3,931 research outputs found

    Two-dimensional heterogeneous photonic bandedge laser

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    We proposed and realized a two-dimensional (2D) photonic bandedge laser surrounded by the photonic bandgap. The heterogeneous photonic crystal structure consists of two triangular lattices of the same lattice constant with different air hole radii. The photonic crystal laser was realized by room-temperature optical pumping of air-bridge slabs of InGaAsP quantum wells emitting at 1.55 micrometer. The lasing mode was identified from its spectral positions and polarization directions. A low threshold incident pump power of 0.24mW was achieved. The measured characteristics of the photonic crystal lasers closely agree with the results of real space and Fourier space calculations based on the finite-difference time-domain method.Comment: 14 pages, 4 figure

    Rapid Detection Strategies for the Global Threat of Zika Virus: Current State, New Hypotheses, and Limitations

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    The current scenario regarding the widespread Zika virus (ZIKV) has resulted in numerous diagnostic studies, specifically in South America and in locations where there is frequent entry of travelers returning from ZIKV-affected areas, including pregnant women with or without clinical symptoms of ZIKV infection. The World Health Organization, WHO, announced that millions of cases of ZIKV are likely to occur in the United States of America in the near future. This situation has created an alarming public health emergency of international concern requiring the detection of this life-threatening viral candidate due to increased cases of newborn microcephaly associated with ZIKV infection. Hence, this review reports possible methods and strategies for the fast and reliable detection of ZIKV with particular emphasis on current updates, knowledge and new hypotheses that might be helpful for medical professionals in poor and developing countries that urgently need to address this problem. In particular, we emphasize liposome-based biosensors. Although these biosensors are currently among the less popular tools for human disease detection, they have become useful tools for the screening and detection of pathogenic bacteria, fungi and viruses because of their versatile advantageous features compared to other sensing devices. This review summarizes the currently available methods employed for the rapid detection of ZIKV and suggests an innovative approach involving the application of a liposome-based hypothesis for the development of new strategies for ZIKV detection and their use as effective biomedicinal tools

    Comparative effects of norepinephrine and vasopressin on internal thoracic arterial graft flow after off-pump coronary artery bypass grafting

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    ObjectiveVasoconstrictors such as norepinephrine and vasopressin are commonly used to raise the blood pressure during myocardial revascularization. The internal thoracic artery is commonly used for coronary artery grafting because of its long-term patency. However, the internal thoracic artery is a living conduit that responds to vasoactive substances. The objective of this study was to measure change in internal thoracic arterial flow after infusion of norepinephrine or vasopressin.MethodsForty-one patients undergoing elective off-pump coronary artery bypass grafting participated in this study. After the median sternotomy, the left internal thoracic artery was dissected with a pedicle and grafted to the left anterior descending artery. After all anastomoses were performed and hemodynamic parameters were stable, the grafted internal thoracic arterial blood flow was measured by transit time flowmeter on the distal portion of the graft as a baseline. Norepinephrine or vasopressin was then infused until mean arterial pressure was increased to 20% of baseline. Graft flow and hemodynamic variables were measured when mean arterial pressure reached the intended level.ResultsBaseline grafted internal thoracic arterial flows were similar (norepinephrine 57.1Ā Ā± 17.7 mL mināˆ’1, vasopressin 66.0Ā Ā± 34.3 mL mināˆ’1). With norepinephrine, flow increased significantly relative to baseline (77.2Ā Ā± 31.0 mL mināˆ’1); with vasopressin, it remained unchanged (68.3Ā Ā± 37.0 mL mināˆ’1).ConclusionsFor patients needing vasopressor support after coronary artery bypass grafting, norepinephrine appeared superior to vasopressin because of increased internal thoracic arterial flow

    Estimation of Corrosion-Free Life for Concrete Containing Ground Granulated Blast-Furnace Slag under a Chloride-Bearing Environment

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    The rate of chloride transport by diffusion in concrete containing ground granulated blast-furnace slag (GGBS) was mathematically estimated to predict the corrosion-free service life of concrete structures exposed to seawater environment. As a factor to corrosiveness of steel embedment, replacement ratio of GGBS was selected, accounting for 25 and 50% to total binder. As a result, it was found that an increase in the GGBS content resulted in an increase in the chloride binding capacity, which would give rise to a lower chloride diffusion rate, thereby reducing the risk of chloride-induced corrosion. When it comes to the sensitivity of parameters to service life, the effective diffusivity showed a marginal influence on serviceability, irrespective of GGBS contents while surface chloride content and critical threshold concentration revealed more crucial factors to long term chloride diffusion. As the GGBS replacement increased, the variation in service life has become less influential with changing parameters. Substantially, GGBS concrete at high replacement ratio enhanced the service life due to a combination of dense pore structure and enhanced chloride binding capacity

    DETERMINATION OF OPTIMAL LOCATIONS OF AMPHIBIAN ECO-DUCTS BY USING GENETIC ALGORITHMS: A CASE STUDY OF ODAESAN NATIONAL PARK IN KOREA

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    There are currently no systematic guidelines for placing the animal passes for wildlife to cross safely the human-made roads. This study presents a mathematical model that determines the optimal locations for amphibian eco-ducts by using a genetic algorithm. The study area is route no. 6 of Odaesan National Park in Korea, and the animals of focus are amphibians. The most crucial factor, the migration distance between amphibian road-kill sites and proposed eco-duct sites, was considered for determination of the optimal locations of amphibian eco-ducts. They were determined by calculating the minimum total distances associated with this factor near the road-kill sites. The model determined 69 optimal locations of ecoduct sites in eight sections of route no.6

    Ab initio study of the effect of water adsorption on the carbon nanotube field-effect transistor

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    We perform density-functional calculations to investigate the effect of adsorbed water molecules on carbon nanotubes (CNTs). Noting that the H2 O molecule has much wider energy gap than the CNT, we find that the charge transfer between them is negligible. We discuss that several recent publications, which claimed a substantial electron transfer from the water molecule to the CNT, have been based on incautious interpretations of the Mulliken population analysis. We suggest that the effect of humidity on nanotube devices may be attributed to various indirect effects enhanced by water vapors, rather than the carrier generations by the physisorbed H2 O molecules.open292
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