Formulation and Evaluation of Microemulsion Containing Miconazole Nitrate

The aim of the present research is to formulate a microemulsion containing miconazole nitrate as it provides various advantages over conventional dosage form. It also put forward the idea for the formulation of microemulsion containing miconazole nitrate with the use of varying surfactant and co- surfactants   with an objective to increase the better drug loading, high transparency, high thermodynamic stability, better bioavailability and ease of preparation. Miconazole nitrate is hydrophobic imidazole antifungal agent. The studies show that it is highly effective in the topical treatment of fungal infections. Due to the presence of both lipophilic and hydrophilic domains, a wide range of lipophilic and hydrophilic domains are incorporated in these systems