3,812 research outputs found

    Yo no fumo

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    Victoria Rodrigo, PhD- Serie Leamos’ EditorProfessor of Spanish World Languages and Cultures DepartmentGeorgia State Universityhttps://scholarworks.gsu.edu/wcl_leamos/1035/thumbnail.jp

    The Shallow Geological Model: mapping and monitoring the marine landscape

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    Managing our seas without a sound knowledge of the sea-bed environment and the processes that shape the sea-bed characteristics makes it difficult to conserve key areas, maintain biodiversity and economically develop our marine resources in an efficient and sustainable way. Recent developments in marine landscape mapping, visualisation techniques and instant data access provide timely, proven technologies that are now in widespread use

    Are infestations of Cymomelanodactylus killing Acropora cytherea in the Chagos archipelago?

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    Associations between branching corals and infaunal crabs are well known, mostly due to the beneficial effects of Trapezia and Tetralia crabs in protecting host corals from crown-of-thorns starfish (e.g., Pratchett et al. 2000) and/or sedimentation (Stewart et al. 2006). These crabs are obligate associates of live corals and highly prevalent across suitable coral hosts, with 1–2 individuals per colony (Patton 1994). Cymo melanodactylus (Fig. 1) are also prevalent in branching corals, mostly Acropora, and are known to feed on live coral tissue, but are generally found in low abundance (<3 per colony) and do not significantly affect their host corals (e.g., Patton 1994). In the Chagos archipelago, however, infestations of Cymo melanodactylus were found on recently dead and dying colonies of Acropora cytherea

    An early giant planet instability recorded in asteroidal meteorites

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    Giant planet migration appears widespread among planetary systems in our Galaxy. However, the timescales of this process, which reflect the underlying dynamical mechanisms, are not well constrained, even within the solar system. Since planetary migration scatters smaller bodies onto intersecting orbits, it would have resulted in an epoch of enhanced bombardment in the solar system's asteroid belt. To accurately and precisely quantify the timescales of migration, we interrogate thermochronologic data from asteroidal meteorites, which record the thermal imprint of energetic collisions. We present a database of 40K-40Ar system ages from chondrite meteorites and evaluate it with an asteroid-scale thermal code coupled to a Markov chain Monte Carlo inversion. Simulations require bombardment in order to reproduce the observed age distribution and identify a bombardment event beginning ~11 million years after the Sun formed. Our results associate a giant planet instability in our solar system with the dissipation of the gaseous protoplanetary disk.Comment: 24 pages, 4 figures, 2 tables, 10 extended data items (8 figures, 2 tables). Under review at Nature Astronom

    Revision of the \u3cem\u3eMesobuthus caucasicus\u3c/em\u3e complex from Central Asia, with descriptions of six new species (Scorpiones: Buthidae)

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    A widespread Mesobuthus caucasicus complex, which includes some of the most common scorpions found from the Caucasus to China, is revised for the first time based on new extensive collections from Central Asia, using both morphological and DNA marker data. Mesobuthus caucasicus (Nordmann, 1840), s.str. is restricted to the Caucasus Mts. Four taxa are elevated to species rank: M. fuscus (Birula, 1897) (Tajikistan), M. intermedius (Birula, 1897) (Tajikistan), M. kaznakovi (Birula, 1904) (Tajikistan, Uzbekistan), and M. parthorum (Pocock, 1889) (Afghanistan, Iran, Turkmenistan). Six new species are described: M. brutus sp. n. (Iran), M. elenae sp. n. (Tajikistan, Uzbekistan), M. gorelovi sp. n. (Kazakhstan, Turkmenistan, Uzbekistan), M. kreuzbergi sp. n. (Tajikistan, Uzbekistan), M. mischi sp. n. (Afghanistan), and M. nenilini sp. n. (Uzbekistan). The most common species in Central Asia is a psammophilic Mesobuthus gorelovi sp. n., widespread through lowland sand deserts across Turkmenistan (Karakum), Uzbekistan (Kizylkum), and Kazakhstan (north to Baigakum and Moyinkum). A key to all studied species is provided. A DNA phylogeny based on COI and 16S rRNA markers is presented including nine Central Asian species (M. elenae sp. n., M. fuscus, M. gorelovi sp. n., M. intermedius, M. kaznakovi, M. kreuzbergi sp. n., M. mischi sp. n., M. nenilini sp. n., and M. parthorum) and M. caucasicus from Turkey. A deep phylogenetic diversity across Central Asia is revealed. Historical biogeographic scenarios for this scorpion group are discussed, including fragmentation in mountain valleys and expansion across sand deserts in Central Asia. The monotypic scorpion genus Afghanobuthus Lourenço, 2005 and its single species A. naumanni Lourenço, 2005, from Afghanistan, are demonstrated to be junior synonyms, respectively, of Mesobuthus Vachon, 1950, and M. parthorum (Pocock, 1889) from the same area

    The Genetic Requirements for Fast and Slow Growth in Mycobacteria

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    Mycobacterium tuberculosis infects a third of the world's population. Primary tuberculosis involving active fast bacterial replication is often followed by asymptomatic latent tuberculosis, which is characterised by slow or non-replicating bacteria. Reactivation of the latent infection involving a switch back to active bacterial replication can lead to post-primary transmissible tuberculosis. Mycobacterial mechanisms involved in slow growth or switching growth rate provide rational targets for the development of new drugs against persistent mycobacterial infection. Using chemostat culture to control growth rate, we screened a transposon mutant library by Transposon site hybridization (TraSH) selection to define the genetic requirements for slow and fast growth of Mycobacterium bovis (BCG) and for the requirements of switching growth rate. We identified 84 genes that are exclusively required for slow growth (69 hours doubling time) and 256 genes required for switching from slow to fast growth. To validate these findings we performed experiments using individual M. tuberculosis and M. bovis BCG knock out mutants. We have demonstrated that growth rate control is a carefully orchestrated process which requires a distinct set of genes encoding several virulence determinants, gene regulators, and metabolic enzymes. The mce1 locus appears to be a component of the switch to slow growth rate, which is consistent with the proposed role in virulence of M. tuberculosis. These results suggest novel perspectives for unravelling the mechanisms involved in the switch between acute and persistent TB infections and provide a means to study aspects of this important phenomenon in vitro

    Foot health education for people with rheumatoid arthritis : the practitioner's perspective

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    Background: Patient education is considered to be a key role for podiatrists in the management of patients with rheumatoid arthritis (RA). Patient education has undoubtedly led to improved clinical outcomes, however no attempts have been made to optimise its content or delivery to maximise benefits within the context of the foot affected by rheumatoid arthritis. The aim of this study was to identify the nature and content of podiatrists' foot health education for people with RA. Any potential barriers to its provision were also explored. Methods: A focus group was conducted. The audio dialogue was recorded digitally, transcribed verbatim and analysed using a structured, thematic approach. The full transcription was verified by the focus group as an accurate account of what was said. The thematic analysis framework was verified by members of the research team to ensure validity of the data. Results: Twelve members (all female) of the north west Podiatry Clinical Effectiveness Group for Rheumatology participated. Six overarching themes emerged: (i) the essence of patient education; (ii) the content; (iii) patient-centred approach to content and timing; (iv) barriers to provision; (v) the therapeutic relationship; and (vi) tools of the trade. Conclusion: The study identified aspects of patient education that this group of podiatrists consider most important in relation to its: content, timing, delivery and barriers to its provision. General disease and foot health information in relation to RA together with a potential prognosis for foot health, the role of the podiatrist in management of foot health, and appropriate self-management strategies were considered to be key aspects of content, delivered according to the needs of the individual. Barriers to foot health education provision, including financial constraints and difficulties in establishing effective therapeutic relationships, were viewed as factors that strongly influenced foot health education provision. These data will contribute to the development of a patient-centred, negotiated approach to the provision of foot health education for people with RA
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