16,660 research outputs found
Development of sprayed ceramic seal systems for turbine gas path sealing
A ceramic seal system is reported that employs plasma-sprayed graded metal/ceramic yttria stabilized zirconium oxide (YSZ). The performance characteristics of several YSZ configurations were determined through rig testing for thermal shock resistance, abradability, and erosion resistance. Results indicate that this type of sealing system offers the potential to meet operating requirements of future gas turbine engines
Problems which are well-posed in a generalized sense with applications to the Einstein equations
In the harmonic description of general relativity, the principle part of
Einstein equations reduces to a constrained system of 10 curved space wave
equations for the components of the space-time metric. We use the
pseudo-differential theory of systems which are well-posed in the generalized
sense to establish the well-posedness of constraint preserving boundary
conditions for this system when treated in second order differential form. The
boundary conditions are of a generalized Sommerfeld type that is benevolent for
numerical calculation.Comment: Final version to appear in Classical and Qunatum Gravit
Adaptive grid methods for Q-tensor theory of liquid crystals : a one-dimensional feasibility study
This paper illustrates the use of moving mesh methods for solving partial differential equation (PDE) problems in Q-tensor theory of liquid crystals. We present the results of an initial study using a simple one-dimensional test problem which illustrates the feasibility of applying adaptive grid techniques in such situations. We describe how the grids are computed using an equidistribution principle, and investigate the comparative accuracy of adaptive and uniform grid strategies, both theoretically and via numerical examples
Probing Pair-Correlated Fermionic Atoms through Correlations in Atom Shot Noise
Pair-correlated fermionic atoms are created through dissociation of weakly
bound molecules near a magnetic-field Feshbach resonance. We show that
correlations between atoms in different spin states can be detected using the
atom shot noise in absorption images. Furthermore, using time-of-Flight imaging
we have observed atom pair correlations in momentum space
Gowdy waves as a test-bed for constraint-preserving boundary conditions
Gowdy waves, one of the standard 'apples with apples' tests, is proposed as a
test-bed for constraint-preserving boundary conditions in the non-linear
regime. As an illustration, energy-constraint preservation is separately tested
in the Z4 framework. Both algebraic conditions, derived from energy estimates,
and derivative conditions, deduced from the constraint-propagation system, are
considered. The numerical errors at the boundary are of the same order than
those at the interior points.Comment: 5 pages, 1 figure. Contribution to the Spanish Relativity Meeting
200
Lymphatic expression of CLEVER-1 in breast cancer and its relationship with lymph node metastasis
BACKGROUND
Mechanisms regulating breast cancer lymph node metastasis are unclear. Staining of CLEVER-1 (common lymphatic endothelial and vascular endothelial receptor-1) in human breast tumors was used, along with in vitro techniques, to assess involvement in the metastatic process.
METHODS
148 sections of primary invasive breast cancers, with 10 yr follow-up, were stained with anti-CLEVER-1. Leukocyte infiltration was assessed, along with involvement of specific subpopulations by staining with CD83 (mature dendritic cells, mDC), CD209 (immature DC, iDC) and CD68 (macrophage, MĎ). In vitro expression of CLEVER-1 on lymphatic (LEC) and blood endothelial cells (BEC) was examined by flow cytometry.
RESULTS
In vitro results showed that although both endothelial cell types express CLEVER-1, surface expression was only evident on LEC. In tumour sections CLEVER-1 was expressed in blood vessels (BV, 61.4% of samples), lymphatic vessels (LV, 18.2% of samples) and in MĎ/DCs (82.4% of samples). However, only CLEVER-1 expression in LV was associated with LN metastasis (p = 0.027) and with MĎ indices (p = 0.021). Although LV CLEVER-1 was associated with LN positivity there was no significant correlation with recurrence or overall survival, BV CLEVER-1 expression was, however, associated with increased risk of recurrence (p = 0.049). The density of inflammatory infiltrate correlated with CLEVER-1 expression in BV (p < 0.001) and LV (p = 0.004).
CONCLUSIONS
The associations between CLEVER-1 expression on endothelial vessels and macrophage/leukocyte infiltration is suggestive of its regulation by inflammatory conditions in breast cancer, most likely by macrophage-associated cytokines. Its upregulation on LV, related surface expression, and association with LN metastasis suggest that it may be an important mediator of tumor cell metastasis to LN
On asymptotically flat solutions of Einstein's equations periodic in time II. Spacetimes with scalar-field sources
We extend the work in our earlier article [4] to show that time-periodic,
asymptotically-flat solutions of the Einstein equations analytic at scri, whose
source is one of a range of scalar-field models, are necessarily stationary. We
also show that, for some of these scalar-field sources, in stationary,
asymptotically-flat solutions analytic at scri, the scalar field necessarily
inherits the symmetry. To prove these results we investigate miscellaneous
properties of massless and conformal scalar fields coupled to gravity, in
particular Bondi mass and its loss.Comment: 29 pages, published in Class. Quant. Grav. Replaced. Typos corrected,
version which appeared in Class. Quant.Gra
Stable radiation-controlling boundary conditions for the generalized harmonic Einstein equations
This paper is concerned with the initial-boundary value problem for the
Einstein equations in a first-order generalized harmonic formulation. We impose
boundary conditions that preserve the constraints and control the incoming
gravitational radiation by prescribing data for the incoming fields of the Weyl
tensor. High-frequency perturbations about any given spacetime (including a
shift vector with subluminal normal component) are analyzed using the
Fourier-Laplace technique. We show that the system is boundary-stable. In
addition, we develop a criterion that can be used to detect weak instabilities
with polynomial time dependence, and we show that our system does not suffer
from such instabilities. A numerical robust stability test supports our claim
that the initial-boundary value problem is most likely to be well-posed even if
nonzero initial and source data are included.Comment: 27 pages, 4 figures; more numerical results and references added,
several minor amendments; version accepted for publication in Class. Quantum
Gra
Perspective on gravitational self-force analyses
A point particle of mass moving on a geodesic creates a perturbation
, of the spacetime metric , that diverges at the particle.
Simple expressions are given for the singular part of and its
distortion caused by the spacetime. This singular part h^\SS_{ab} is
described in different coordinate systems and in different gauges. Subtracting
h^\SS_{ab} from leaves a regular remainder . The
self-force on the particle from its own gravitational field adjusts the world
line at \Or(\mu) to be a geodesic of ; this adjustment
includes all of the effects of radiation reaction. For the case that the
particle is a small non-rotating black hole, we give a uniformly valid
approximation to a solution of the Einstein equations, with a remainder of
\Or(\mu^2) as .
An example presents the actual steps involved in a self-force calculation.
Gauge freedom introduces ambiguity in perturbation analysis. However,
physically interesting problems avoid this ambiguity.Comment: 40 pages, to appear in a special issue of CQG on radiation reaction,
contains additional references, improved notation for tensor harmonic
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