Fungicides have been used for over 200 years to protect plants from damage by fungi, but today fungicidal resistance is very common among potato pathogens and it is difficult to control. The best and intensively studied example is metalaxyl resistance in Pytophthora infestans. Causes are many to get pathogen resistance against the fungicides like intensive use or misuse of it, repeated application of same fungicides, etc. Hence, it is today’s need to find out the different strategies like different cultural practices, use of bio-agents, use of green chemicals, elimination of disease source, etc. to manage this fungicidal resistance. There are also alternative ways like increasing host resistance, use of new molecules, etc. that can be adopted to reduce the risk of fungicidal resistance