Adapting Sequence Models for Sentence Correction

In a controlled experiment of sequence-to-sequence approaches for the task of sentence correction, we find that character-based models are generally more effective than word-based models and models that encode subword information via convolutions, and that modeling the output data as a series of diffs improves effectiveness over standard approaches. Our strongest sequence-to-sequence model improves over our strongest phrase-based statistical machine translation model, with access to the same data, by 6 M2 (0.5 GLEU) points. Additionally, in the data environment of the standard CoNLL-2014 setup, we demonstrate that modeling (and tuning against) diffs yields similar or better M2 scores with simpler models and/or significantly less data than previous sequence-to-sequence approaches.Comment: EMNLP 201

Identification and characterisation of 17 polymorphic candidate genes for response to parasitic nematode (Trichostrongylus tenuis) infection in red grouse (Lagopus lagopus scotica)

Acknowledgements This study was funded by a BBSRC studentship (MA Wenzel) and NERC Grants NE/H00775X/1 and NE/D000602/1 (SB Piertney). We are grateful to Jacob Hoglund for providing willow grouse samples, Mario Roder, Keliya Bai, Marianne James, Matt Oliver, Gill Murray-Dickson, Francois Mougeot and Jesus Martınez-Padilla for help with fieldwork, and all grouse estate factors, owners and keepers, most particularly Alistair Mitchell, Shaila Rao, Christopher Murphy, Richard Cooke and Fred Taylor, for providing access to estate game larders.Peer reviewedPostprin

A transcriptomic investigation of handicap models in sexual selection

We are grateful to D. Calder and T. Helps for access to study sites, and G. Murray-Dickson and M. Oliver for help with fieldwork and comments on manuscript drafts. This work was funded by NERC grant NE/D000602/1 (SBP), a NERC advanced fellowship (FM) and a BBSRC studentship (MAW)Peer reviewedPostprin

Effect of Hydrogen Bonding on the Deformation Frequencies of the Hydroxyl Group in Alcohols

The effects of hydrogen bonding on the infrared spectra of aliphatic alcohols have been studied in the range 4000 to 350 cm—1. Twenty‐six alcohols were investigated of which 10 were primary, 7 were branched primary, 6 were secondary, and 3 were tertiary. Attention was concentrated on the region of the spectrum between 1500 cm—1 and 350 cm—1 where the deformation vibrations of the OH group occur. Spectra were obtained of the alcohols (a) in dilute solution in nonpolar solvents, (b) in the liquid state, and (c) in the vapor state, the degree of association being followed by observation of the well‐known effect of hydrogen bonding in the OH stretching vibration near 3.0μ. Methanol, ethanol, and hexanol‐1 were also investigated after deuteration of the OH group. All the alcohols exhibited a broad diffuse association band with a maximum near 650 cm—1. This has been assigned to the out‐of‐plane deformation vibration of the H atom in the COH group. All the alcohols also exhibited a broad association band which usually had 2 maxima near 1410 cm—1 and 1330 cm—1. This band (which appears to have been missed by previous workers) is assigned to the in‐plane deformation vibration of the H atom in the COH group. The corresponding monomeric band varies between 1200 cm—1 and 1330 cm—1 in undeuterated alcohols and between 870 cm—1 and 930 cm—1 in deuterated alcohols. There is in addition a very narrow association band which lies near 1100 cm—1 in primary and secondary alcohols and near 1165 cm—1 in tertiary alcohols. This is assigned to the effect of hydrogen bonding on the skeletal vibrations, which involve stretching of the CO bond. It appears that the effects of hydrogen bonding on the deformation motions of the OH group are quite complex and that steric effects, rotational isomerism, and interaction with C ☒ H deformation frequencies may all be involved to some extent.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71317/2/JCPSA6-24-3-559-1.pd

The Effect of Hydrogen Bonding on the Hindered Rotation of the Hydroxyl Group in Alcohols

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69594/2/JCPSA6-20-12-1977-1.pd

Can a native rodent species limit the invasive potential of a non-native rodent species in tropical agroforest habitats?

BACKGROUND Little is known about native and non-native rodent species interactions in complex tropical agro-ecosystems. We hypothesised that the native non-pest rodent Rattus everetti may be competitively dominant over the invasive pest rodent Rattus tanezumi within agroforests. We tested this experimentally by using pulse removal for three consecutive months to reduce populations of R. everetti in agroforest habitat and assessed over 6-months the response of R. tanezumi and other rodent species. RESULTS Following removal, R. everetti individuals rapidly immigrated into removal sites. At the end of the study period, R. tanezumi were larger and there was a significant shift in their microhabitat use with respect to the use of ground vegetation cover following the perturbation of R. everetti. Irrespective of treatment, R. tanezumi selected microhabitat with less tree canopy cover, indicative of severely disturbed habitat, whereas, R. everetti selected microhabitat with a dense canopy. CONCLUSION Our results suggest that sustained habitat disturbance in agroforests favours R. tanezumi, whilst the regeneration of agroforests towards a more natural state would favour native species and may reduce pest pressure in adjacent crops. In addition, the rapid recolonisation of R. everetti suggests this species would be able to recover from non-target impacts of short-term rodent pest control

Pronounced genetic structure and low genetic diversity in European red-billed chough (Pyrrhocorax pyrrhocorax) populations

Conservation Genetics August 2015, Volume 16, Issue 4, pp 1011–1012 Erratum to: Pronounced genetic structure and low genetic diversity in European red-billed chough (Pyrrhocorax pyrrhocorax) populations Erratum to: Conserv Genet (2012) 13:1213–1230 DOI 10.1007/s10592-012-0366-6 In the original publication, Tables 3 and 6 were published with incorrect estimates of population heterozygosities. All other diversity statistics were correct as originally presented. Updated versions of Tables 3 and 6 with corrected heterozygosity estimates confirmed using Arlequin 3.5 (Excoffier and Lischer 2010) as in Dávila et al. (2014) are provided in this erratum. Discrepancies were minor for populations on the British Isles. The correct estimates for Spain are slightly larger than those reported for La Palma by Dávila et al. (2014), but this does not necessarily affect their interpretation that choughs on La Palma may have originated from multiple migration events. The original conclusion that chough populations on the British Isles have low genetic diversity compared to continental European populations remains and is now, in fact, strengthened.Peer reviewedPostprin

Icosahedral (A5) Family Symmetry and the Golden Ratio Prediction for Solar Neutrino Mixing

We investigate the possibility of using icosahedral symmetry as a family symmetry group in the lepton sector. The rotational icosahedral group, which is isomorphic to A5, the alternating group of five elements, provides a natural context in which to explore (among other possibilities) the intriguing hypothesis that the solar neutrino mixing angle is governed by the golden ratio. We present a basic toolbox for model-building using icosahedral symmetry, including explicit representation matrices and tensor product rules. As a simple application, we construct a minimal model at tree level in which the solar angle is related to the golden ratio, the atmospheric angle is maximal, and the reactor angle vanishes to leading order. The approach provides a rich setting in which to investigate the flavor puzzle of the Standard Model.Comment: 22 pages, version to be published in Phys. Rev.

A Mouse Amidase Specific for N-terminal Asparagine: the gene, the enzyme, and their function in the N-end rule pathway

The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. In both fungi and mammals, the tertiary destabilizing N-terminal residues asparagine and glutamine function through their conversion, by enzymatic deamidation, into the secondary destabilizing residues aspartate and glutamate, whose destabilizing activity requires their enzymatic conjugation to arginine, one of the primary destabilizing residues. We report the isolation and analysis of a mouse cDNA and the corresponding gene (termed Ntan1) that encode a 310-residue amidohydrolase (termed NtN-amidase) specific for N-terminal asparagine. The ~17-kilobase pair Ntan1 gene is located in the proximal region of mouse chromosome 16 and contains 10 exons ranging from 54 to 177 base pairs in length. The ~1.4-kilobase pair Ntan1 mRNA is expressed in all of the tested mouse tissues and cell lines and is down-regulated upon the conversion of myoblasts into myotubes. The Ntan1 promoter is located ~500 base pairs upstream of the Ntan1 start codon. The deduced amino acid sequence of mouse NtN-amidase is 88% identical to the sequence of its porcine counterpart, but bears no significant similarity to the sequence of the NTA1-encoded N-terminal amidohydrolase of the yeast Saccharomyces cerevisiae, which can deamidate either N-terminal asparagine or glutamine. The expression of mouse NtN-amidase in S. cerevisiae nta1Delta was used to verify that NtN-amidase retains its asparagine selectivity in vivo and can implement the asparagine-specific subset of the N-end rule. Further dissection of mouse Ntan1, including its null phenotype analysis, should illuminate the functions of the N-end rule, most of which are still unknown