Метафора в публицистике: репрезентация вариантов языковой картины мира

Метафора как универсальное средство концептуализации действительности в том или ином виде свойственна всем языковым картинам мира независимо от национально-культурной принадлежности. В статье рассматриваются особенности политических метафор, включённых в публицистическую картину мира, которая является разновидностью языковой картины мира и представляет часть концептуальной картины мир

Trip around the three-membered cycles syntheses

peer reviewe

Synthesis of a new family of acyclic nucleoside phosphonates, analogues of TPases transition states

International audienceA 6-step procedure was developed for the synthesis of a new family of acyclic nucleoside phosphonates (ANPs), "PHEEPA" [(2-pyrimidinyl-2-(2-hydroxyethoxy)ethyl)phosphonic acids] in overall yields ranging from 4.5% to 32%. These compounds, which possess on one side a hydroxy function and on the other side a phosphonate group, can be considered either as potential antiviral agents or as transition state analogues of nucleoside phosphorylases such as thymidine phosphorylase

Synthesis of Unnatural Phosphonosugar Analogues.

International audienceThe first synthesis of new cyclic phosphonates (phostones), analogues of pentafuranoses containing a phosphorus atom in place of the anomeric carbon in the deoxyribose and deoxyxylose series, is described. Two methods, of respectively six and seven steps, were developed in parallel, and each gave the racemic phosphonosugars in good yields. Compounds analogous to the alpha and beta anomers were isolated and fully characterized by NMR spectroscopy