5 research outputs found
Primary multicentric cutaneous epithelioid angiosarcoma
Cutaneous epithelioid angiosarcoma is a rare malignant vascular tumor,
most commonly affecting elderly men, and is usually located on the
extremities. We report a case of an 81-year-old lady who presented with
two ulcerated plaques over the right temporal and parietal scalp of 1
year duration. The right submaxillary and submandibular lymph nodes
were enlarged and tender. Computed tomography (CT) scan of the head
showed soft tissue swelling over parietal and temporal areas and there
was no intracranial extension. Ultrasonogram of the abdomen showed
hyperechoic areas in liver suggestive of secondaries. Histopathology of
the skin lesion showed the dermis and subcutis composed of clusters of
atypical epithelioid cells with vesicular nuclei, prominent nucleoli
and eosinophilic cytoplasm with increased mitotic figures.
Immunohistochemical staining revealed CD-31, 33, 34 and vimentin
positivity, while cytokeratin was negative confirming the diagnosis of
epitheloid angiosarcoma. This case report highlights the unusual
occurrence of multicentric epitheloid angiosarcoma on the scalp with
secondaries in the liver