patterns within the coil were investigated by considering the temperature differences between the coil surface and the working fluid. A heat loss model was developed that could predict the steady-state heat loss rate with an accuracy of 97%. The observations made during the study and the results obtained highlight important design aspects that need to be considered in future work.The National Research Foundation (NRF) of South Africa, the Technology Innovation Agency (TIA) of South Africa and the Department of Science and Innovation (DSI).https://www.elsevier.com/locate/apthermeng2021-12-06hj2021Mechanical and Aeronautical Engineerin
An auditory profile of sclerosteosis
OBJECTIVE : To characterise auditory involvement secondary to excessive craniotubular bone growth in individuals
with sclerosteosis in South Africa.
METHODS : This cross-sectional study assessed the auditory profile of 10 participants with sclerosteosis. An
auditory test battery was used and results for each ear were recorded using descriptive and comparative analyses.
RESULTS : All participants presented with bilateral, mixed hearing losses. Of the 20 ears, hearing loss was moderate
in 5 per cent (n = 1), severe in 55 per cent (n = 11) and profound in 40 per cent (n = 8). Airâbone gaps were smaller
in older participants, although the difference was not statistically significant (p > 0.05). Computed tomography
scans indicated pervasive abnormalities of the external auditory canal, tympanic membrane, middle-ear space,
ossicles, oval window, round window and internal auditory canal. Narrowed internal auditory canals
corresponded to poor speech discrimination, indicative of retrocochlear pathology and absent auditory brainstem
response waves.
CONCLUSION : Progressive abnormal bone formation in sclerosteosis involves the middle ear, the round and oval
windows of the cochlea, and the internal auditory canal. The condition compromises conductive, sensory and
neural auditory pathways, which results in moderate to profound, mixed hearing loss.http://journals.cambridge.org/action/displayJournal?jid=JLOhb201
Function of formula-like poetic devices in Lesoro's modern praise poem Dithoko tsa profesa W.M. Kgware
Indirect enzyme-linked immunosorbent assay for the detection of antibody against Rift Valley fever virus in domestic and wild ruminant sera
An indirect enzyme-linked immunosorbent assay (I-ELISA) for the detection of specific IgG immunoglobulins against Rift Valley fever virus (RVFV) was validated in-house. A total of 3055 sera from sheep (n = 1 159), goats (n = 636), cattle (n = 203), African buffalo (n = 928), and other wild ruminants (n = 129), including eland, kudu, and black wildebeest, was used. Sera from domestic ruminants were collected in West (n = 10), South (n = 1 654) and East Africa (n = 334), and sera from wild ruminants (n = 1 064) were collected in South Africa. In addition, 136 sera from eight experimentally RVFV-infected sheep, taken during a period of 28 days post infection (dpi), were used to study the kinetics of RVFV antibody production. Field sera were tested by the serum neutralization (VN) test and experimental sera by VN and haemagglutination-inhibition (HI) test. Based on VN test results, negative sera were regarded as reference controls from RVFV-free, and positive sera were regarded as reference controls from RVFV-infected subpopulations of animals. ELISA data were expressed as the percentage positivity (PP) of an internal high positive control. The two-graph receiver operating characteristics approach was used for the selection and optimization of I-ELISA cut-offs including the miscIassification costs term and Youden index (J). In addition, cut-off values were determined as the mean plus two-fold standard deviation of the result observed with the RVFV-free subpopulations. Established optimal cut-offs were different for each of the data sets analyzed, and ranged from 1.65 PP (buffalo) to 9.1 PP (goats). At the cut-off giving the highest estimate of combined measure of diagnostic accuracy (highest J value), the I-ELISA test parameters were determined as follows: (1) Diagnostic sensitivity (%): cattle--84.31, buffalo--94.44, sheep--98.91, goats--99.18. (2) Diagnostic specificity (%): cattle--99.34, buffalo--98.28, sheep--99.16, goats--99.23 and other game ruminants--99.26. In the group of RVFV-experimentally infected sheep, seroconversion in all individuals was detected by VN on 4-6 dpi, by HI on 5-7 dpi, and by I-ELISA on 6-7 dpi. All tests showed the same kinetic pattern of immunological response. Antibody levels were low for a very short period before increasing to high titres, after which it was easily detectable by all tests. Compared to traditional tests, the lower sensitivity of I-ELISA in the detection of the earliest stage of immunological response may be practically insignificant, particularly when this assay is used in population-based, disease-surveillance programmes. The high sensitivity and specificity of I-ELISA established in this study, especially for the statistically more representative subpopulations of animals tested, seem to support this prediction. Test parameters determined in this study should, however, be regarded as in-house diagnostic decision limits, for which further updating is recommended, particularly for specimens from other countries, and preferably by applying a standardized method for sampling of new subpopulations of animals to be targeted by the assay.The articles have been scanned with a HP Scanjet 8300; 600dpi, saved in TIFF format.
Adobe Acrobat v.9 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format