Simulation and Analysis of Biogas operated Double Effect GAX Absorption Refrigeration System

A thermodynamic simulation of a double effect generator heat exchanger absorption refrigeration cycle using biogas as source of energy has been carried out. The binary mixture considered in the present investigation was NH3 – H2O (Ammonia - Water). This simulation was performed in order to investigate the effect of the temperature and pressure of the high temperature generator and the pressure of evaporator have over the Coefficient of Performance (COP) for a constant condenser and absorber temperatures. The basic parameters at various state points of the cycle was computed using standard correlations. The solution circulation rates and volume of biogas required for operation of the cycle are analysed for the variations in operating parameters at the high temperature generator and evaporator

Physical Model Study on Tandem Breakwater with Concrete Cube Armour

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

THE REPERTORY GRID INTERVIEW OF A DEPRESSED PATIENT

The construct system of a patient of Depression is investigated with the Rank Order Repertory Grid Technique, using principal component analysis to analyse the grid matrix. The investigation helps test clinical judgments and hypotheses concerning the patient and also suggests new directions for further clinical enquiry. This case study demonstrates how the grid technique can make possible a more comprehensive understanding of the cognitive processes of the patient

Synthesis based on cyclohexadienes. Part 24. A new total synthesis of pupukean-2-one and a facile entry to copa and ylanga type sesquiterpene skeletons

A novel tandem 5-exo-trig allyl and 3-exo-trig radical cyclisation and rearrangement to copa and ylanga type sesquiterpene skeletons from easily prepared cyclohexadienes is reported. A new total synthesis of pupukean-2-one 8, which belongs to a novel class of sesquiterpenes, involving a 5-exo-trig allyl radical cyclisation as the key step is also reported

RAPID, METHOD FOR DETERMINATION OF METFORMIN AND CANAGLIFLOZIN IN PLASMA BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETER, APPLICATION TO BIOEQUIVALENCE STUDY

Objective: The objective of the study was to develop and validate a rapid selective bioanalytical method for the simultaneous determination of metformin and canagliflozin in plasma by liquid chromatography-tandem mass spectrometer (LC-MS/MS) to facilitate bioequivalence study sample analysis. Stock solutions and spiking solutions were prepared accurately in methanol and 80% methanol in water, respectively. Methods: Chromatography monitored using Analyst 1.6.2 software. Method was found selective, no matrix effect, reproducible and consistent recovery, accuracy, precision, and stable in aqueous as well as extracted/matrix samples. Method found linear over the range 10–2000 ng/ml for metformin and 30–6000 ng/ml for canagliflozin. The method is successfully applied to analyze samples collected in a bioequivalence study after administration of metformin/canagliflozin 1000/150 mg to 24 healthy male volunteers. Results: Extraction was carried out using a simple solid phase extraction using mobile phase elution. 5 μl sample delivered as injection volume in 1.000 ml/min isocratic mobile phase flow on turbo ion electron spray technique for positive mode on API 4000 MS. Discussion: Chromatography achieved within 3 min using a mobile phase containing acetonitrile and 10 mM ammonium formate buffer in a ratio of 70:30 on chromolith C18 analytical column. Q1/Q3 are 130.1/70.1, 136.3/77.1, 462.2/267.2 (with ammonium adduct), and 466.4/267.1 for metformin, metformin D6, canagliflozin, and canagliflozin D4, respectively. Conclusion: Rapid, sensitive method for the simultaneous estimation of metformin and canagliflozin in plasma by LC-MS/MS is successfully developed, validated and applied to analyze 960 unknown samples of a bioequivalence study. Incurred sample reanalysis was revealed great reproducibility

Synthesis based on cyclohexadienes. Part 23. Total synthesis of 5-epi-pupukean-2-one

A new strategy for the construction of the isotwistane skeleton is reported from easily available cyclohexadienes which involves stereoselective alkylation of a bicyclooctenone derivative and a decarboxylative 5-exo-trig radical cyclisation as the key steps in the total synthesis of 5-epi-pupukean-2-one

Water-saving Rice Production Technologies in Krishna Western Delta Command of Andhra Pradesh – An Economic Analysis

The economic analysis of water-saving rice production technologies, viz. system of rice intensification (SRI), semi-dry and rotational irrigation vis-à-vis farmers’ practice has been carried out based on the study executed in Modukuru pilot area of Guntur district of Andhra Pradesh. Among the three water-saving rice production technologies analyzed, the total cost of cultivation has been recorded highest in SRI (Rs 58645/ha), followed by rotational (Rs 47140/ha) and semi-dry (Rs 39321/ha). But, the per hectare yield has been found highest in SRI (6.85 t), followed by semi-dry (6.66 t) and rotational (6.2 t), inferring that all the three technologies have recorded higher yields over farmers’ practice of 5.5 t/ha. However, the net returns and B-C ratio are maximum in semi-dry (Rs 43,484/ha; 1.11), followed by rotational (Rs 30,085; 0.64) and SRI (Rs 26,466/ha; 0.45) methods. Similarly, the water-use efficiency has been found highest in SRI (8.53 kg/ ha-mm), followed by semi-dry (8.02 kg/ha-mm) and rotational (7.33 kg/ ha-mm) methods, while the water-use efficiency benefit (Rs/ha-mm) has been recorded maximum in semi-dry (52.39), followed by SRI (42.08) and rotational (35.56) methods. With the initiation of Andhra Pradesh Water Management Project, Bapatla, the area under semi-dry rice cultivation has been found increasing over a period of four years, from 0.6 ha in 2004-2005 to 22 ha in 2007 -2008.Agricultural and Food Policy,

Development of indigenous column flotation technology at NML for the beneficiation of low-grade ores

NML Madras Centre has designed and developed indigenous automated flotation columns as part of its long term R&D program on the utilization of low-grade ores of India. Both laboratory size and semi-commercial flotation columns were extensively field tested in different mineral processing plants owned by Hindustan Copper Limited, Hindustan Zinc Limited, Kudremukh Iron Ore Company Limited, Sociedade De Fomento Industrial Limited, Bharat Gold Mines Limited, Gujarat Mineral Development Corporation Limited and Indian Rare Earths Limited for the beneficiation of copper, lead and zinc, iron, gold, fluorspar and sillimanite. State-of-the-art equipment was incorporated in both laboratory and semi-commercial flotation columns. Advantages of column flotation technology over conventional flotation machines and salient features of the NML flotation column were discussed in the present paper. Flotation test results obtained both by flotation column and conventional cells were compared. The paper also highlights the potential of column flotation technology in achieving better metallurgical results

Studies on the Beneficiation of Barite

Barite is extensively used as drilling mud in oil exploration operations. Beneficiation of barite by flotation was investigated using cationic and anionic collectors. Commercially available fatty amines such as Armoflote 17 and Liquid B50 were tried as collectors to float gangue minerals (reverse flotation) whereas oleic acid was used for direct flotation of barite. Effect of collector concentration on flotation was studied and the results were discussed. Barite concentrate assaying 96% BaSO4 with less than 1% SiO2 could be obtained by single stage flotation using cationic collectors. Zeta-potential measurements were conducted to study the interaction of cationic collectors on silica and anionic collector on barite. While cationic collectors were found to adsorb on silica by electrostatic interaction, oleic acid was found to adsorb on barite by chemisorption. Advantage of reverse flotation over direct flotation technique was discussed

Synthesis based on cyclohexadienes. Part 22. Formal syntheses of patchouli alcohol and norpatchoulenol

The preparation of 6-endo-formyl-1,3,3-trimethylbicyclo[2.2.2]octan-2-one 7 and 6-endo-acetyl-1,3,3-trimethylbicyclo[2.2.2]octan-2-one 8, the two key intermediates for the synthesis of patchouli alcohol 1 and norpatchoulenol 2, is reported by a simple and short method from 2-methylbenzoic acid