Exploring the Program-Site Alliance: Building Partnerships Between Counseling Programs and Fieldwork Sites

Practicum and internship experiences are critical in students’ professional development in counselor education programs, and the dynamics that occur between programs and field sites can impact these experiences. A program-site alliance is a measure of how well these entities work together. Using Interpretive Phenomenological Analysis, the authors interviewed five site supervisors and found five themes (Site Supervisor Role, Communication Within the Program-Site Alliance, Independent Mutualism, Regulated Support, and Inconsistency Between Program-Site Alliance) capturing the essence of the program-site relationship. The authors explore implications for practice and future research

Bundling of actin filaments by aorta caldesmon is not related to its regulatory function

AbstractCa2+-sensitive thin filaments from vascular smooth muscle were disassembled into their constituent proteins, actin, tropomyosin and caldesmon. Caldesmon bound to both actin and to actin-tropomyosin and inhibited actin-tropomyosin activation of skeletal muscle myosin MgATPase. It also promoted the aggregation of actin or actin-tropomyosin into parallel aligned bundles. Quantitative electron microscopy measurements showed that with 1.1 μM actin-tropomyosin, 1.6 ± 0.5% (n = 3) of the filaments were in bundles. At 0.073 μM, caldesmon inhibited MgATPase activity by 50%, whereas bundling was 3.0 ± 1.3% (n = 4). At 0.37 μM caldesmon, MgATPase inhibition was 83% while 28.1 ± 6.9% (n = 4) of filaments were in bundles. Experiments at 4.4 μM in which MgATPase and bundling were measured in the same samples gave similar results. Small bundles of 2–3 filaments showed the most frequent occurrence at 1.1 μM actin. At 4.4 μM actin the most common bundle size was 3-5 filaments, with the occasional occurrence of large bundles consisting of up to 120 filaments. The incidence of bundling was the same in the presence and absence of tropomyosin. Thus caldesmon can induce the formation of actin bundles but this property bears no relationship to its inhibition of MgATPase activity

From Readiness to Action: Social Justice Training in Practicum

Social justice is an imperative within counseling and is recognized through the American Counseling Association\u27s code of ethics, nationally endorsed competencies, and the Council for Accreditation of Counseling and Related Educational Programs. The authors completed a phenomenological study exploring the experience of five master’s-level counseling students in their practicum course relative to their development of a socially just counseling approach. The authors identified themes to provide a textural-structural description of how students experienced the transition towards social action. Moving from readiness to action encompassed previous experiences, the learning community, and change agents including awareness, responsibility, motivation, and comfort. Implications for educators and supervisors of professional counselors are provided

Nitrogen-bridged, natural product-like octahydrobenzofurans and octahydroindoles: scope and mechanism of bridge-forming reductive amination via caged heteroadamantanes

The biological significance of sp3-rich synthetic scaffolds with natural product-like features yet distinct global frameworks is being increasingly recognised in medicinal chemistry and biochemistry. Taking inspiration from the vast array of bioactive, bridged alkaloids, we report the synthesis of unique, densely functionalised tricyclic scaffolds based on nitrogen-bridged, octahydrobenzofurans and octahydroindoles. These heterocycle-rich frameworks were assembled by a one-pot, two-step bridge-forming reductive amination process, which was shown to proceed via caged, heteroadamantane intermediates that thermodynamically drive an exo–endo epimerisation, enabling intramolecular azaMichael addition over the concave face of the fused bicyclic precursors. In addition to evaluating the scope of this aza bridge-forming reaction, further stereochemical complexity was introduced by subsequent diastereoselective ketone reductions and other manipulations. Finally, strategic diversity points (amino, carboxy) were decorated with common medicinal chemistry fragments, providing a set of exemplar derivatives with Lipinski compliant physicochemical properties

Altruism, Commitment, and Leadership in High School Mentors

This study investigated the effects of mentoring on selected attributes among high school mentors. Three attributes were explored: altruism, commitment to school, and student leadership. Seventy-four high school juniors and seniors participated as mentors to high school freshmen students. Mentors participated in a leadership training program prior to beginning their mentoring activities. Pre- and post-test measures of the three attributes were administered. Results showed no significant increase in altruism or commitment scores. Unexpectedly, the mentoring experience produced a significant decrease in the perception of leadership scores. Implications for implementing a mentoring program in a high school setting are discussed

Altruism, Commitment, and Leadership in High School Mentors

This study investigated the effects of mentoring on selected attributes among high school mentors. Three attributes were explored: altruism, commitment to school, and student leadership. Seventy-four high school juniors and seniors participated as mentors to high school freshmen students. Mentors participated in a leadership training program prior to beginning their mentoring activities. Pre- and post-test measures of the three attributes were administered. Results showed no significant increase in altruism or commitment scores. Unexpectedly, the mentoring experience produced a significant decrease in the perception of leadership scores. Implications for implementing a mentoring program in a high school setting are discussed

Southeastern Broiler Gaseous and Particulate Matter Emissions Monitoring

This report describes the measurement methodologies and results of gaseous and particulate matter (PM) emissions (ammonia, carbon dioxide, hydrogen sulfide, non-methane hydrocarbon or NMHC, total suspended particulate or TSP, PM10, and PM2.5) from two typical Tyson broiler production houses located on two separate farm sites in western Kentucky. Each broiler house was 43 ft x 510 ft (13 m x 155 m), with an initial, nominal placement of 25,800 (winter) to 24,400 (summer) Cobb-Cobb straight-run broilers per flock. The broilers were grown on new or built-up litter to an average age of 52 d (50 - 54 d), with flock downtime (i.e., empty house) ranging from 9 to 41 d