16,212 research outputs found

    Tree level spontaneous R-symmetry breaking in O'Raifeartaigh models

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    We show that in O'Raifeartaigh models of spontaneous supersymmetry breaking, R-symmetries can be broken by non-zero values of fields at tree level, rather than by vacuum expectation values of pseudomoduli at loop level. As a complement of the recent result by Shih, we show that there must be a field in the theory with R-charge different from zero and two in order for R-symmetry breaking to occur, no matter whether the breaking happens at tree or loop level. We review the example by CDFM, and construct two types of tree level R-symmetry breaking models with a wide range of parameters and free of runaway problem. And the R-symmetry is broken everywhere on the pseudomoduli space in these models. This provides a rich set of candidates for SUSY model building and phenomenology.Comment: 8 pages; v2: major revision to section 6; v3: minor revision and typos; v4: typos, published version; v5: fix Latex syntax error, published versio

    On the nature of the lightest scalar resonances

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    We briefly review the recent progresses in the new unitarization approach being developed by us. Especially we discuss the large NcN_c ππ\pi\pi scatterings by making use of the partial wave SS matrix parametrization form. We find that the σ\sigma pole may move to the negative real axis on the second sheet of the complex ss plane, therefore it raises the interesting question that this `σ\sigma' pole may be related to the σ\sigma in the linear σ\sigma model.Comment: Talk presented by Zheng at ``Quark Confinement and Hadron Spectroscopy VI'', 21--25 Sept. 2004, Cagliari, Italy. 3 pages with 2 figure

    ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells.

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    BACKGROUND: Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation of viral protein in the ER by viral infection. Then, unfolded protein response (UPR) is activated to alleviate the stress. Zika virus (ZIKV) is a mosquito-borne flavivirus and its infection causes microcephaly in newborns and serious neurological complications in adults. Here, we investigated ER stress and the regulating model of UPR in ZIKV-infected neural cells in vitro and in vivo. METHODS: Mice deficient in type I and II IFN receptors were infected with ZIKV via intraperitoneal injection and the nervous tissues of the mice were assayed at 5 days post-infection. The expression of phospho-IRE1, XBP1, and ATF6 which were the key markers of ER stress were analyzed by immunohistochemistry assay in vivo. Additionally, the nuclear localization of XBP1s and ATF6n were analyzed by immunohistofluorescence. Furthermore, two representative neural cells, neuroblastoma cell line (SK-N-SH) and astrocytoma cell line (CCF-STTG1), were selected to verify the ER stress in vitro. The expression of BIP, phospho-elF2α, phospho-IRE1, and ATF6 were analyzed through western blot and the nuclear localization of XBP1s was performed by confocal immunofluorescence microscopy. RT-qPCR was also used to quantify the mRNA level of the UPR downstream genes in vitro and in vivo. RESULTS: ZIKV infection significantly upregulated the expression of ER stress markers in vitro and in vivo. Phospho-IRE1 and XBP1 expression significantly increased in the cerebellum and mesocephalon, while ATF6 expression significantly increased in the mesocephalon. ATF6n and XBP1s were translocated into the cell nucleus. The levels of BIP, ATF6, phospho-elf2α, and spliced xbp1 also significantly increased in vitro. Furthermore, the downstream genes of UPR were detected to investigate the regulating model of the UPR during ZIKV infection in vitro and in vivo. The transcriptional levels of atf4, gadd34, chop, and edem-1 in vivo and that of gadd34 and chop in vitro significantly increased. CONCLUSION: Findings in this study demonstrated that ZIKV infection activates ER stress in neural cells. The results offer clues to further study the mechanism of neuropathogenesis caused by ZIKV infection

    Handling Computation Hardness and Time Complexity Issue of Battery Energy Storage Scheduling in Microgrids by Deep Reinforcement Learning

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    With the development of microgrids (MGs), an energy management system (EMS) is required to ensure the stable and economically efficient operation of the MG system. In this paper, an intelligent EMS is proposed by exploiting the deep reinforcement learning (DRL) technique. DRL is employed as the effective method for handling the computation hardness of optimal scheduling of the charge/discharge of battery energy storage in the MG EMS. Since the optimal decision for charge/discharge of the battery depends on its state of charge given from the consecutive time steps, it demands a full-time horizon scheduling to obtain the optimum solution. This, however, increases the time complexity of the EMS and turns it into an NP-hard problem. By considering the energy storage system’s charging/discharging power as the control variable, the DRL agent is trained to investigate the best energy storage control method for both deterministic and stochastic weather scenarios. The efficiency of the strategy suggested in this study in minimizing the cost of purchasing energy is also shown from a quantitative perspective through programming verification and comparison with the results of mixed integer programming and the heuristic genetic algorithm (GA)

    Anisotropic spin fluctuations and multiple superconducting gaps in hole-doped Ba_0.7K_0.3Fe_2As_2: NMR in a single crystal

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    We report the first ^{75}As-NMR study on a single crystal of the hole-doped iron-pnictide superconductor Ba_{0.7}K_{0.3}Fe_2As_{2} (T_c = 31.5 K). We find that the Fe antiferromagnetic spin fluctuations are anisotropic and are weaker compared to underdoped copper-oxides or cobalt-oxide superconductors. The spin lattice relaxation rate 1/T_1 decreases below T_c with no coherence peak and shows a step-wise variation at low temperatures, which is indicative of multiple superconducting gaps, as in the electron-doped Pr(La)FeAsO1−x_{1-x}Fx_{x}. Furthermore, no evidence was obtained for a microscopic coexistence of a long-range magnetic and superconductivity
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