Antidromic vasodilatation and the migraine mechanism

Despite the fact that an unprecedented series of new discoveries in neurochemistry, neuroimaging, genetics and clinical pharmacology accumulated over the last 20 years has significantly increased our current knowledge, the underlying mechanism of the migraine headache remains elusive. The present review article addresses, from early evidence that emerged at the end of the nineteenth century, the role of ‘antidromic vasodilatation’ as part of the more general phenomenon, currently defined as neurogenic inflammation, in the unique type of pain reported by patients suffering from migraine headaches. The present paper describes distinctive orthodromic and antidromic properties of a subset of somatosensory neurons, the vascular- and neurobiology of peptides contained in these neurons, and the clinical–pharmacological data obtained in recent investigations using provocation tests in experimental animals and human beings. Altogether, previous and recent data underscore that antidromic vasodilatation, originating from the activation of peptidergic somatosensory neurons, cannot yet be discarded as a major contributing mechanism of the throbbing head pain and hyperalgesia of migraine

Photoelectrochemical characteristics of cells with dyed and undyed nanoporous p-type semiconductor CuO electrodes

ArticleJOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY. 194(2-3): 143-147 (2008)journal articl

Observation of four-fold azimuthal angle dependence in the terahertz radiation power of (100) p-InAs

The azimuthal angle dependence of the terahertz (THz) radiation power of (100) p-type InAs under 1-T magnetic field is presented. Results exhibited four-fold symmetry for the s-polarized THz radiation power. Moreover, the two-fold symmetry for the p-polarized THz radiation was modified to four-fold symmetry for a 1-T applied magnetic field. A tentative explanation regarding a magnetic field-enhanced L-valley carrier scattering is proposed. The actual physical origin of these results is currently under investigation. ©2006 IEEE