10 research outputs found
The disruption of proteostasis in neurodegenerative diseases
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- Mayer MP
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- Zolkiewski M
- Zou J Guo Y, Guettouche T, et al.
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2015
- Field of study
Cells count on surveillance systems to monitor and protect the cellular proteome which, besides being highly heterogeneous, is constantly being challenged by intrinsic and environmental factors. In this context, the proteostasis network (PN) is essential to achieve a stable and functional proteome. Disruption of the PN is associated with aging and can lead to and/or potentiate the occurrence of many neurodegenerative diseases (ND). This not only emphasizes the importance of the PN in health span and aging but also how its modulation can be a potential target for intervention and treatment of human diseases.info:eu-repo/semantics/publishedVersio
Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain
- Author
- A Johnson
- AJ McCoy
- Aneel K. Aggarwal
- Angeliki Buku
- AS Konagurthu
- C Kandoth
- C Palles
- DT Nair
- DT Nair
- DT Nair
- E Johansson
- G Zheng
- GJ Kleywegt
- JM Fortune
- Kanagalaghatta R. Rajashankar
- LJ Reha-Krantz
- Louise Prakash
- LS Beese
- M Hogg
- M Hogg
- MC Franklin
- MK Swan
- P Emsley
- PD Adams
- PJ Rothwell
- PS Freemont
- PV Shcherbakova
- R Jain
- Rinku Jain
- RL Perera
- Robert E. Johnson
- S Briggs
- S Doublie
- S Lone
- SA Stocki
- Satya Prakash
- Shuang-yong Xu
- VB Chen
- W Yang
- Y Li
- Y Shamoo
- Z Otwinowski
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Hsp90 blockade modulates bullous pemphigoid IgG-induced IL-8 production by keratinocytes
- Author
- A Ambade
- A Salminen
- AL Petersen
- B Henderson
- C Dello Russo
- CB Collins
- CS Mitsiades
- Denise GrĂĽner
- Detlef Zillikens
- E Hoffmann
- E Schmidt
- E Schmidt
- E Schmidt
- E Schmidt
- F Bergh Van den
- H Teruya
- HM GĂĽrcan
- I Sigala
- JM Han
- JM Kim
- JW Rice
- KC Nelson
- KN Messingham
- M Inaoki
- M Kasperkiewicz
- M Kasperkiewicz
- M Taipale
- M Yeo
- Michael Kasperkiewicz
- MR Defee
- N Dakappagari
- N Sato
- P Stocki
- PR Jong de
- R Chen
- S Tukaj
- S Wax
- SA Lang
- SK Shimp 3rd
- SK Shimp 3rd
- Stefan Tukaj
- TB Feyerabend
- TJ Yun
- Y Kobayashi
- Z Liu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Structural basis for processive DNA synthesis by yeast DNA polymerase É›
- Author
- A Aksenova
- A Elisabeth Sauer-Eriksson
- A Morrison
- AA Larrea
- AJ McCoy
- C Kandoth
- C Palles
- C Savino
- DN Church
- E Johansson
- Else-Britt Lundström
- Erik Johansson
- FJ Asturias
- GN Murshudov
- Göran O Bylund
- H Araki
- H Araki
- H Ling
- I Isoz
- I Miyabe
- JD Pata
- JM Fortune
- KF Hartlepp
- L Holm
- L Potterton
- LN Williams
- M Garcia-Diaz
- M Garcia-Diaz
- M Hogg
- M Hogg
- M Wang
- Matthew Hogg
- MC Franklin
- MK Swan
- N Sabouri
- O Chilkova
- O Chilkova
- P Emsley
- P Emsley
- PD Adams
- Pia Osterman
- PM Burgers
- PV Shcherbakova
- R Núñez-RamĂrez
- Rais A Ganai
- RK Hamatake
- RL Perera
- S Doublié
- S Liu
- S Xia
- SA Nick McElhinny
- SA Stocki
- T Nakamura
- T Nuutinen
- T Ohya
- T Terwilliger
- T Tsubota
- W Kabsch
- W Yang
- ZF Pursell
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein
- Author
- Barik S
- Barnes AM
- Benjamin S. Glick
- Borchelt DR
- Brandner S
- Bueler H
- Butler DA
- Caughey B
- Charles E. Mays
- Chesebro B
- Cheung KL
- Clarke MC
- Daniel C. Chapman
- David B. Williams
- David Westaway
- Drisaldi B
- Flanagan WM
- Fons RD
- Goold R
- Hartmann E
- High S
- Ishikawa Y
- Jones B
- Kang SW
- Karapetyan YE
- Knowles TP
- Liang J
- Lietman CD
- Lilley BN
- Liu J
- Mallucci G
- Masel J
- Maxime Sawicki
- Mays CE
- Mays CE
- Miao M
- Mukherjee A
- Nakagaki T
- Ong DS
- Orsi A
- Pawel Stocki
- Priola SA
- Prusiner SB
- Prusiner SB
- Rane NS
- Seo Jung Hong
- Sun S
- Trevitt CR
- Voigt S
- White MD
- Xiao J
- Ye Y
- Ziegler A
- Publication venue
- 'American Society for Cell Biology (ASCB)'
- Publication date
- Field of study
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ
- Author
- A Bebenek
- A Bochkarev
- A Boulet
- A Jacewicz
- A Johnson
- Aneel K Aggarwal
- CM Joyce
- DT Nair
- E de La Fortelle
- G Yang
- G Yang
- G Yang
- G Yang
- GG Privé
- J Saturno
- JM Fortune
- JP Abrahams
- KC Sitney
- LH Hartwell
- LJ Reha-Krantz
- LJ Reha-Krantz
- Louise Prakash
- LT da Costa
- M Hogg
- M Hogg
- M Simon
- MA Blasco
- MC Franklin
- MD Winn
- Michael K Swan
- MJ Donlin
- MK Reddy
- NB Leontis
- O Kennard
- O Popanda
- P Emsley
- P Garg
- P Wu
- PJ Rothwell
- PM Burgers
- RE Goldsby
- RE Goldsby
- RE Johnson
- RJ Evans
- RN Venkatesan
- RN Venkatesan
- Robert E Johnson
- RT Pomerantz
- S Doublié
- S Liu
- S Prakash
- SA Nick McElhinny
- SA Stocki
- Satya Prakash
- SD McCulloch
- SJ Johnson
- T Flohr
- TC Lin
- TL Capson
- WC Copeland
- WN Hunter
- WN Hunter
- Y Li
- Y Shamoo
- ZF Pursell
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Identifying the key biophysical drivers, connectivity outcomes, and metapopulation consequences of larval dispersal in the sea
- Author
- A Hastings
- A Hastings
- A Moilanen
- A Saltelli
- AL Shanks
- BP Kinlan
- CB Paris
- D Bonte
- DE Bowler
- DJ Marshall
- EA Treml
- EA Treml
- EA Treml
- ED Crandall
- ED Houde
- FP Andutta
- G De’ath
- G Gerlach
- GJ Edgar
- GP Jenkins
- GP Jenkins
- GP Jenkins
- GP Jones
- GP Jones
- HR Pulliam
- HS Carson
- I Hanski
- I Hanski
- J Clobert
- J Figueiredo
- JA Pechenik
- JL Largier
- JMJ Travis
- JMJ Travis
- JS Shima
- JT Kool
- K Black
- K Weersing
- KP Black
- LA Levin
- LR Gerber
- M Beger
- M Buoro
- MI O’Connor
- NF Putman
- O Ronce
- P Saenz-Agudelo
- PJ Doherty
- PL Munday
- R Nathan
- R Nathan
- R Scott
- R Stocki
- RA Magris
- RK Cowen
- RK Cowen
- RK Cowen
- RK Cowen
- RK Cowen
- RS Lee
- S Blake
- S Coutts
- S Fossette
- S Gandon
- S Saenz-Agudelo
- S Sponaugle
- SA Levin
- SC Burgess
- SD Gaines
- SE Swearer
- SF Thrush
- SR Connolly
- T Opsahl
- TH Ricketts
- V Makler-Pick
- VM Stevens
- WF Figueira
- WH Lowe
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
An improved suppression subtractive hybridization technique to develop species-specific repetitive sequences from Erianthus arundinaceus (Saccharum complex)
- Author
- A D’Hont
- A D’Hont
- A D’Hont
- A Kato
- A Selvi
- AJ Waclawovsky
- C Harms
- C Lengauer
- CG Sagerstrom
- CN Stewart Jr
- CO Grassl
- D Straus
- DJ Heinz
- DSMC Paz
- DV Rebrikov
- E Benavente
- E Lam
- EA Galbraith
- EE Lamar
- F Lao
- Fan Yu
- FC Humann
- FM Girio
- G Piperidis
- GM Cordeiro
- GM Souza
- H Zhang
- HH Yan
- J Wu
- J-Y Ge
- JF O’Rourke
- Jiayun Wu
- JR Wu
- JW Chen
- K Wang
- K Wang
- KE Calia
- KM Devos
- L Diatchenko
- L Grivet
- L Jiang
- L Zhang
- LE Orgel
- Ling Luo
- M Camassola
- Muqing Zhang
- N Lisitsyn
- N Piperidis
- N Sarkar
- NG Gurskaya
- NS Akopyants
- NV Nair
- O Raskina
- P Rott
- PG Agron
- Q Cai
- Q Cai
- R Harakava
- RK Singh
- RL Howard
- Rukai Chen
- S Paesold
- S Sharma
- S Svitashev
- S Yang
- SA Luk’ianov
- SC Rabelo
- SL Stocki
- TX Li
- V Agrawal
- VA Amalraj
- W Zhang
- WJ Hsieh
- X Liu
- XL Liu
- XU Jing sheng
- Xueting Li
- Y Huang
- Y Umehara
- YB Pan
- Yongji Huang
- Zuhu Deng
- ZY Dai
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Systems analysis identifies miR-29b regulation of invasiveness in melanoma
- Author
- A Behren
- A Grimson
- A Jayachandran
- A Kozomara
- A Kozomara
- A Sanchez-Mejias
- A Yates
- AA Dar
- AM Poenitzsch Strong
- Andreas Behren
- B Wang
- BP Lewis
- BS Haflidadottir
- C Gene Ontology
- C Guzman
- C Levy
- C Levy
- C Sun
- CH Chou
- CL Plaisier
- CM Johannessen
- CP Bracken
- CP Bracken
- CP Bracken
- D Baek
- D Philippidou
- Daniel G. Hurley
- DG Hurley
- DG Hurley
- DJ Konieczkowski
- DM Budden
- DM Jukic
- DN Reshef
- DS Widmer
- DW Mueller
- E Obermayr
- E Penna
- E Tili
- Edmund J. Crampin
- F Felicetti
- F Felicetti
- GM Wulf
- H Guo
- H Kanemaru
- I Elson-Schwab
- J Caramel
- J Chou
- J Cursons
- J Gong
- J Jin
- J Lee
- J Schultz
- JD Hunter
- JN Weinstein
- Jonathan S. Cebon
- Joseph Cursons
- JX Zhang
- K Basso
- KL Couts
- KL Streicher
- KS Hoek
- KS Hoek
- KS Smalley
- L Hao
- M Ashburner
- M Hackenberg
- M Kappelmann
- M Reczko
- M Selbach
- M Shen
- M Wozniak
- Matthew Anaka
- MC Zipser
- MD Paraskevopoulou
- Miles C. Andrews
- MJ Schmitt
- MR Kim
- N Cloonan
- N Yamamoto
- O Shakhova
- P Khanal
- P Ru
- P Stocki
- PA Gregory
- PF Cheng
- R Denzler
- R Flavin
- R Nishikawa
- R Ramsdale
- RC Friedman
- RE Bell
- S Carreira
- S Goswami
- S Griffiths-Jones
- S Griffiths-Jones
- S Griffiths-Jones
- S Griffiths-Jones
- S Jonas
- S Memczak
- S Obchoei
- S Pinner
- S Walt Van Der
- SA Melo
- SJ Conn
- SR Alonso
- SW Eichhorn
- T Kanekura
- T Nguyen
- TD Fufa
- V Olive
- VF Bonazzi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Antimutator variants of DNA polymerases
- Author
- Alan J. Herr
- Albertson TM
- Albertson TM
- Aravind L
- Bailey S
- Barry ER
- Beard WA
- Bebenek K
- Bebenek K
- Beckman J
- Beese LS
- Bielas JH
- Boeke JD
- Bradley D. Preston
- Camps M
- Cavanaugh NA
- Chabes A
- Chao L
- Chen SH
- Chiaramonte M
- Connolly BA
- Daee DL
- Datta A
- de Visser JA
- de Wind N
- Delarue M
- Denamur E
- Doublié S
- Drake JW
- Drake JW
- Drake JW
- Drake JW
- Echols H
- Elena SF
- Eom SH
- Fijalkowska IJ
- Fijalkowska IJ
- Fijalkowska IJ
- Fijalkowska IJ
- Firbank SJ
- Fishel R
- Fogg MJ
- Fortune JM
- Franklin MC
- Friedel AM
- Gauss P
- Gibbs JS
- Gill S
- Gillin FD
- Gillin FD
- Giraud A
- Giraud A
- Goldsby RE
- Goldsby RE
- Goodman MF
- Greagg MA
- Hadjimarcou MI
- Hall JD
- Hanahan D
- Henneke G
- Herr AJ
- Hogg M
- Hopfner KP
- Huang H
- Huang M
- Hwang YT
- Iyer RR
- Jin YH
- Johnson A
- Johnson KA
- Johnson SJ
- Johnson SJ
- Joyce CM
- Kadyrov FA
- Kadyrov FA
- Kiefer JR
- Killelea T
- Kincaid K
- Kool ET
- Kumar D
- Kunkel TA
- Kunkel TA
- Kunkel TA
- Leconte AM
- Lee HR
- Lee YD
- Li L
- Li V
- Li Y
- Lindsey N. Williams
- Ling H
- Loeb LA
- Loeb LA
- Loh E
- Mao EF
- Marsischky GT
- Maruyama M
- Mathews CK
- Matsuda S
- McCulloch SD
- Mildvan AS
- Minnick DT
- Mo JY
- Morales JC
- Morales JC
- Moran S
- Morrison A
- Morrison A
- Muzyczka N
- Nilsson AI
- Northam MR
- Parsons R
- Patel PH
- Pavlov YI
- Pavlov YI
- Pavlov YI
- Perrino FW
- Petruska J
- Potapova O
- Preston BD
- Prolla TA
- Quah SK
- Reha-Krantz LJ
- Reha-Krantz LJ
- Reha-Krantz LJ
- Reha-Krantz LJ
- Reha-Krantz LJ
- Reha-Krantz LJ
- Reha-Krantz LJ
- Reha-Krantz LJ
- Reichard P
- Reitmair AH
- Reitmair AH
- Ripley LS
- Roche H
- Rothwell PJ
- Sarafianos SG
- Sawaya MR
- Schaaper RM
- Schaaper RM
- Schaaper RM
- Schaaper RM
- Schaaper RM
- Schaaper RM
- Scheuermann R
- Schmitt MW
- Shinkai A
- Shinkai A
- Shuttleworth G
- Simon M
- Sniegowski PD
- Sniegowski PD
- Sokolsky T
- Stano NM
- Steitz TA
- Stocki SA
- Sturtevant AH
- Suzuki M
- Swan MK
- Sweasy JB
- Tian W
- Tran HT
- Tran HT
- Tran HT
- Trostler M
- Trzemecka A
- Tröbner W
- Tsai YC
- Wang TS
- Wardle J
- Watson JD
- Watson JD
- Winzeler EA
- Witkin EM
- Wu X
- Xia S
- Yu L
- Zhao X
- Zhou Z
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study