14 research outputs found

    Violence in South African adolescents:a road to recovery

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    South African adolescents are at risk for exposure to violence victimisation and a significant proportion of them engage in violence perpetration. The experiences of victimisation and perpetration can take a significant toll on adolescents’ psycho-social development and lead to long-term impact on health and functioning in adulthood. Given the pressing situation of violence in South Africa and the importance to promote positive functioning in adolescents so they grow up to be responsible individuals and drive the country’s socio-economic development, a needs assessment was conducted. Specifically, quantitative methods were used to examine the risk and protective factors associated with adolescents’ experiences of victimisation and perpetration, as well as the negative impact of victimisation on adolescents’ psychological functioning and health risk behaviours. Moreover, qualitative methods were used to explore the protective factors that enhance resilience in adolescents living in high-violence communities. The results may inform the development of interventions to prevent the experiences of victimisation and perpetration in South African adolescents, and help them thrive and attain positive developmental outcomes

    SNP rs3803264 polymorphisms in THSD1 and abnormally expressed mRNA are associated with hemorrhagic stroke

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    BackgroundThrombospondin Type 1 Domain Containing Protein 1 (THSD1) has been suggested to be a new regulator of endothelial barrier function in the angiogenesis process, preserving vascular integrity. We sought to characterize the association of THSD1 genetic variants and mRNA expression with the risk of hemorrhagic stroke (HS) with population-based evidence.MethodsA case–control study was conducted with 843 HS cases and 1,400 healthy controls. A cohort study enrolled 4,080 participants free of stroke at baseline in 2009 and followed up to 2022. A synonymous variant, the main tag SNP rs3803264 of the THSD1 gene, was genotyped in all subjects, and peripheral leukocyte THSD1 mRNA expression was detected using RT-qPCR in 57 HS cases and 119 controls.ResultsIn the case–control study, rs3803264 AG/GG variations are associated with a decreased risk of HS with odd ratio (OR) and 95% confidence interval (CI) of the dominant model of 0.788 (0.648–0.958), p = 0.017. In addition, rs3803264 and dyslipidemia had a multiplicative interaction [OR (95% CI) = 1.389 (1.032, 1.869), p = 0.030]. In the cohort study, a similar association strength of rs3803264 dominant model and the risk of HS was observed with the incidence rate ratio (IRR) of 0.734 and p-value of 0.383. Furthermore, the risk of HS showed a non-linear as THSD1 mRNA expression increased (p for non-linearity <0.001). For the subjects without hypertension, we observed THSD1 mRNA expression had a negative correlation with systolic blood pressure (SBP; ρ = −0.334, p = 0.022).ConclusionSNP rs3803264 polymorphisms in THSD1 are associated with the decreased risk of HS and interacted with dyslipidemia, and a non-linear association was observed between THSD1 mRNA expression and the risk of HS

    It's the thought that counts: Trait self-control is positively associated with well-being and coping via thought control ability

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    In the present study, we reason that the ability to keep unwanted thoughts and intrusions at bay – thought control ability – might explain part of the relationship between trait self-control and positive psychological outcomes. We predict that the ability to keep unwanted thoughts at bay causes people high in trait self-control to report higher subjective well-being (Study 1), and makes them to be more likely to cope with stressful life events in an adaptive rather than maladaptive manner (Study 2). Two cross-sectional studies among healthy individuals were conducted (Study 1 n = 284; 70% female; Mage = 22.15 years; Study 2 n = 210, 65.7% female, Mage = 28.07) in which trait self-control, thought control ability, subjective well-being (study 1), and coping styles (study 2) were measured. Additionally, we investigated the mediating role of thought control ability and the conditional effect of gender on this mediation. The results of Study 1 indicate that trait self-control is positively related to subjective well-being. Moreover, thought control ability fully mediated the relationship between trait self-control and subjective well-being, and this effect was particularly strong for women. In Study 2, trait self-control was positively associated with adaptive forms of coping, but negatively with maladaptive coping. Moreover, thought control ability partially mediated the relationship between trait self-control and both types of coping, with stronger results for women than for men. These results suggest that trait self-control affects positive life outcomes in part through an ability to keep unwanted thoughts at bay, thereby facilitating a focus on goal pursuit

    Developmental Assets in South African Adolescents Exposed to Violence: a Qualitative Study on Resilience

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    Violence exposure is associated with psychological and behavioural maladjustment in adolescents. Yet, not all adolescents exposed to violence experience negative symptoms. Resilience is an outcome that is in part determined by multiple protective factors, or developmental assets, that protect adolescents from the negative influence of encountered stressors and allow them to attain positive developmental outcomes. A qualitative study was conducted to acquire an in-depth understanding of the developmental assets across different layers in the ecological system that promote positive psychological and behavioural functioning in South African adolescents exposed to violence. Semi-structured individual interviews were conducted with a multi-ethnic group (black, white, and people of mixed heritage) of South African adolescents (boy: n = 17; girl: n = 13; age: 14-19 years) from seven schools in Cape Town. Adolescents reported both internal and external assets that helped them adaptively cope with violence exposure. The internal assets entailed individual characteristics and skills, including commitment to learning, positive values, positive identity, social competencies, and emotional insight. The external assets were boundaries and expectations, social support from adolescents' peers, family, school, and community, and adolescents' constructive use of time. The findings of the study may inform strengths-based interventions to enhance emotional and behavioural skills in adolescents at risk for violence exposure. Moreover, involving key stakeholders in the interventions from major developmental domains can be particularly helpful to optimise the social support that are needed for adolescents to be resilient

    Violence typologies and sociodemographic correlates in South African adolescents: a three-wave cross-sectional study

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    Background: Violence victimisation and violence perpetration may co-occur in adolescents. Understanding the sociodemographic correlates of the independent and joint profiles of victimisation and perpetration may inform preventive interventions. This study examined the associations of sociodemographic factors with four violence typologies, namely, 1) non-involvement in both victimisation and perpetration, 2) victims only, 3) perpetrators only, and 4) victim-perpetrators. Trends in the prevalence of the four violence typologies over the three survey years were also examined. Methods: We used data from the three nationally representative South African Youth Risk Behaviour Surveys conducted in 2002, 2008, and 2011 and included a multi-ethnic sample of adolescents (n = 30,007; boy: 46.9%, girls: 53.1%; M age = 16 years, SD = .06). Results: The sample consisted of 8030 (30.8%) adolescents who had non-involvement in both victimization and perpetration, 8217 were victims only (29.8%), 2504 were perpetrators only (9.0%), and 7776 were victimperpetrators (24.6%). Logistic regression analyses showed that being a girl increased the odds of non-involvement (OR: 1.47, 99% CI: 1.36–1.58) and being victims only (OR: 1.90, 99% CI: 1.76–2.05). Being a boy increased the odds of being perpetrators only (OR: 0.42, 99% CI: 0.37–0.47) and victim-perpetrators (OR: 0.51, 99% CI: 0.47–0.55). Adolescents who did not have an absent mother had higher odds of non-involvement (OR: 0.78, 99% CI: 0.62–0.97). Lower monthly allowance increased the odds of victimisation only (OR: 0.99, 99% CI: 0.97–1.00), whereas higher monthly allowance increased the odds of perpetration only (OR: 1.05, 99% CI: 1.03–1.08). Trend analysis showed that between 2002 to 2011, there was an increase in the prevalence of non-involvement in adolescents (p .05). Conclusions: Sociodemographic factors are uniquely associated with different violence typologies suggesting the need for tailored interventions to target adolescents with differed risks to violence victimisation and perpetration. Strengthening family relations, particularly between mother and child, may protect adolescents from the experiences of victimisation and perpetration

    Violence typologies and sociodemographic correlates in South African adolescents: a three-wave cross-sectional study

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    Background: Violence victimisation and violence perpetration may co-occur in adolescents. Understanding the sociodemographic correlates of the independent and joint profiles of victimisation and perpetration may inform preventive interventions. This study examined the associations of sociodemographic factors with four violence typologies, namely, 1) non-involvement in both victimisation and perpetration, 2) victims only, 3) perpetrators only, and 4) victim-perpetrators. Trends in the prevalence of the four violence typologies over the three survey years were also examined. Methods: We used data from the three nationally representative South African Youth Risk Behaviour Surveys conducted in 2002, 2008, and 2011 and included a multi-ethnic sample of adolescents (n = 30,007; boy: 46.9%, girls: 53.1%; M age = 16 years, SD = .06). Results: The sample consisted of 8030 (30.8%) adolescents who had non-involvement in both victimization and perpetration, 8217 were victims only (29.8%), 2504 were perpetrators only (9.0%), and 7776 were victimperpetrators (24.6%). Logistic regression analyses showed that being a girl increased the odds of non-involvement (OR: 1.47, 99% CI: 1.36–1.58) and being victims only (OR: 1.90, 99% CI: 1.76–2.05). Being a boy increased the odds of being perpetrators only (OR: 0.42, 99% CI: 0.37–0.47) and victim-perpetrators (OR: 0.51, 99% CI: 0.47–0.55). Adolescents who did not have an absent mother had higher odds of non-involvement (OR: 0.78, 99% CI: 0.62–0.97). Lower monthly allowance increased the odds of victimisation only (OR: 0.99, 99% CI: 0.97–1.00), whereas higher monthly allowance increased the odds of perpetration only (OR: 1.05, 99% CI: 1.03–1.08). Trend analysis showed that between 2002 to 2011, there was an increase in the prevalence of non-involvement in adolescents (p .001), a decrease in the prevalence of victims only (p .05) and victim-perpetrators (p .001), and no changes in the prevalence of perpetrators only (p > .05). Conclusions: Sociodemographic factors are uniquely associated with different violence typologies suggesting the need for tailored interventions to target adolescents with differed risks to violence victimisation and perpetration. Strengthening family relations, particularly between mother and child, may protect adolescents from the experiences of victimisation and perpetration

    Exposure to violence across multiple contexts and health risk behaviours in South African adolescents: the moderating role of emotion dysregulation

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    Objective: The association between violence exposure and health risk behaviours in South African adolescents, and the moderating role of emotion dysregulation were investigated. Design: A multiethnic sample of adolescents (N¼925: boy: 47.3%, girl: 52.7%, M age ¼ 16 years, SD¼1.54) completed a survey. Main outcome measures: Violence exposure across different contexts (home-, school-, community-, political victimisation), emotion dysregulation (inability to regulate sadness and anger) and a composite measure of health risk behaviours (smoking, substance use, risky sexual behaviour) were examined. Results: Boys reported more risk behaviours than girls, t (844) ¼ 5.25, p<0.001. Direct community victimisation was a predictor for boys’ risk behaviours, B¼0.22, p<0.001. Indirect school victimisation and direct community victimisation were predictors for girls’ risk behaviours, B’s ¼ 0.19, p’s < 0.01. Girls reported higher emotion dysregulation than boys, t (748) ¼ _2.95, p<0.01. Only for girls, emotion dysregulation moderated the associations of indirect home victimisation, B¼16, p<0.01, and direct community victimisation, B¼15, p<0.05, with risk behaviours. Conclusion: Interventions may target emotion regulation skills, particularly for girls, to enhance resilience to the negative effects of violence on behaviours
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