Baroreflex sensitivity (BRS) determined by the sequence method, pre and 30-min and 60-min post exercise in Caucasian and Chinese individuals.

<p>(a) BRS(up-up) showed a significant race by time interaction. *P<0.05 (b) There was no race-by-time interaction for the change in BRS(dn-dn).</p

CONSORT Flow diagram.

<p>CONSORT Flow diagram.</p

Change value from baseline for (a) LnHF, natural logarithm of high frequency (b) nHF, normalized high frequency (c) nLF, normalized low frequency (d) LF/HF, LF/ HF ratio (e) LnRMSSD, natural logarithm of RMSSD (f) HR, heart rate (g) BRS(up-up), Baroreflex sensitivity up-up, at 30-min and 60-min after exercise.

<p>Data are reported as mean ± SE (#significant race-by-time interaction; *significant change compared with baseline).</p

Subject characteristics.

<p>Subject characteristics.</p

Exercise hemodynamic and water intake.

<p>Exercise hemodynamic and water intake.</p

A schematic of the study design showing the procedures for each visit.

<p>Subjects underwent testing to determine peak oxygen uptake (VO_2peak) and a blood draw prior to randomization to placebo or histamine blockade (Visit 1). The order in which the blockade/placebo (visits 2 or 3) were administered was randomized. During study visits 2 and 3, cardiovascular (CV) measurements were obtained at rest and at 30 min, 60 min and 90 min post-exercise (during recovery).</p

Systemic vascular conductance (SVC) at baseline and at 30 min, 60 min and 90 min following aerobic exercise in the control condition (A) and H₁R and H₂R blockade condition (B).

<p>* Significant blockade by time interaction. § Significant main effect of time (p<0.05). ‡ BL had significantly lower SVC compared to CA at PRE in the blockade condition (p<0.05).</p