A Teaching Trial of Music Class Room Learning Collaborated with "Special Activities": A case Study of Teaching Practice of "School Play Day" for the 5th Grade Children

本研究の目的は、特別活動の領域に属する学芸会の実践を取り上げ、子どもの表現力を高めていくための効果的な手立てを探ることにある。研究の方法として、2つの仮説を設定し、特別活動に属する「学校行事」と教科書に属する「音楽」との連帯を図り、実践を行った。①教師が一人ひとりの子どもに応じた支援をすれば、子どもの表現意欲を高めることができる。②振り返る機会を設定すれば、子どもは自ら音楽にかかわり、表現力を高めることができる。仮説の有効性を検証するために、抽出児2名の学習課程と意識の変容を観察し、分析した。その結果、仮設1に対しては朱書きや対話、仮設2に対しては自己評価や録音・録画を使用したことが、子どもの表現力を高めるのに有効に働いていることが判明し、2つの仮説の有効性が検証された。The pupose of this study is to examine effective methods to develop children's musical expression ability in "school play day" of "special activities". The following hypotheses were proposed and put into actual teaching. 1) With individual supports during the process of exercises, children will practice more eagerly to refine their expression. 2) By looking back former activities by themselves, children's musical expression ability will be more developed. To examine these hypotheses, two children were chosen, their learning processes were recorded and analyzed. The following results were obtained: 1) by adding teacher's comments on portfolio and frequent talking by a teacher to each child on his/her performance, children were push to exercise more actively. 2) Children's self evaluation and records worked effectively to deepen their expression. Thus these hypotheses were valid to develop children's musical expression ability

A study of Songs in "Hyojun Shihan Gako Ongaku Kyokasho"(1938) Edited by Kurosawa and Ogawa

本稿の目的は、黒澤隆朝・小川一朗編『標準師範学校音楽教科書』（1938）の歌曲を概観することによって、国定師範学校教科書が発行される直後の検定済教科書における歌曲の特徴と傾向を明らかにすることである。『師範音楽　本科用巻一』（1943）との比較を通して、以下の3点が明らかとなった。①『標準師範学校音楽教科書』は、歌曲の他、器楽、鑑賞、音楽理論、音楽基礎の分野を含み、編纂された教科書である。②8割近くの歌曲は、西洋の作品ないしは西洋の民謡であり、それらの歌詞は原曲の翻案か、新しく作られた日本語の詩である。③ミリタリズム志向の歌曲教材には、4/4拍子、　、弱起、長調の行進曲が適用されている。The purpose of this study is to examine the characteristics of songs in "Hyojun Shihan Gako Ongaku Kyokasho (Music Standard Textbook for normal schools)"(1938) authorized by the Ministry of Education normal schools. The following results were obtained by comparing with "Shihan Ongaku"(1943) designated by the goverment: 1) "Hyojun Shihan Gako Ongaku Kyokasho" was a textbook which contains songs materials, instrumental music, listening, music theory, and sight singing. 2) About 80 percent of the song materials were occupied by Western folk songs and songs composed by the European composers. However, lyrics of these songs were adapted from the originals or newly written in Japanese. 3) Regarding military-oriented materials, Western marches with 4/4, doted rhythm, beginning in up-beat, and in major key were adopted

Down regulation by a low-zinc diet in gene expression of rat prostatic thymidylate synthase and thymidine kinase

<p>Abstract</p> <p>Background</p> <p>Zinc has a wide spectrum of biological activities and its deficiency is related to various abnormalities of cell metabolism.</p> <p>Methods</p> <p>Wistar male rats, at age of 4 weeks, were fed a low-zinc diet for six weeks. The levels of bromodeoxyuridine incorporated into the prostatic DNA and the mRNA expression levels of prostate thymidylate synthase and thymidine kinase were examined.</p> <p>Result</p> <p>The low-zinc diet caused a marked reduction in the body growth and organ weights, resulted in a low hematopoiesis, hypo-albuminemia and hypocholesterolemia. Although there were few differences in plasma biochemical markers, plasma levels of luteinizing hormone and testosterone were reduced by the low-zinc diet. Bromodeoxyuridine-immunoreactive (S-phase) cells and mRNA expression levels of thymidylate synthase and thymidine kinase in the prostate cells were markedly affected by the low-zinc diet.</p> <p>Conclusion</p> <p>A low-zinc diet appears to reduce the body growth and organ weights including prostate, causing low plasma levels of luteinizing hormone and testosterone and reduction in prostate DNA replication in growing-rats.</p

Impact of helical elongation of symmetric oxa[n]helicenes on their structural, photophysical, and chiroptical characteristics

Salem M.S.H., Sharma R., Suzuki S., et al. Impact of helical elongation of symmetric oxa[n]helicenes on their structural, photophysical, and chiroptical characteristics. Chirality 36, e23673 (2024); https://doi.org/10.1002/chir.23673.The adjustment of the main helical scaffold in helicenes is a fundamental strategy for modulating their optical features, thereby enhancing their potential for diverse applications. This work explores the influence of helical elongation (n = 5–9) on the structural, photophysical, and chiroptical features of symmetric oxa[n]helicenes. Crystal structure analyses revealed structural variations with helical extension, impacting torsion angles, helical pitch, and packing arrangements. Through theoretical investigations using density functional theory (DFT) calculations, the impact of helical extension on aromaticity, planarity distortion, and heightened chiral stability were discussed. Photophysical features were studied through spectrophotometric analysis, with insights gained through time-dependent DFT (TD-DFT) calculations. Following optical resolution via chiral high-performance liquid chromatography (HPLC), the chiroptical properties of both enantiomers of oxa[7]helicene and oxa[9]helicene were investigated. A slight variation in the main helical scaffold of oxa[n]helicenes from [7] to [9] induced an approximately three-fold increase in dissymmetry factors with the biggest values of|glum| of oxa[9]helicene (2.2 × 10−3) compared to|glum|of oxa[7]helicene (0.8 × 10−3), findings discussed and supported by TD-DFT calculations

Fragment of an endogenous inhibitor produced in Escherichia coli for calcium-activated neutral protease (CANP) retains an inhibitory activity

AbstractA C-terminal fragment of an endogenous rabbit liver inhibitor for calcium-activated neutral protease (CANP) was produced in Escherichia coli and its inhibitory activity was examined after purification. The truncated inhibitor (373 amino acid residues), which contains two internal repeat structures, inhibits 2 mol CANP whereas the native liver inhibitor (639 residues), containing four internal repeat structures, inhibits 4 mol CANP. This supports the hypothesis that the repeating unit is the functional unit of inhibition. The results also indicate that post-translational modification of the inhibitor is not essential for inhibition

Learning about View of Life and Death, Especially from Children’s Death Caused by Natural Disasters in the City of Manado, Province of North Sulawesi,Indonesa

This is a study conducted by our research group about the psychological background of local people in Manado,Indonesia. Interviews were made to a group of locals concerning their approach to death and consequent state of mind focused on their religious beliefs on Obon festival,conversation with spirits,reincarnation and the influence of holy men. We recognized the fantasy they believed that spirit comes back from afterworld in the ceremony. In addition,we understood the event that spirit returns from afterworld once a year and“offering” is common sense. However,these custom had difference depended on regions and their social rank. As a result,these local people were difficult to share the common sense about the event. Reporting to spirit and conversation to spirit were common events in whole regions in Indonesia,but the quality might be different. Especially,idea about reincarnation was modified among young and old generations.調査・事例等報