301 research outputs found

    Reducing the health effect of particles from agriculture

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    This autumn, the European Union (EU) Parliament will have a crucial vote on the future of air pollution policy in Europe. For discussion is a commission proposal for new national emission ceilings, as amended by the European Parliament Environment Committee in July, 2015. The proposed emission ceilings cover not only emissions of primary, directly emitted particulate matter but also emissions from precursor gases. These gases include ammonia, sulphur dioxide, and nitrogen oxides, which react in the atmosphere to form solid (particulate) ammonium sulphates and nitrates

    Reviews

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    The following publications have been reviewed by the mentioned authors;Welsh Crafts by Mary Eirwen Jones, reviewed by Roy NashA Source Book of Picture Making by Henry Pluckrose, reviewed by R. HartApproaches to Drawing by Leo Walmsley, reviewed by John EgglestonMoulded and Slip Cast Pottery and Ceramics by David Cowley, reviewed by Michael PaffardPainting by John Lancaster, reviewed by R. N. MacGregorDesign Resource Sheets by R. N. Billington and J. R. Jeffrey, reviewed by Dick SuttonEnamelling on Metal,Ā Oppi. Intracht, reviewed by J. N. AtkinsProcesses by Jack Bainbridge, reviewed by Michael SayerArtists and People by Su Braden, reviewed by Roy ShawMake Your Own Musical Instrument by Stuart Dalby, reviewed by Eric DecorteDesign in General Education by John Harahan, reviewed by Bernard AylwardPainting Without a Brush by Roy Sparkes, reviewed by John LancasterBuilding Craft Equipment by A. Jay and Carol W. Abrams, reviewed by S. R. BlundellPyrography by Berhand Havez and Jean-Claude Varlet, reviewed by Paul Kin

    Internet banking acceptance model: Cross-market examination

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    This article proposes a revised technology acceptance model to measure consumersā€™ acceptance of Internet banking, the Internet Banking Acceptance Model (IBAM). Data was collected from 618 university students in the United Kingdom and Saudi Arabia. The results suggest the importance of attitude, such that attitude and behavioral intentions emerge as a single factor, denoted as ā€œattitudinal intentionsā€ (AI). Structural equation modeling confirms the fit of the model, in which perceived usefulness and trust fully mediate the impact of subjective norms and perceived manageability on AI. The invariance analysis demonstrates the psychometric equivalence of the IBAM measurements between the two country groups. At the structural level, the influence of trust and system usefulness on AI vary between the two countries, emphasizing the potential role of cultures in IS adoption. The IBAM is robust and parsimonious, explaining over 80% of AI

    Collusion, Profitability and Welfare: Theory and Evidence

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    In a differentiated oligopoly model with free entry, the static welfare loss from collusion is larger the lower the entry cost, the larger the market size and the higher the degree of product differentiation. The cartel overcharge is larger the lower the entry cost and the larger the market size, and is independent of the degree of product differentiation. These theoretical results are consistent with evidence from a natural experiment of policy reform, the introduction of cartel law in the UK in the late 1950s. Price-cost margins declined after the breakdown of cartels in low-capital and larger-sized industries relative to capital-intensive and smaller-sized ones. There is weaker evidence of a fall in price-cost margins in consumer good and advertising-intensive relative to producer good and low-advertising industries. Crucially, these effects are not observed for industries not affected by the cartel law. A comparison of these findings with evidence on the incidence of collusion suggests that the welfare loss from collusive pricing may often be smaller in industries where cartels tend to form than in those where collusion is more difficult to sustain

    The Effect of Lattice Vibrations on Substitutional Alloy Thermodynamics

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    A longstanding limitation of first-principles calculations of substitutional alloy phase diagrams is the difficulty to account for lattice vibrations. A survey of the theoretical and experimental literature seeking to quantify the impact of lattice vibrations on phase stability indicates that this effect can be substantial. Typical vibrational entropy differences between phases are of the order of 0.1 to 0.2 k_B/atom, which is comparable to the typical values of configurational entropy differences in binary alloys (at most 0.693 k_B/atom). This paper describes the basic formalism underlying ab initio phase diagram calculations, along with the generalization required to account for lattice vibrations. We overview the various techniques allowing the theoretical calculation and the experimental determination of phonon dispersion curves and related thermodynamic quantities, such as vibrational entropy or free energy. A clear picture of the origin of vibrational entropy differences between phases in an alloy system is presented that goes beyond the traditional bond counting and volume change arguments. Vibrational entropy change can be attributed to the changes in chemical bond stiffness associated with the changes in bond length that take place during a phase transformation. This so-called ``bond stiffness vs. bond length'' interpretation both summarizes the key phenomenon driving vibrational entropy changes and provides a practical tool to model them.Comment: Submitted to Reviews of Modern Physics 44 pages, 6 figure

    Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse

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    Following a screen for neuromuscular mouse mutants, we identified ostes, a novel N-ethyl N-nitrosourea-induced mouse mutant with muscle atrophy. Genetic and biochemical evidence shows that upregulation of the novel, uncharacterized transient receptor potential polycystic (TRPP) channel PKD1L2 (polycystic kidney disease gene 1-like 2) underlies this disease. Ostes mice suffer from chronic neuromuscular impairments including neuromuscular junction degeneration, polyneuronal innervation and myopathy. Ectopic expression of PKD1L2 in transgenic mice reproduced the ostes myopathic changes and, indeed, caused severe muscle atrophy in Tg(Pkd1l2)/Tg(Pkd1l2) mice. Moreover, double-heterozygous mice (ostes/+, Tg(Pkd1l2)/0) suffer from myopathic changes more profound than each heterozygote, indicating positive correlation between PKD1L2 levels and disease severity. We show that, in vivo, PKD1L2 primarily associates with endogenous fatty acid synthase in normal skeletal muscle, and these proteins co-localize to costameric regions of the muscle fibre. In diseased ostes/ostes muscle, both proteins are upregulated, and ostes/ostes mice show signs of abnormal lipid metabolism. This work shows the first role for a TRPP channel in neuromuscular integrity and disease
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