7 research outputs found
Resource Management in Computer Clusters: Algorithm Design and Performance Analysis
ccomte/phd-thesis: Version 1.
Dominant motif structures
Given a motif, this MatLab code finds the dominant degrees of its vertices in hidden-variable models with degree exponent tau. Results produced by this code are presented in the paper 'Variational principle for scale-free network motifs'
Simulated data set
The simulated dataset used in the paper: Zhuozhao Zhan, Vasan S. Ramachandran, Edwin van den Heuvel, Joint modeling with time-dependent treatment and heteroskedasticity: Bayesian analysis with application to the Framingham Heart Stud
Supporting dataset for the bachelor thesis: Simulating the Spread of COVID-19 in the Netherlands
These files are videos generated by a stochastic simulation that was created by Nikki Steenbakkers under the supervision of Marko Boon and Bert Zwart (all affiliated with Eindhoven University of Technology) for her bachelor final project "Simulating the Spread of COVID-19 in the Netherlands". The report can be found in the TU/e repository of bachelor project reports: https://research.tue.nl/en/studentTheses/simulating-the-spread-of-covid-19-in-the-netherlands The report contains more information about the project and the simulation. It explicitly refers to these files
A preference-based item response theory model to measure health: concept and mathematics of the multi-attribute preference response model
Abstract Background A new patient-reported health measurement model has been developed to quantify descriptions of health states. Known as the multi-attribute preference response (MAPR) model, it is based on item response theory. The response task in the MAPR is for a patient to judge whether hypothetical health-state descriptions are better or worse than his/her own health status. Methods In its most simple form MAPR is a Rasch model where for each respondent on the same unidimensional health scale values are estimated of their own health status and values of the hypothetical comparator health states. These values reflect the quality or severity of the health states. Alternatively, the respondents are offered health-state descriptions that are based on a classification system (e.g., multi-attribute) with a fixed number of health attributes, each with a limited number of levels. In the latter variant, the weights of the levels of the attributes in the descriptive system, which represents the range of the health states, are estimated. The results of a small empirical study are presented to illustrate the procedures of the MAPR model and possible extensions of the model are discussed. Results The small study that we conducted to illustrate the procedure and results of our proposed method to measure the quality of health states and patientsâ own health status showed confirming results. Conclusions This paper introduces the typical MAPR model and shows how it extends the basic Rasch model with a regression function for the attributes of the health-state classification system
Supplementary material from "Trade-offs between mobility restrictions and transmission of SARS-CoV-2"
In their response to the COVID-19 outbreak, governments face the dilemma to balance public health and economy. Mobility plays a central role in this dilemma because the movement of people enables both economic activity and virus spread. We use mobility data in the form of counts of travellers between regions, to extend the often-used SEIR models to include mobility between regions. We quantify the trade-off between mobility and infection spread in terms of a single parameter, to be chosen by policy makers, and propose strategies for restricting mobility so that the restrictions are minimal while the infection spread is effectively limited. We consider restrictions where the country is divided into regions, and study scenarios where mobility is allowed within these regions, and disallowed between them. We propose heuristic methods to approximate optimal choices for these regions. We evaluate the obtained restrictions based on our trade-off. The results show that our methods are especially effective when the infections are highly concentrated, e.g., around a few municipalities, as resulting from superspreading events that play an important role in the spread of COVID-19. We demonstrate our method in the example of the Netherlands. The results apply more broadly when mobility data is available
Intrauterine resuscitation during the second stage of term labour by maternal hyperoxygenation versus conventional care: study protocol for a randomised controlled trial (INTEREST O2)
Abstract Background Perinatal asphyxia is, even in developed countries, one the major causes of neonatal morbidity and mortality. Therefore, if foetal distress during labour is suspected, one should try to restore foetal oxygen levels or aim for immediate delivery. However, studies on the effect of intrauterine resuscitation during labour are scarce. We designed a randomised controlled trial to investigate the effect of maternal hyperoxygenation on the foetal condition. In this study, maternal hyperoxygenation is induced for the treatment of foetal distress during the second stage of term labour. Methods/design This study is a single-centre randomised controlled trial being performed in a tertiary hospital in The Netherlands. From among cases of a suboptimal or abnormal foetal heart rate pattern during the second stage of term labour, a total of 116 patients will be randomised to the control group, where normal care is provided, or to the intervention group, where before normal care 100% oxygen is supplied to the mother by a non-rebreathing mask until delivery. The primary outcome is change in foetal heart rate pattern. Secondary outcomes are Apgar score, mode of delivery, admission to the neonatal intensive care unit and maternal side effects. In addition, blood gas values and malondialdehyde are determined in umbilical cord blood. Discussion This study will be the first randomised controlled trial to investigate the effect of maternal hyperoxygenation for foetal distress during labour. This intervention should be recommended only as a treatment for intrapartum foetal distress, when improvement of the foetal condition is likely and outweighs maternal and neonatal side effects. Trial registration EudraCT, 2015-001654-15; registered on 3 April 2015. Dutch Trial Register, NTR5461; registered on 20 October 2015
