3 research outputs found
Longâterm followâup of stereotactic radiosurgery for head and neck malignancies
BackgroundStereotactic radiosurgery is widely applied to deliver additional dose to head and neck tumors. However, its safety and efficacy remains equivocal.MethodsOne hundred eightyâfour patients with primary head and neck cancers treated between January 1990 and August 2012 with Gamma Knife stereotactic radiosurgery were retrospectively reviewed.ResultsTwo hundred fifteen sites were treated with Gamma Knife stereotactic radiosurgery among 184 patients. Fiftyâone percent of patients received concurrent external beam radiotherapy (EBRT), 72% had prior surgery, and 46% received chemotherapy. Most (44%) had squamous cell carcinoma and most patients (65%) were treated for recurrent disease. With a median followâup of 17.3 months, 12âmonth local control was 82%. Late effects occurred in 59 patients with the most common being temporal lobe necrosis (15 patients).ConclusionRadiosurgery can provide tumor control for patients with head and neck cancers involving the skull base. Longâterm followâup is important in survivors to identify late effects. © 2014 Wiley Periodicals, Inc. Head Neck 37: 1557â1562, 2015Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/115998/1/hed23798.pd