Chronic myeloid leukemia in case of Klinefelter syndrome

Klinefelter syndrome (KS) is a sex chromosome disorder and has been reported to be associated with increased risk for malignancies. We report a 22-year-old male patient who was diagnosed to have chronic myeloid leukemia in chronic phase. Bone marrow cytogenetic examination revealed karyotype 47, XXY, t (9; 22)(q34, q11) suggestive of KS with presence of Philadelphia chromosome. The patient was treated with oral imatinib mesylate (400 mg/day). Complete hematological response was achieved after 2 months of therapy. The bcr-abl/abl transcript percentage measured from peripheral blood at baseline, 1 and 2 years after imatinib were 97%, 1.99%, 0.007%, respectively. He remains in complete hematological and major molecular remission after 2 years of continued imatinib therapy

Eco-friendly vaccination: Tackling an unforeseen adverse effect

The beginning of 2021 was marked by COVID-19 vaccination campaigns worldwide. The pace of production has been accelerated, in order to meet global needs and achieve the desired levels of immunization of the general population against COVID-19 within the year. Several debatable aspects of this endeavor, from logistics to health promotion have been addressed so far. However, the environmental repercussions of plastic syringes used for massive COVID-19 vaccinations are yet to be discussed. This article delves into the impact of the increasing medical waste, associated with massive COVID-19 vaccination on the environment, citing the practices followed and its possible solutions. The increasing production of nonbiodegradable materials is inevitably going to affect the world we live in. .Moreover, this article highlights the importance of developing sustainable methods of vaccination and disposal, providing examples and evidence based recommendations. Along with educating the unaware proportion of the population, there is a need to develop sustainable and recyclable products for a better tomorrow