Predictive Values for N. meningitidis Diagnosis

<p>PVPs and NPVs for the diagnosis of N. meningitidis serogroup A (A) and serogroup W135 (B), according to prevalence. PVP is represented by the purple line with open circles, and NPV by the blue line with filled circles.</p

RDT Results by Serogroup

<p>Results of RDT₁ and RDT₂ are shown for each N. meningitidis serogroup.</p

Prevalence (%) of anaemia according to the absence or to the presence of several potential risk factors at the baseline data collection

<p>Prevalence (%) of anaemia according to the absence or to the presence of several potential risk factors at the baseline data collection</p

Evolution of the prevalence (%) of the main morbidity indicators between initial survey and re-assessment one year later (paired analysis)

*<p>McNemar's chi² for paired samples</p>†<p>No = absent, Yes = present</p>‡<p>No = Not infected or light-intensity infection, Yes = heavy-intensity infection</p>§<p>No = no lesion, Yes = at least one lesion</p>¶<p>No = no impact or light impact, Yes = moderate to very severe impact</p

Performance of the IgM RDT assay on laboratory-confirmed leptospirosis and controls.

<p>Performance of the IgM RDT assay on laboratory-confirmed leptospirosis and controls.</p

Positive and negative predictive values (PPV, NPV) of the Vertical Flow Rapid Diagnostic Test.

<p>Values calculated using 187 positive and 221 negative serum specimens.</p

Comparison of four rapid diagnostic tests on randomly-selected serum samples.

<p>NA: Not Applicable.</p>*<p>LR+: Positive Likelihood Ratio – [95% CI].</p>†<p>LR−: Negative Likelihood Ratio – [95% CI].</p>‡<p>DOR: Diagnostic Odds Ratio – [95% CI].</p><p>Sensitivity (%), number of positive rapid diagnostic test among patients with serological evidence (MAT) of leptospirosis (n = 72) – [95% CI].</p><p>Specificity (%), negative rapid diagnostic test among serum samples from patients with no serological evidence (MAT) of leptospirosis (n = 72) – [95% CI].</p

Comparative predictive values of the Rapid Diagnostic Test and of a commercial test.

<p>Positive and negative predictive values for the diagnosis of leptospirosis using the IgM Rapid Diagnostic Test evaluated in this study and a commercial lateral flow IgM assay were calculated using 72 positive and 72 negative serum specimens randomly selected from New Caledonian specimens.</p

Comparative kinetics of antibody detection using MAT and RDT.

*<p>D0 is the day of onset of symptoms as declared by the patient.</p