User accessible tissue sample image database system and method

The invention is a medical application of content based image retreival system which is capable of searching through a large image database to find images relevant to user queries based upon visual features such as color texture and shape. these feature values are generally descirbed indirectly through the use of example images since it is inconvenient and inherently difficult for humans to express queries in terms of low level visual characteristics. In other wors, the user describes the desired cocept for retrieval by providing relevant image examples. for instance, a user wishing to find images of various flowers can convey the desired feature values by choosing an image of a flower as a query image. Can be used for matching gene expressions, cat MRI and PET scans, and identifying and diagnosing various diseases

Methods and materials for stimulating proliferation of stem cells (DIV)

Disclosed herein are methods and materials for influencing proliferation of stem cells. Specifically exemplified herein are compositions comprising cerium oxide nanoparticles which can be used to stimulate proliferation of stem cells under common culture conditions, or which can be utilized to improve therapeutic outcomes

Mesenchymal stem cells with increased developmental potency by expressing Nanog

CON filing for non-elected claims 7 and 1

Methods for increasing potency of adult mesenchymal stem cells

Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage

Use of modified pyrimidine compounds to promote stem cell migration and proliferation (UIC-A)

This invention provides methods for preparing novel mammalian multipotent stem cells (MSCs), compositions thereof, and methods of preparing and administering the cells

Methods and materials for increasing potency of cells (CON 1)

Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage

Compositions for treating or delaying the onset of hair loss (US)

Disclosed herein are novel methods and compositions for treating and/or preventing hair loss in patients. Specifically exemplified herein are compositions containing a modified pyrimidine that are topically applied to a scalp of an patient. Typically, the patient has androgenic alopecia, alopecia greata, postpartum alopecia or telogen effluvium

Methods for modifying stem cell characteristics

We propose a method of expanding stem cells and dedifferentiating cells by cultruing cells with cell cultrue extracts of embryonic stem cellas and or extracts from a regenerating limb. We demonstrated that co cultureing human bone marrow mesenchymal stem cells with sections of a lizard tail or mouse embryonic stem cells increases the stemness of the Msc. This allows for the creation of a cell cultruing system containing expgenous factors that facilitate increased expression of stem cells genes and dedifferentiation

Stem cell banking system

The creation of specialized embryonic stem cell lines is a valuable tool for research and discovery. However, the large cost of production and ethical concerns over ESC lines limits their future development. We propose the creation of specialized cell types from somatic cells